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List of works by Shigeto Sato

14-3-3eta is a novel regulator of parkin ubiquitin ligase

scientific article

ATP13A2 deficiency induces a decrease in cathepsin D activity, fingerprint-like inclusion body formation, and selective degeneration of dopaminergic neurons

scientific journal article

Aging-related motor function and dopaminergic neuronal loss in C57BL/6 mice

scientific article published on 23 March 2020

Animal models of Parkinson's disease: similarities and differences between the disease and models

scientific article published on October 2007

Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition

scientific article

DJ-1 associates with synaptic membranes

scientific article published on 30 May 2011

Decline of striatal dopamine release in parkin-deficient mice shown by ex vivo autoradiography

scientific article published in November 2006

Detailed analysis of mitochondrial respiratory chain defects caused by loss of PINK1.

scientific article published in August 2014

Dopaminergic Neuron-Specific Autophagy-Deficient Mice

scientific article published on 01 January 2018

Evidence that phosphorylated ubiquitin signaling is involved in the etiology of Parkinson's disease.

scientific article published on 25 May 2017

Functional Neurons Generated from T Cell-Derived Induced Pluripotent Stem Cells for Neurological Disease Modeling

scientific article published on 9 February 2016

Genetic mutations and functions of PINK1.

scientific article published on 23 July 2011

Genetic mutations and mitochondrial toxins shed new light on the pathogenesis of Parkinson's disease

scientific article published on August 2011

Induction of PINK1/Parkin-Mediated Mitophagy

scientific article published on 31 March 2017

LRRK2 I2020T mutation is associated with tau pathology

scientific article published on 22 April 2012

Loss of Parkin contributes to mitochondrial turnover and dopaminergic neuronal loss in aged mice

scientific article published on 15 December 2019

Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c

scientific article

Loss of autophagy in dopaminergic neurons causes Lewy pathology and motor dysfunction in aged mice

scientific article published on 12 February 2018

Loss of nuclear REST/NRSF in aged-dopaminergic neurons in Parkinson's disease patients

scientific article published on 23 January 2019

Lysosomal Storage of Subunit c of Mitochondrial ATP Synthase in Brain-Specific Atp13a2-Deficient Mice

scientific article published on 19 October 2016

Lysosomal defects in ATP13A2 and GBA associated familial Parkinson's disease

scientific article published on 11 September 2017

Metabolomics-based identification of metabolic alterations in PARK2

scientific article published on 21 February 2019

Mitochondrial dysfunction associated with increased oxidative stress and α-synuclein accumulation in PARK2 iPSC-derived neurons and postmortem brain tissue

scientific article published on 6 October 2012

Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects

scientific article

Molecular mechanism of early-onset familial PD ⬇️

scientific article published on January 1, 2012

Molecular pathogenesis of Parkinson's disease: update

scientific article published on 03 December 2011

PARK2/Parkin-mediated mitochondrial clearance contributes to proteasome activation during slow-twitch muscle atrophy via NFE2L1 nuclear translocation

scientific article

PINK1 autophosphorylation upon membrane potential dissipation is essential for Parkin recruitment to damaged mitochondria

scientific article

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy

scientific article

PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy

scientific article (publication date: 19 April 2010)

PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy

scientific article

Parkin regulates kainate receptors by interacting with the GluK2 subunit

scientific article

Parkin stabilizes PINK1 through direct interaction

scientific article published on 7 April 2009

Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease

scientific article

Pathogenic insights to Parkin-linked model mice

scientific article published on 29 April 2020

Programmed cell death-2 isoform1 is ubiquitinated by parkin and increased in the substantia nigra of patients with autosomal recessive Parkinson's disease

scientific article

Progress in the pathogenesis and genetics of Parkinson's disease

scientific article published on June 2008

The pathomechanisms of young-onset Parkinson's disease (PD), approach to the causes of PD form the mechanisms of insulin secretion system ⬇️

scientific article published on 01 November 2011

Urinary 8-hydroxydeoxyguanosine levels as a biomarker for progression of Parkinson disease

scientific article

Variants in saposin D domain of prosaposin gene linked to Parkinson's disease

scientific article published on 23 March 2020

Zonisamide reduces cell death in SH-SY5Y cells via an anti-apoptotic effect and by upregulating MnSOD.

scientific article published on 25 June 2010

[Treatments for Parkinson's Disease -Essential Knowledge for General Physicians - Topics: II. Familial Parkinson's Disease Causative Genes Shed Light on the Molecular Pathogenesis]

scientific article published on 01 August 2015

p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria

scientific article

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