List of works - Tomasz Sewastianik

A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

scientific article published on 01 March 2021

A novel β-catenin/BCL9 complex inhibitor blocks oncogenic Wnt signaling and disrupts cholesterol homeostasis in colorectal cancer

scientific article published on 29 April 2022

A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia.

scientific article published on 30 March 2018

Aggressive CD4/CD8 Double-Negative Primary Cutaneous T-Cell Lymphoma With Dural Invasion: A Rare Presentation of Mycosis Fungoides?

scientific article published on 14 July 2020

BCL9 provides multi-cellular communication properties in colorectal cancer by interacting with paraspeckle proteins

scientific article published on 07 January 2020

Bortezomib induces anti-multiple myeloma immune response mediated by cGAS/STING pathway activation

scientific article published on 23 April 2021

Constitutive Ras signaling and Ink4a/Arf inactivation cooperate during the development of B-ALL in mice

scientific article published on 21 November 2017

Expression of PIM kinases in Reed-Sternberg cells fosters immune privilege and tumor cell survival in Hodgkin lymphoma.

scientific article published on 11 July 2017

FOXO1 activation is an effector of SYK and AKT inhibition in tonic BCR signal-dependent diffuse large B-cell lymphomas.

scientific article published on 19 November 2015

FOXO1 is a TXN- and p300-dependent sensor and effector of oxidative stress in diffuse large B-cell lymphomas characterized by increased oxidative metabolism

scientific article

Human MYD88L265P is insufficient by itself to drive neoplastic transformation in mature mouse B cells

scientific article published on 01 November 2019

Inhibition of ATM blocks the etoposide-induced DNA damage response and apoptosis of resting human T cells.

scientific article published on 9 October 2012

MEK Inhibition Sensitizes Precursor B-Cell Acute Lymphoblastic Leukemia (B-ALL) Cells to Dexamethasone through Modulation of mTOR Activity and Stimulation of Autophagy

scientific article

MYC deregulation in lymphoid tumors: molecular mechanisms, clinical consequences and therapeutic implications

scientific article published on 06 September 2014

MiR-17-92 represses PTPROt and PP2A phosphatases and amplifies tonic BCR signaling in DLBCL cells.

scientific article published on 06 October 2016

Microenvironment-induced PIM kinases promote CXCR4-triggered mTOR pathway required for chronic lymphocytic leukaemia cell migration.

scientific article published on 17 April 2018

Multicenter phase 2 study of daratumumab monotherapy in patients with previously treated Waldenström macroglobulinemia

scientific article published on 01 October 2020

Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy.

scientific article published on 29 January 2018

ROBO1 Promotes Homing, Dissemination, and Survival of Multiple Myeloma within the Bone Marrow Microenvironment

Transaminase Inhibition by 2-Hydroxyglutarate Impairs Glutamate Biosynthesis and Redox Homeostasis in Glioma

scientific article published on 13 September 2018

List of works by Tomasz Sewastianik