List of works - Jessica R Frankum

Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

scientific article

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity

scientific article

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

scientific article

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade

scientific article published on 15 February 2018

Functional characterization of EMSY gene amplification in human cancers

scientific article published on 7 July 2011

Functional viability profiles of breast cancer

scientific article

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

scientific article published on 10 May 2018

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells

scientific article

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity

scientific article

Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers

scientific article published on 13 March 2015

Germline mutations in RAD51D confer susceptibility to ovarian cancer

scientific article (publication date: 7 August 2011)

High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

scientific article

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

scientific article published on 2 March 2016

Modeling Therapy Resistance in BRCA1/2-Mutant Cancers

scientific article published on 15 June 2017

Searching for synthetic lethality in cancer

scientific article published on 20 January 2011

Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

scientific article

Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells

scientific article

Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers

scientific article

List of works by Jessica R Frankum

Characterization of the genomic features and expressed fusion genes in micropapillary carcinomas of the breast

Complementary genetic screens identify the E3 ubiquitin ligase CBLC, as a modifier of PARP inhibitor sensitivity

Cross-platform pathway-based analysis identifies markers of response to the PARP inhibitor olaparib

DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade

Functional characterization of EMSY gene amplification in human cancers

Functional viability profiles of breast cancer

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells

Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity

Genomic Complexity Profiling Reveals That HORMAD1 Overexpression Contributes to Homologous Recombination Deficiency in Triple-Negative Breast Cancers

Germline mutations in RAD51D confer susceptibility to ovarian cancer

High-throughput RNA interference screening using pooled shRNA libraries and next generation sequencing

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

Modeling Therapy Resistance in BRCA1/2-Mutant Cancers

Searching for synthetic lethality in cancer

Selective Inhibition of SIN3 Corepressor with Avermectins as a Novel Therapeutic Strategy in Triple-Negative Breast Cancer

Synthetic lethality of PARP and NAMPT inhibition in triple-negative breast cancer cells

Targeting p90 ribosomal S6 kinase eliminates tumor-initiating cells by inactivating Y-box binding protein-1 in triple-negative breast cancers