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List of works by Markus Grube

Acute exposure to doxorubicin results in increased cardiac P-glycoprotein expression

scientific journal article

Antibody-dependent transplacental transfer of malaria blood-stage antigen using a human ex vivo placental perfusion model

scientific article

Beta‐Amyloid Downregulates MDR1‐P‐Glycoprotein (Abcb1) Expression at the Blood‐Brain Barrier in Mice ⬇️

scientific article published on May 29, 2011

Busulfan induces activin A expression in vitro and in vivo: a possible link to venous occlusive disease

scientific article published on September 2003

Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.

scientific article published in September 2004

Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5).

scientific article

Changes of myocardial gene expression and protein composition in patients with dilated cardiomyopathy after immunoadsorption with subsequent immunoglobulin substitution

scientific article published on 13 July 2016

Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals

scientific article

Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.

scientific article

Doxorubicin enhances oxysterol levels resulting in a LXR-mediated upregulation of cardiac cholesterol transporters.

scientific article published on 11 August 2017

Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil

scientific article published on 7 October 2010

Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).

scientific article published on 13 January 2006

Expression of ABC-type transport proteins in human platelets

scientific article published in June 2010

Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival

scientific article published on 24 February 2009

Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy

scientific article published on 8 August 2016

Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy

scientific article published on January 2007

Expression of drug transporters and drug metabolizing enzymes in the bladder urothelium in man and affinity of the bladder spasmolytic trospium chloride to transporters likely involved in its pharmacokinetics.

scientific article published on 10 December 2014

Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation

scientific article

Expression, localization, and function of the carnitine transporter octn2 (slc22a5) in human placenta.

scientific article

Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.

scientific article published on 20 April 2010

Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin

scientific article published on 23 February 2009

Increased lysyl oxidase expression and collagen cross-linking during atrial fibrillation ⬇️

scientific article published on January 6, 2011

Involvement of AP-2 binding sites in regulation of human beta-glucuronidase

scientific article

Lack of P-glycoprotein Results in Impairment of Removal of Beta-Amyloid and Increased Intraparenchymal Cerebral Amyloid Angiopathy after Active Immunization in a Transgenic Mouse Model of Alzheimer's Disease

scientific article published on December 2016

MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier

scientific article

Modification of OATP2B1-mediated transport by steroid hormones

scientific article

Organic anion transporting polypeptide 2B1 and breast cancer resistance protein interact in the transepithelial transport of steroid sulfates in human placenta.

scientific article published on 4 October 2006

Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart

scientific article

Organic cation transporter 3: expression in failing and nonfailing human heart and functional characterization

scientific article published on October 2011

Overexpression of glutathione S-transferase A1-1 in ECV 304 cells protects against busulfan mediated G2-arrest and induces tissue factor expression

scientific article published on December 2002

Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation

scientific article published in February 2010

Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.

scientific article

Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy

scientific article

St. John's Wort reduces beta-amyloid accumulation in a double transgenic Alzheimer's disease mouse model-role of P-glycoprotein

scientific article published on 28 June 2013

Steroid hormones specifically modify the activity of organic anion transporting polypeptides.

scientific article

The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers

scientific article

The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy

scientific article published in November 2007

Uptake of cardiovascular drugs into the human heart: expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5).

scientific article published on 20 February 2006

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