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List of works by Mª José Gómez-Lechón

A simple transcriptomic signature able to predict drug-induced hepatic steatosis.

scientific article published on 28 January 2014

Cytometric analysis for drug-induced steatosis in HepG2 cells.

scientific article

Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS.

scientific article published in December 2003

Establishment and characterization of immortal hepatocytes derived from various transgenic mouse lines.

scientific article

HepG2 cells simultaneously expressing five P450 enzymes for the screening of hepatotoxicity: identification of bioactivable drugs and the potential mechanism of toxicity involved.

scientific article published on 9 February 2013

High-content screening of drug-induced mitochondrial impairment in hepatic cells: effects of statins

scientific article published on 27 August 2014

Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.

scientific article published on 4 May 2016

LC-MS untargeted metabolomic analysis of drug-induced hepatotoxicity in HepG2 cells.

scientific article published in June 2015

Long-term and mechanistic evaluation of drug-induced liver injury in Upcyte human hepatocytes

scientific article published on 13 November 2018

Potential Impact of Steatosis on Cytochrome P450 Enzymes of Human Hepatocytes Isolated from Fatty Liver Grafts

scientific article published on 08 June 2006

Transcriptional regulation and expression of CYP3A4 in hepatocytes.

scientific article published on February 2007