List of works - Aliaksandr Druz

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

scientific article (publication date: 2015)

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

scientific article

Corrigendum: Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer

scientific article published on 01 June 2017

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

scientific article published on 11 December 2019

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

scientific article

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

scientific article

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

scientific article

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

scientific article

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

scientific article published on 04 June 2018

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

scientific article

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

scientific article published on November 2016

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

scientific article published on 30 December 2015

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

scientific article published in Nature Communications

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

scientific article published on 12 March 2019

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

scientific article

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

scientific article published on March 2017

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

scientific article

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

scientific article

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

scientific article

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

scientific article published on 06 June 2016

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

scientific article published on 20 February 2020

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

scientific article

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

scientific article published on March 2017

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

scientific article published on April 2017

Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer

scientific article published on 20 February 2017

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

scientific article published on 4 March 2015

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

scientific article published in December 2017

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

scientific article

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

scientific article

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

scientific article

Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

scientific article published in October 2014

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

scientific article published on 01 April 2020

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

scientific article published on 31 August 2016

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

scientific article published on 8 March 2017

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

scientific article

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

scientific article

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

scientific article

Transplanting supersites of HIV-1 vulnerability

scientific article

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

scientific article

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

scientific article published on 16 February 2018

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

scientific article published in October 2014

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

scientific article

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop

scientific article published on May 2017

List of works by Aliaksandr Druz

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface

Corrigendum: Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer

Crystal Structure and Immunogenicity of the DS-Cav1-Stabilized Fusion Glycoprotein From Respiratory Syncytial Virus Subtype B

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

Crystal structures of trimeric HIV envelope with entry inhibitors BMS-378806 and BMS-626529.

Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies

Enhanced potency of a broadly neutralizing HIV-1 antibody in vitro improves protection against lentiviral infection in vivo

Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody

Identification of a CD4-Binding-Site Antibody to HIV that Evolved Near-Pan Neutralization Breadth.

Immunogenicity of a Prefusion HIV-1 Envelope Trimer in Complex with a Quaternary-Structure-Specific Antibody

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

Lattice engineering enables definition of molecular features allowing for potent small-molecule inhibition of HIV-1 entry

Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual

Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody

Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide.

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design

Platelet-derived growth factor-α receptor is the cellular receptor for human cytomegalovirus gHgLgO trimer

Preclinical Development of a Fusion Peptide Conjugate as an HIV Vaccine Immunogen

Prefusion F-specific antibodies determine the magnitude of RSV neutralizing activity in human sera

Protection of calves by a prefusion-stabilized bovine RSV F vaccine

Quantification of the Impact of the HIV-1-Glycan Shield on Antibody Elicitation

Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer

Single-Chain Soluble BG505.SOSIP gp140 Trimers as Structural and Antigenic Mimics of Mature Closed HIV-1 Env.

Soluble Prefusion Closed DS-SOSIP.664-Env Trimers of Diverse HIV-1 Strains

Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.

Structure and immune recognition of trimeric pre-fusion HIV-1 Env.

Structure of BMS-806, a Small-molecule HIV-1 Entry Inhibitor, Bound to BG505 SOSIP.664 HIV-1 Env Trimer.

Structure of Super-Potent Antibody CAP256-VRC26.25 in Complex with HIV-1 Envelope Reveals a Combined Mode of Trimer-Apex Recognition

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design

Thermoresponsive Polymer Nanoparticles Co-deliver RSV F Trimers with a TLR-7/8 Adjuvant.

Transplanting supersites of HIV-1 vulnerability

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

Uncleaved Soluble gp140 Constructs with Retained Native-like Trimer Conformation and Antigenicity.

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop