List of works - Elisa Fossale

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

scientific journal article

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

scientific article

Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative ⬇️

scientific article published on August 12, 2011

Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells

scientific article published on 01 July 2006

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy ⬇️

scientific article published on April 16, 2013

Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice

scientific article published on 10 May 2006

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

scientific article published on 22 August 2005

HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation

scientific article

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

scientific article published on 5 March 2001

Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice

scientific article published in September 2002

Inaugural Huntington Disease Clinical Research Symposium Organized by the Huntington Study Group.

scientific article published in April 2008

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

scientific article

Meclizine is neuroprotective in models of Huntington's disease ⬇️

scientific article published on October 25, 2010

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis

scientific article

Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease

scientific article

Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice

scientific article published in March 2003

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis ⬇️

scientific article published on March 29, 2011

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.

scientific article

List of works by Elisa Fossale

Autophagy is disrupted in a knock-in mouse model of juvenile neuronal ceroid lipofuscinosis

Cholesterol defect is marked across multiple rodent models of Huntington's disease and is manifest in astrocytes

Differential effects of the Huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative ⬇️

Discovery of bioactive small-molecule inhibitor of poly adp-ribose polymerase: implications for energy-deficient cells

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy ⬇️

Genetic background modifies nuclear mutant huntingtin accumulation and HD CAG repeat instability in Huntington's disease knock-in mice

HD CAG repeat implicates a dominant property of huntingtin in mitochondrial energy metabolism

HdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid Accumulation

Huntingtin's neuroprotective activity occurs via inhibition of procaspase-9 processing

Identification of a presymptomatic molecular phenotype in Hdh CAG knock-in mice

Inaugural Huntington Disease Clinical Research Symposium Organized by the Huntington Study Group.

Lack of huntingtin promotes neural stem cells differentiation into glial cells while neurons expressing huntingtin with expanded polyglutamine tracts undergo cell death

Meclizine is neuroprotective in models of Huntington's disease ⬇️

Membrane trafficking and mitochondrial abnormalities precede subunit c deposition in a cerebellar cell model of juvenile neuronal ceroid lipofuscinosis

Rrs1 is involved in endoplasmic reticulum stress response in Huntington disease

Specific progressive cAMP reduction implicates energy deficit in presymptomatic Huntington's disease knock-in mice

Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis ⬇️

Widespread disruption of repressor element-1 silencing transcription factor/neuron-restrictive silencer factor occupancy at its target genes in Huntington's disease.