List of works - Rosa Angela Cardone

A novel NHE1-centered signaling cassette drives epidermal growth factor receptor-dependent pancreatic tumor metastasis and is a target for combination therapy.

scientific article

Assessment of different 3D culture systems to study tumor phenotype and chemosensitivity in pancreatic ductal adenocarcinoma

scientific article published on 10 May 2016

Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1.

scientific article published on July 2008

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

scientific article

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases.

scientific article published on 10 February 2017

Corrigendum: Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome

scientific article published on 28 August 2019

Erratum: Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question.

scientific article published on 18 December 2014

Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension

scientific article

Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine

scientific article published on 22 December 2020

Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome.

scientific article

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

scientific article

NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains

scientific article

Na+/H+ exchanger regulatory factor 1 expression levels in blood and tissue predict breast tumour clinical behaviour

scientific article published on 01 June 2011

Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells

scientific article

Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibro

scientific article published on 3 October 2005

Paclitaxel induces apoptosis via protein kinase A- and p38 mitogen-activated protein-dependent inhibition of the Na+/H+ exchanger (NHE) NHE isoform 1 in human breast cancer cells

scientific article published on June 2003

Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism

scientific article published on 13 October 2018

Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.

scientific article published on 13 December 2013

Protons extruded by NHE1: digestive or glue?

scientific article published on 06 March 2008

RhoA protein expression in primary breast cancers and matched lymphocytes is associated with progression of the disease

scientific article published on 01 July 2008

Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response

scientific article published on 28 October 2020

Role of pHi, and proton transporters in oncogene-driven neoplastic transformation

scientific article published on 03 February 2014

The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

scientific article

The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

scientific article published on 22 February 2019

The Role of Sodium Hydrogen Exchanger 1 in Dysregulation of Proton Dynamics and Reprogramming of Cancer Metabolism as a Sequela

scientific article published on 28 July 2019

The scaffolding protein NHERF1 sensitizes EGFR-dependent tumor growth, motility and invadopodia function to gefitinib treatment in breast cancer cells.

scientific article published on 19 December 2014

List of works by Rosa Angela Cardone

A novel NHE1-centered signaling cassette drives epidermal growth factor receptor-dependent pancreatic tumor metastasis and is a target for combination therapy.

Assessment of different 3D culture systems to study tumor phenotype and chemosensitivity in pancreatic ductal adenocarcinoma

Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1.

Cariporide and other new and powerful NHE1 inhibitors as potentially selective anticancer drugs--an integral molecular/biochemical/metabolic/clinical approach after one hundred years of cancer research

Cellular acidification as a new approach to cancer treatment and to the understanding and therapeutics of neurodegenerative diseases.

Corrigendum: Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome

Erratum: Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question.

Exhaled and arterial levels of endothelin-1 are increased and correlate with pulmonary systolic pressure in COPD with pulmonary hypertension

Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine

Extracellular matrix composition modulates PDAC parenchymal and stem cell plasticity and behavior through the secretome.

Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question

NHERF1 acts as a molecular switch to program metastatic behavior and organotropism via its PDZ domains

Na+/H+ exchanger regulatory factor 1 expression levels in blood and tissue predict breast tumour clinical behaviour

Na+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cells

Na+/H+ exchanger regulatory factor isoform 1 overexpression modulates cystic fibrosis transmembrane conductance regulator (CFTR) expression and activity in human airway 16HBE14o- cells and rescues DeltaF508 CFTR functional expression in cystic fibro

Paclitaxel induces apoptosis via protein kinase A- and p38 mitogen-activated protein-dependent inhibition of the Na+/H+ exchanger (NHE) NHE isoform 1 in human breast cancer cells

Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism

Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.

Protons extruded by NHE1: digestive or glue?

RhoA protein expression in primary breast cancers and matched lymphocytes is associated with progression of the disease

Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response

Role of pHi, and proton transporters in oncogene-driven neoplastic transformation

The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells

The Possible Role of Helicobacter pylori in Gastric Cancer and Its Management

The Role of Sodium Hydrogen Exchanger 1 in Dysregulation of Proton Dynamics and Reprogramming of Cancer Metabolism as a Sequela

The scaffolding protein NHERF1 sensitizes EGFR-dependent tumor growth, motility and invadopodia function to gefitinib treatment in breast cancer cells.