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List of works by Christophe Vanpouille

A common anti-cytomegalovirus drug, ganciclovir, inhibits HIV-1 replication in human tissues ex vivo

scientific article published on July 2017

A highly sensitive and dynamic immunofluorescent cytometric bead assay for the detection of HIV-1 p24.

scientific article published on 6 January 2009

A multi-targeted drug candidate with dual anti-HIV and anti-HSV activity

scientific article (publication date: 2013)

A new antiviral: chimeric 3TC-AZT phosphonate efficiently inhibits HIV-1 in human tissues ex vivo.

scientific article

A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2

scientific article

Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.

scientific article published on 8 February 2007

Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues

scientific article

Acyclovir: a new use for an old drug

scientific article published on December 2009

An ex vivo Model of HIV-1 Infection in Human Lymphoid Tissue and Cervico-vaginal Tissue

scientific article published on January 2014

Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60

scientific article

Cervico-vaginal tissue ex vivo as a model to study early events in HIV-1 infection

scientific article published on 12 January 2011

Coinfecting viruses as determinants of HIV disease

scientific article

Contrasting roles for TLR ligands in HIV-1 pathogenesis

scientific article

Design, synthesis and biological evaluation of phosphorodiamidate prodrugs of antiviral and anticancer nucleosides

scientific article

Distinct cytokine/chemokine network in semen and blood characterize different stages of HIV infection

scientific article published on 10 November 2015

Dual-targeted anti-TB/anti-HIV heterodimers

scientific article

Evolution of SIV toward RANTES resistance in macaques rapidly progressing to AIDS upon coinfection with HHV-6A.

scientific article published on 2 July 2009

Exploiting the anti-HIV-1 activity of acyclovir: suppression of primary and drug-resistant HIV isolates and potentiation of the activity by ribavirin

scientific article published on 6 February 2012

Extracellular Vesicles Carry HIV Env and Facilitate Hiv Infection of Human Lymphoid Tissue

scientific article

Genital Cytomegalovirus Replication Predicts Syphilis Acquisition among HIV-1 Infected Men Who Have Sex with Men.

scientific article published on 10 June 2015

HIV Trafficking Between Blood and Semen During Early Untreated HIV Infection.

scientific article published on 11 August 2016

HIV-1 imposes rigidity on blood and semen cytokine networks

scientific article published on 24 September 2012

HIV-1 induced activation of CD4+ T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo

scientific article published in October 2007

HIV-1 vaginal transmission: cell-free or cell-associated virus?

scientific article published on 15 April 2014

Histocultures (tissue explants) in human retrovirology

scientific article published in January 2014

Human cytomegalovirus-infected cells release extracellular vesicles that carry viral surface proteins

Interaction with glycosaminoglycans is required for cyclophilin B to trigger integrin-mediated adhesion of peripheral blood T lymphocytes to extracellular matrix

scientific article

Interactions between human immunodeficiency virus type 1 and vaccinia virus in human lymphoid tissue ex vivo

scientific article

Interleukin-7 facilitates HIV-1 transmission to cervico-vaginal tissue ex vivo

scientific article

Involvement of GAGs in the activity of pro-inflammatory factors.

scientific article published on January 2003

Long-term changes of serum chemokine levels in vaccinated military personnel

scientific article published on 11 September 2006

Mechanisms associated with HIV-1 resistance to acyclovir by the V75I mutation in reverse transcriptase

scientific article published on 09 June 2009

Microbicides: still a long road to success ⬇️

scientific article published on June 15, 2012

Monocytes but Not Lymphocytes Carrying HIV-1 on Their Surface Transmit Infection to Human Tissue Ex Vivo.

scientific article published on 24 August 2016

Novel approach to inhibit asthma-mediated lung inflammation using anti-CD147 intervention

scientific article

Octasaccharide is the minimal length unit required for efficient binding of cyclophilin B to heparin and cell surface heparan sulphate.

scientific article

Oxadiazols: a new class of rationally designed anti-human immunodeficiency virus compounds targeting the nuclear localization signal of the viral matrix protein

scientific article

Semen of HIV-1-infected individuals: local shedding of herpesviruses and reprogrammed cytokine network

scientific article published on 22 November 2011

Standardization of a cytometric p24-capture bead-assay for the detection of main HIV-1 subtypes

scientific article published on 22 January 2016

The application of phosphoramidate protide technology to acyclovir confers anti-HIV inhibition.

scientific article published on September 2009

The heparin/heparan sulfate sequence that interacts with cyclophilin B contains a 3-O-sulfated N-unsubstituted glucosamine residue.

scientific article

Topical tenofovir, a microbicide effective against HIV, inhibits herpes simplex virus-2 replication

scientific article

Vaginal Lactobacillus Inhibits HIV-1 Replication in Human Tissues Ex Vivo

scientific article published on 19 May 2017

Valacyclovir Decreases Plasma HIV-1 RNA in HSV-2 Seronegative Individuals: A Randomized Placebo-Controlled Crossover Trial

scientific article published on 3 March 2015

Viral interactions in human lymphoid tissue: Human herpesvirus 7 suppresses the replication of CCR5-tropic human immunodeficiency virus type 1 via CD4 modulation

scientific article published on 25 October 2006

Virtual screening of acyclovir derivatives as potential antiviral agents: design, synthesis and biological evaluation of new acyclic nucleoside ProTides

scientific article

War and peace between microbes: HIV-1 interactions with coinfecting viruses

scientific article

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