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List of works by Hongping Dong

2'-O methylation of internal adenosine by flavivirus NS5 methyltransferase

scientific article

2'-O methylation of the viral mRNA cap evades host restriction by IFIT family members

scientific journal article

A multidimensional platform for the purification of non-coding RNA species

scientific article published on August 2013

A translation inhibitor that suppresses dengue virus in vitro and in vivo

scientific article

Biochemical and genetic characterization of dengue virus methyltransferase

scientific article

Characterization of dengue virus NS4A and NS4B protein interaction

scientific article

Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings

scientific article

Crystal structure of dengue virus methyltransferase without S-adenosyl-L-methionine

scientific article

Determinants of Dengue Virus NS4A Protein Oligomerization

scientific article published on April 2015

Dimerization of flavivirus NS4B protein

scientific article published on 03 January 2014

Discovery of Dengue Virus NS4B Inhibitors

scientific article published on 27 May 2015

Distinct RNA Elements Confer Specificity to Flavivirus RNA Cap Methylation Events

scientific article

Evasion of early innate immune response by 2'-O-methylation of dengue genomic RNA.

scientific article published on 04 October 2016

Flavivirus RNA cap methyltransferase: structure, function, and inhibition ⬇️

scientific article published on August 1, 2010

Flavivirus RNA methylation

scientific article published on 31 January 2014

Flavivirus methyltransferase: a novel antiviral target

scientific article published on 05 June 2008

Functional analysis of two cavities in flavivirus NS5 polymerase

scientific article

Genetic Interactions among the West Nile Virus Methyltransferase, the RNA-Dependent RNA Polymerase, and the 5' Stem-Loop of Genomic RNA

scientific article

Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus

scientific article published on 29 March 2010

Identification and characterization of inhibitors of West Nile virus

scientific article

Potent Allosteric Dengue Virus NS5 Polymerase Inhibitors: Mechanism of Action and Resistance Profiling

scientific article

RNA structures required for production of subgenomic flavivirus RNA

scientific article (publication date: November 2010)

Rational Design of a Flavivirus Vaccine by Abolishing Viral RNA 2′- O Methylation ⬇️

scientific article published on March 13, 2013

Rational design of a live attenuated dengue vaccine: 2'-o-methyltransferase mutants are highly attenuated and immunogenic in mice and macaques

scientific article

Separate molecules of West Nile virus methyltransferase can independently catalyze the N7 and 2′-O methylations of viral RNA cap

scientific article

Small Molecule Inhibitors That Selectively Block Dengue Virus Methyltransferase

scientific article

Stabilization of dengue virus polymerase in de novo initiation assay provides advantages for compound screening

scientific article published on 18 April 2015

Strategies for development of Dengue virus inhibitors

scientific article

Structure and Function of Flavivirus NS5 Methyltransferase

scientific article (publication date: April 2007)

Ten years of dengue drug discovery: progress and prospects

scientific article published on 27 September 2013

The role of sequence context, nucleotide pool balance and stress in 2'-deoxynucleotide misincorporation in viral, bacterial and mammalian RNA.

scientific article published on 30 June 2016

West Nile Virus 5'-Cap Structure Is Formed by Sequential Guanine N-7 and Ribose 2'-O Methylations by Nonstructural Protein 5

scientific article

West Nile Virus Methyltransferase Catalyzes Two Methylations of the Viral RNA Cap through a Substrate-Repositioning Mechanism

scientific article

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