List of works - Mårten Fryknäs

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

scientific article

Large-Scale Gene Expression Profiling Platform for Identification of Context-Dependent Drug Responses in Multicellular Tumor Spheroids

scientific article (publication date: November 2016)

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system ⬇️

scientific article published on April 2, 2012

Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity

scientific article

Novel activity of acriflavine against colorectal cancer tumor cells

scientific article

Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment

scientific article

Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model

scientific article published in August 2006

Piperlongumine induces inhibition of the ubiquitin-proteasome system in cancer cells

scientific article published on 11 January 2013

Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

scientific article

STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines

scientific article published on January 2007

Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

scientific article

Screening of an annotated compound library for drug activity in a resistant myeloma cell line

scientific article

Targeting tumor cells based on Phosphodiesterase 3A expression

scientific article

The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation

scientific article

Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer

scientific article published on 24 April 2015

Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects

scientific article published on 28 October 2017

List of works by Mårten Fryknäs

Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments

Large-Scale Gene Expression Profiling Platform for Identification of Context-Dependent Drug Responses in Multicellular Tumor Spheroids

Loss of cancer drug activity in colon cancer HCT-116 cells during spheroid formation in a new 3-D spheroid cell culture system ⬇️

Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition

Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity

Novel activity of acriflavine against colorectal cancer tumor cells

Phenotype-based drug screening in primary ovarian carcinoma cultures identifies intracellular iron depletion as a promising strategy for cancer treatment

Phenotype-based screening of mechanistically annotated compounds in combination with gene expression and pathway analysis identifies candidate drug targets in a human squamous carcinoma cell model

Piperlongumine induces inhibition of the ubiquitin-proteasome system in cancer cells

Repositioning of the anthelmintic drug mebendazole for the treatment for colon cancer

STAT1 signaling is associated with acquired crossresistance to doxorubicin and radiation in myeloma cell lines

Screening for phenotype selective activity in multidrug resistant cells identifies a novel tubulin active agent insensitive to common forms of cancer drug resistance

Screening of an annotated compound library for drug activity in a resistant myeloma cell line

Targeting tumor cells based on Phosphodiesterase 3A expression

The anticancer effect of mebendazole may be due to M1 monocyte/macrophage activation via ERK1/2 and TLR8-dependent inflammasome activation

Three-Dimensional Cell Culture-Based Screening Identifies the Anthelmintic Drug Nitazoxanide as a Candidate for Treatment of Colorectal Cancer

Towards repositioning of quinacrine for treatment of acute myeloid leukemia - Promising synergies and in vivo effects