List of works - Jörg Timm

A genotype independent, full-genome reverse-transcription protocol for HCV genotyping and resistance testing

scientific article published on 10 April 2017

A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice

scientific article

Absence of viral escape within a frequently recognized HLA-A26-restricted CD8+ T-cell epitope targeting the functionally constrained hepatitis C virus NS5A/5B cleavage site

scientific article published in July 2007

Acute hepatitis C virus infection induces anti-host cell receptor antibodies with virus-neutralizing properties

scientific article published on 23 May 2015

Amino acid substitutions within HLA-B*27-restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8+ T cells.

scientific article

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level

scientific article

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level

scientific article published in May 2011

Assessing the risk of CMV reactivation and reconstitution of antiviral immune response post bone marrow transplantation by the QuantiFERON-CMV-assay and real time PCR.

scientific article published on 9 January 2018

CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins

scientific article published on 2 March 2011

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

scientific article published on 2 July 2018

Clinical outcome and viral genome variability of hepatitis B virus induced acute liver failure (HEP-18-0579)

scientific article published on 11 February 2019

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation

scientific article

Daclatasvir, Simeprevir and Ribavirin as a Promising Interferon-Free Triple Regimen for HCV Recurrence after Liver Transplant

scientific article

Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant

scientific article

Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure

scientific article published on 8 June 2017

Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection

scientific article published in October 2017

Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.

scientific article published on 9 November 2011

Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R

scientific article published on 01 August 2019

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents

scientific article

Genotypic resistance testing of HCV - is there a clinical need?

scientific article published on 4 August 2016

HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope

scientific article published on 23 August 2013

HLA-Bw4 80(T) and multiple HLA-Bw4 copies combined with KIR3DL1 associate with spontaneous clearance of HCV infection in people who inject drugs.

scientific article published on 12 April 2017

Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies

scientific article

Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe.

scientific article published on 22 April 2015

Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells

scientific article published on 9 July 2014

Liver transplantation from HCV RNA-positive donors in the era of interferon-free HCV therapeutics: a re-examination of the situation

scientific article published on 8 November 2016

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

scientific article

Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection

scientific article

Management of telaprevir-based triple therapy for hepatitis C virus recurrence post liver transplant

scientific article published on May 2015

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8 T Cells and Evolve at the Population Level

scientific article published on 12 February 2019

Natural prevalence of resistance-associated variants in hepatitis C virus NS5A in genotype 3a-infected people who inject drugs in Germany

scientific article published on 8 July 2015

Phenotype and function of HBV-specific T cells is determined by the targeted epitope in addition to the stage of infection.

scientific article published on 22 December 2018

Pre-exposure prophylaxis failure with tenofovir disoproxil.

scientific article published on January 2017

Prevalence of hepatitis E virus infection in pediatric solid organ transplant recipients--a single-center experience

scientific article published on 28 June 2012

Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells

scientific article published on 05 September 2019

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

scientific article

Role of BK polyomavirus (BKV) and Torque teno virus (TTV) in liver transplant recipients with renal impairment

scientific article published on 23 August 2018

SEC14L2, a lipid-binding protein, regulate HCV replication in culture with inter- and intra- genotype variations

article

SEC14L2, a lipid-binding protein, regulates HCV replication in culture with inter- and intra-genotype variations

article

SeqFeatR for the Discovery of Feature-Sequence Associations

scientific article published on 5 January 2016

Serine protease inhibitors as anti-hepatitis C virus agents

scientific article published on June 2009

Susceptibility to chronic hepatitis C virus infection is influenced by sequence differences in immunodominant CD8+ T cell epitopes ⬇️

scientific article published on August 25, 2012

The influence of immunosuppressants on direct-acting antiviral therapy is dependent on hepatitis C virus genotype

scientific article published on 7 November 2017

The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation

article

Transplantation of Renal Allografts From Organ Donors Reactive for HCV Antibodies to HCV-Negative Recipients: Safety and Clinical Outcome.

scientific article

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

scientific article published on June 2008

[Prophylaxis, diagnosis and therapy of hepatitis-C-virus (HCV) infection: the German guidelines on the management of HCV infection - AWMF-Register-No.: 021/012]

scientific article published on 26 June 2018

List of works by Jörg Timm

A genotype independent, full-genome reverse-transcription protocol for HCV genotyping and resistance testing

A polymorphism near IL28B is associated with spontaneous clearance of acute hepatitis C virus and jaundice

Absence of viral escape within a frequently recognized HLA-A26-restricted CD8+ T-cell epitope targeting the functionally constrained hepatitis C virus NS5A/5B cleavage site

Acute hepatitis C virus infection induces anti-host cell receptor antibodies with virus-neutralizing properties

Amino acid substitutions within HLA-B*27-restricted T cell epitopes prevent recognition by hepatitis delta virus-specific CD8+ T cells.

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level

Analysis of the Evolutionary Forces in an Immunodominant CD8 Epitope in Hepatitis C Virus at a Population Level

Assessing the risk of CMV reactivation and reconstitution of antiviral immune response post bone marrow transplantation by the QuantiFERON-CMV-assay and real time PCR.

CD8+ T-cell response promotes evolution of hepatitis C virus nonstructural proteins

CEACAM1 promotes CD8+ T cell responses and improves control of a chronic viral infection.

Clinical outcome and viral genome variability of hepatitis B virus induced acute liver failure (HEP-18-0579)

Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation

Daclatasvir, Simeprevir and Ribavirin as a Promising Interferon-Free Triple Regimen for HCV Recurrence after Liver Transplant

Daily low-dose tacrolimus is a safe and effective immunosuppressive regimen during telaprevir-based triple therapy for hepatitis C virus recurrence after liver transplant

Detection of a genetic footprint of the sofosbuvir resistance-associated substitution S282T after HCV treatment failure

Early Transcriptional Divergence Marks Virus-Specific Primary Human CD8+ T Cells in Chronic versus Acute Infection

Escape from a dominant HLA-B*15-restricted CD8+ T cell response against hepatitis C virus requires compensatory mutations outside the epitope.

Failure of Dolutegravir First-Line ART with Selection of Virus Carrying R263K and G118R

Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents

Genotypic resistance testing of HCV - is there a clinical need?

HLA-B*27 subtype specificity determines targeting and viral evolution of a hepatitis C virus-specific CD8+ T cell epitope

HLA-Bw4 80(T) and multiple HLA-Bw4 copies combined with KIR3DL1 associate with spontaneous clearance of HCV infection in people who inject drugs.

Hepatitis C virus hypervariable region 1 variants presented on hepatitis B virus capsid-like particles induce cross-neutralizing antibodies

Hepatitis E Virus Infection as a Possible Cause of Acute Liver Failure in Europe.

Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells

Liver transplantation from HCV RNA-positive donors in the era of interferon-free HCV therapeutics: a re-examination of the situation

Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27–restricted human immune response

Lymphocytes Negatively Regulate NK Cell Activity via Qa-1b following Viral Infection

Management of telaprevir-based triple therapy for hepatitis C virus recurrence post liver transplant

Mutations in Hepatitis D Virus Allow It to Escape Detection by CD8 T Cells and Evolve at the Population Level

Natural prevalence of resistance-associated variants in hepatitis C virus NS5A in genotype 3a-infected people who inject drugs in Germany

Phenotype and function of HBV-specific T cells is determined by the targeted epitope in addition to the stage of infection.

Pre-exposure prophylaxis failure with tenofovir disoproxil.

Prevalence of hepatitis E virus infection in pediatric solid organ transplant recipients--a single-center experience

Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells

Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope

Role of BK polyomavirus (BKV) and Torque teno virus (TTV) in liver transplant recipients with renal impairment

SEC14L2, a lipid-binding protein, regulate HCV replication in culture with inter- and intra- genotype variations

SEC14L2, a lipid-binding protein, regulates HCV replication in culture with inter- and intra-genotype variations

SeqFeatR for the Discovery of Feature-Sequence Associations

Serine protease inhibitors as anti-hepatitis C virus agents

Susceptibility to chronic hepatitis C virus infection is influenced by sequence differences in immunodominant CD8+ T cell epitopes ⬇️

The influence of immunosuppressants on direct-acting antiviral therapy is dependent on hepatitis C virus genotype

The predictive value of IL28B gene polymorphism for spontaneous clearance in a single source outbreak cohort is limited in patients carrying the CCR5Δ32 mutation

Transplantation of Renal Allografts From Organ Donors Reactive for HCV Antibodies to HCV-Negative Recipients: Safety and Clinical Outcome.

Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection

[Prophylaxis, diagnosis and therapy of hepatitis-C-virus (HCV) infection: the German guidelines on the management of HCV infection - AWMF-Register-No.: 021/012]