List of works - Felipe Diaz-Griffero

A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction

scientific article published on 05 August 2009

A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen

scientific article

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.

scientific article

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies

scientific article

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells

scientific article

BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid

scientific article

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding

scientific article published on 30 June 2006

Chromatin organization at the nuclear pore favours HIV replication

scientific article

Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp

scientific article

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

scientific article published on 29 June 2015

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

scientific article

Contribution of MxB oligomerization to HIV-1 capsid binding and restriction

scientific article

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.

scientific article

Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.

scientific article published on 16 October 2012

Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration.

scientific article published on 19 December 2013

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

scientific article

Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility.

scientific article

Endocytosis is a critical step in entry of subgroup B avian leukosis viruses.

scientific article

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

scientific article

HIV-1 uncoating is facilitated by dynein and kinesin 1

scientific article

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

scientific article

Identification and characterization of naturally occurring splice variants of SAMHD1

scientific article

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1

scientific article

Inhibition of reverse transcriptase activity increases stability of the HIV-1 core

scientific article published on 17 October 2012

Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particles

scientific article

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.

scientific article published on 18 December 2017

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain

scientific article

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

scientific article

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

scientific article published on 21 March 2013

Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection

scientific article

Preferential lentiviral targeting of astrocytes in the central nervous system

scientific article

Proceedings of the Frontiers of Retrovirology Conference 2016.

scientific article published on 26 September 2016

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

scientific article published on 23 July 2015

RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating

scientific article published on 23 November 2011

Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.

scientific article

Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.

scientific article published on 2 May 2006

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

scientific article published on 10 June 2015

Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region.

scientific article

Retroviral restriction factor TRIM5alpha is a trimer

scientific article

Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core

scientific article

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac ⬇️

scientific article published on June 12, 2012

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

scientific article published on 10 February 2016

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

scientific article

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

scientific article

Structure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition module

scientific article

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

scientific article

TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity

scientific article published on 22 September 2005

The Role of TNPO3 in HIV-1 Replication ⬇️

scientific article published on July 19, 2012

The ability of multimerized cyclophilin A to restrict retrovirus infection

scientific article

The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha

scientific article published on 15 May 2005

The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating

scientific article

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

scientific article

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

scientific journal article

Trafficking of some old world primate TRIM5α proteins through the nucleus ⬇️

scientific article published on May 15, 2011

Unique features of TRIM5alpha among closely related human TRIM family members

scientific article

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.

scientific article

List of works by Felipe Diaz-Griffero

A B-box 2 surface patch important for TRIM5alpha self-association, capsid binding avidity, and retrovirus restriction

A novel aminoacid determinant of HIV-1 restriction in the TRIM5α variable 1 region isolated in a random mutagenic screen

A proteolytic cascade controls lysosome rupture and necrotic cell death mediated by lysosome-destabilizing adjuvants.

A rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmies

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells

BI-2 destabilizes HIV-1 cores during infection and Prevents Binding of CPSF6 to the HIV-1 Capsid

Characterization of TRIM5alpha trimerization and its contribution to human immunodeficiency virus capsid binding

Chromatin organization at the nuclear pore favours HIV replication

Comparative requirements for the restriction of retrovirus infection by TRIM5alpha and TRIMCyp

Complement-Opsonized HIV-1 Overcomes Restriction in Dendritic Cells.

Contribution of E3-ubiquitin ligase activity to HIV-1 restriction by TRIM5alpha(rh): structure of the RING domain of TRIM5alpha

Contribution of MxB oligomerization to HIV-1 capsid binding and restriction

Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1.

Contribution of SUMO-interacting motifs and SUMOylation to the antiretroviral properties of TRIM5α.

Correction: Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration.

Ebselen, a Small-Molecule Capsid Inhibitor of HIV-1 Replication.

Effects of human SAMHD1 polymorphisms on HIV-1 susceptibility.

Endocytosis is a critical step in entry of subgroup B avian leukosis viruses.

HIV-1 capsids bind and exploit the kinesin-1 adaptor FEZ1 for inward movement to the nucleus

HIV-1 uncoating is facilitated by dynein and kinesin 1

Human nucleoporins promote HIV-1 docking at the nuclear pore, nuclear import and integration

Identification and characterization of naturally occurring splice variants of SAMHD1

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1

Inhibition of reverse transcriptase activity increases stability of the HIV-1 core

Lentivirus display: stable expression of human antibodies on the surface of human cells and virus particles

Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.

Modulation of retroviral restriction and proteasome inhibitor-resistant turnover by changes in the TRIM5alpha B-box 2 domain

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

Nup153 and Nup98 bind the HIV-1 core and contribute to the early steps of HIV-1 replication.

Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection

Preferential lentiviral targeting of astrocytes in the central nervous system

Proceedings of the Frontiers of Retrovirology Conference 2016.

RING Dimerization Links Higher-Order Assembly of TRIM5α to Synthesis of K63-Linked Polyubiquitin.

RING domain mutations uncouple TRIM5α restriction of HIV-1 from inhibition of reverse transcription and acceleration of uncoating

Rapid turnover and polyubiquitylation of the retroviral restriction factor TRIM5.

Requirements for capsid-binding and an effector function in TRIMCyp-mediated restriction of HIV-1.

Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal

Restriction of HIV-1 by rhesus TRIM5α is governed by alpha helices in the Linker2 region.

Retroviral restriction factor TRIM5alpha is a trimer

Rhesus monkey TRIM5α SPRY domain recognizes multiple epitopes that span several capsid monomers on the surface of the HIV-1 mature viral core

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac ⬇️

SUN2 Overexpression Deforms Nuclear Shape and Inhibits HIV.

Specific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factor

Structural basis of HIV-1 capsid recognition by PF74 and CPSF6.

Structure of the rhesus monkey TRIM5 PRYSPRY domain, the HIV capsid recognition module

TNPO3 is required for HIV-1 replication after nuclear import but prior to integration and binds the HIV-1 core

TRIM5alpha association with cytoplasmic bodies is not required for antiretroviral activity

The Role of TNPO3 in HIV-1 Replication ⬇️

The ability of multimerized cyclophilin A to restrict retrovirus infection

The contribution of RING and B-box 2 domains to retroviral restriction mediated by monkey TRIM5alpha

The fate of HIV-1 capsid: a biochemical assay for HIV-1 uncoating

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

Trafficking of some old world primate TRIM5α proteins through the nucleus ⬇️

Unique features of TRIM5alpha among closely related human TRIM family members

dNTP pool modulation dynamics by SAMHD1 protein in monocyte-derived macrophages.