List of works - Dominique Mazier

1,3,5-Triazepane-2,6-diones as structurally diverse and conformationally constrained dipeptide mimetics: identification of malaria liver stage inhibitors from a small pilot library

scientific article published in November 2006

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

scientific article

A mouse model for Candida glabrata hematogenous disseminated infection starting from the gut: evaluation of strains with different adhesion properties

scientific article (publication date: 2013)

A plant-derived morphinan as a novel lead compound active against malaria liver stages

scientific article

A pre-emptive strike against malaria's stealthy hepatic forms

scientific article

A rapid and robust selection procedure for generating drug-selectable marker-free recombinant malaria parasites

scientific article published on 23 April 2014

A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites

scientific article (publication date: 5 March 2004)

A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites

scientific article

A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial

scientific article

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates

scientific article published on 16 February 2012

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage ⬇️

scientific article

Chronic malaria revealed by a new fluorescence pattern on the antinuclear autoantibodies test

scientific article

Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co-cultured with Plasmodium falciparum field isolates

scientific article

Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, France, 2011-2013

scientific article published on May 2015

Deletion of T cells bearing the V beta8.1 T-cell receptor following mouse mammary tumor virus 7 integration confers resistance to murine cerebral malaria

scientific article

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

scientific article published on 10 March 2015

Easy identification of leishmania species by mass spectrometry

scientific article

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

scientific article

Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.

scientific article published on 21 May 2007

Hepatitis C virus infection may lead to slower emergence of P. falciparum in blood

scientific article

Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

scientific article (publication date: 2003)

Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain

scientific article published in February 2008

Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection

scientific article published on September 2008

IgE Mediates Killing of Intracellular Toxoplasma gondii by Human Macrophages through CD23-Dependent, Interleukin-10 Sensitive Pathway ⬇️

scientific article published on April 22, 2011

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

scientific article (publication date: 9 December 2011)

Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers.

scientific article published on June 2017

Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria

scientific article

Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations

scientific article (publication date: 4 March 2011)

Isolation and antimalarial activity of new morphinan alkaloids on Plasmodium yoelii liver stage.

scientific article

Laser capture microdissection of hepatic stages of the human parasite Plasmodium falciparum for molecular analysis

scientific article published in January 2005

MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole

scientific article

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites

scientific article published on 29 August 2015

Multilocus phylogeny and MALDI-TOF analysis of the plant pathogenic species Alternaria dauci and relatives

scientific article

P. falciparum isolate-specific distinct patterns of induced apoptosis in pulmonary and brain endothelial cells

scientific article

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

scientific article published on 9 February 2014

Plasmodium P36 determines host cell receptor usage during sporozoite invasion

scientific article

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites

scientific article (publication date: 23 February 2016)

Plasmodium falciparum clearance is rapid and pitting independent in immune Malian children treated with artesunate for malaria

scientific article

Postartesunate delayed hemolysis is a predictable event related to the lifesaving effect of artemisinins

scientific article

Pseudallescheria/Scedosporium complex species identification by Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry

scientific article

Rapid species diagnosis for invasive candidiasis using mass spectrometry ⬇️

scientific article

Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice

scientific article

Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection

scientific article

Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria

scientific article published on 19 December 2012

Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy

scientific article

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

scientific article

Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection

scientific article

The Ig domain protein CD9P-1 down-regulates CD81 ability to support Plasmodium yoelii infection

scientific article

The N'-terminal domain of glyceraldehyde-3-phosphate dehydrogenase of the apicomplexan Plasmodium falciparum mediates GTPase Rab2-dependent recruitment to membranes

scientific article (publication date: August 2003)

The Plasmodium sporozoite survives RTS,S vaccination

scientific article published in October 2005

The impact of lowering the cut-off value on the sensitivity of the Platelia Elisa IgG (Bio-Rad) test for toxoplasmosis diagnosis

scientific article

The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro.

scientific article

Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery

scientific article

Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development

scientific article (publication date: May 2014)

Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage

scientific article published on December 2008

List of works by Dominique Mazier

1,3,5-Triazepane-2,6-diones as structurally diverse and conformationally constrained dipeptide mimetics: identification of malaria liver stage inhibitors from a small pilot library

A genetically attenuated malaria vaccine candidate based on P. falciparum b9/slarp gene-deficient sporozoites

A mouse model for Candida glabrata hematogenous disseminated infection starting from the gut: evaluation of strains with different adhesion properties

A plant-derived morphinan as a novel lead compound active against malaria liver stages

A pre-emptive strike against malaria's stealthy hepatic forms

A rapid and robust selection procedure for generating drug-selectable marker-free recombinant malaria parasites

A role for apical membrane antigen 1 during invasion of hepatocytes by Plasmodium falciparum sporozoites

A role for immune responses against non-CS components in the cross-species protection induced by immunization with irradiated malaria sporozoites

A virosomal malaria peptide vaccine elicits a long-lasting sporozoite-inhibitory antibody response in a phase 1a clinical trial

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates

Atorvastatin prevents Plasmodium falciparum cytoadherence and endothelial damage ⬇️

Chronic malaria revealed by a new fluorescence pattern on the antinuclear autoantibodies test

Comparison of apoptosis in human primary pulmonary endothelial cells and a brain microvascular endothelial cell line co-cultured with Plasmodium falciparum field isolates

Delayed-onset hemolytic anemia in patients with travel-associated severe malaria treated with artesunate, France, 2011-2013

Deletion of T cells bearing the V beta8.1 T-cell receptor following mouse mammary tumor virus 7 integration confers resistance to murine cerebral malaria

Discovery of new thienopyrimidinone derivatives displaying antimalarial properties toward both erythrocytic and hepatic stages of Plasmodium

Easy identification of leishmania species by mass spectrometry

Gene disruption of Plasmodium falciparum p52 results in attenuation of malaria liver stage development in cultured primary human hepatocytes

Genetically attenuated P36p-deficient Plasmodium berghei sporozoites confer long-lasting and partial cross-species protection.

Hepatitis C virus infection may lead to slower emergence of P. falciparum in blood

Hepatocyte CD81 is required for Plasmodium falciparum and Plasmodium yoelii sporozoite infectivity

Hepatocyte permissiveness to Plasmodium infection is conveyed by a short and structurally conserved region of the CD81 large extracellular domain

Host scavenger receptor SR-BI plays a dual role in the establishment of malaria parasite liver infection

IgE Mediates Killing of Intracellular Toxoplasma gondii by Human Macrophages through CD23-Dependent, Interleukin-10 Sensitive Pathway ⬇️

Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug Discovery

Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers.

Inhibition of Plasmodium falciparum field isolates-mediated endothelial cell apoptosis by Fasudil: therapeutic implications for severe malaria

Inhibitory effect of TNF-α on malaria pre-erythrocytic stage development: influence of host hepatocyte/parasite combinations

Isolation and antimalarial activity of new morphinan alkaloids on Plasmodium yoelii liver stage.

Laser capture microdissection of hepatic stages of the human parasite Plasmodium falciparum for molecular analysis

MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole

Multidrug ATP-binding cassette transporters are essential for hepatic development of Plasmodium sporozoites

Multilocus phylogeny and MALDI-TOF analysis of the plant pathogenic species Alternaria dauci and relatives

P. falciparum isolate-specific distinct patterns of induced apoptosis in pulmonary and brain endothelial cells

Persistence and activation of malaria hypnozoites in long-term primary hepatocyte cultures

Plasmodium P36 determines host cell receptor usage during sporozoite invasion

Plasmodium falciparum PfSET7: enzymatic characterization and cellular localization of a novel protein methyltransferase in sporozoite, liver and erythrocytic stage parasites

Plasmodium falciparum clearance is rapid and pitting independent in immune Malian children treated with artesunate for malaria

Postartesunate delayed hemolysis is a predictable event related to the lifesaving effect of artemisinins

Pseudallescheria/Scedosporium complex species identification by Matrix-Assisted Laser Desorption Ionization Time-Of-Flight Mass Spectrometry

Rapid species diagnosis for invasive candidiasis using mass spectrometry ⬇️

Recombinant human IFN-alpha inhibits cerebral malaria and reduces parasite burden in mice

Scavenger receptor BI boosts hepatocyte permissiveness to Plasmodium infection

Skin-draining lymph node priming is sufficient to induce sterile immunity against pre-erythrocytic malaria

Specific targeting of caspase-9/PP2A interaction as potential new anti-cancer therapy

Sterile protection against malaria is independent of immune responses to the circumsporozoite protein

Temperature shift and host cell contact up-regulate sporozoite expression of Plasmodium falciparum genes involved in hepatocyte infection

The Ig domain protein CD9P-1 down-regulates CD81 ability to support Plasmodium yoelii infection

The N'-terminal domain of glyceraldehyde-3-phosphate dehydrogenase of the apicomplexan Plasmodium falciparum mediates GTPase Rab2-dependent recruitment to membranes

The Plasmodium sporozoite survives RTS,S vaccination

The impact of lowering the cut-off value on the sensitivity of the Platelia Elisa IgG (Bio-Rad) test for toxoplasmosis diagnosis

The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro.

Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery

Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development

Vaccination with live Plasmodium yoelii blood stage parasites under chloroquine cover induces cross-stage immunity against malaria liver stage