List of works - Serena Spudich

641Acute Retroviral Syndrome is Associated with Gut Mucosal CD4 Depletion, Inflammation and High Viral and Proviral Burden in Systemic and Tissue Compartments.

scientific article published in December 2014

Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments

scientific article published on 7 December 2017

Amyloid and tau cerebrospinal fluid biomarkers in HIV infection

scientific article

An example of genetically distinct HIV type 1 variants in cerebrospinal fluid and plasma during suppressive therapy.

scientific article published on 12 December 2013

Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection

scientific article published on 13 August 2013

Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients

scientific article published on 08 September 2020

Blood-Brain Barrier Disruption Is Initiated During Primary HIV Infection and Not Rapidly Altered by Antiretroviral Therapy

scientific article published on 29 March 2017

Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden

scientific article published in September 2011

Central nervous system viral invasion and inflammation during acute HIV infection

scientific article

Cerebral white matter integrity during primary HIV infection

scientific article published on February 2015

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders

article

Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection

scientific article

Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load ⬇️

scientific article published on September 10, 2012

Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection

scientific article published on 4 March 2013

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy ⬇️

scientific article published on May 10, 2013

Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection

scientific article

Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection

scientific article

Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection

scientific article published on 16 December 2009

Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1-associated dementia

scientific article

Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection

scientific article

Corrigendum to: "Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study" [EBioMedicine 3 (216) 135-140].

scientific article published on 20 April 2016

Defining and evaluating HIV-related neurodegenerative disease and its treatment targets: a combinatorial approach to use of cerebrospinal fluid molecular biomarkers

scientific article published on 12 September 2006

Evolving character of chronic central nervous system HIV infection

scientific article

HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types ⬇️

scientific article published on October 6, 2011

HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment

scientific article

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection

scientific article published on 07 February 2017

Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.

scientific article published on 2 November 2016

Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers

scientific article published on 28 March 2016

Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy

scientific article

Longitudinal characterization of depression and mood states beginning in primary HIV infection

scientific article published in June 2014

Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV

scientific article published on 10 November 2015

Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy

scientific article

Peripheral neuropathy in primary HIV infection associates with systemic and central nervous system immune activation

scientific article

Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy

scientific article published on February 2008

Phenotypic Correlates of HIV-1 Macrophage Tropism

scientific article published on 2 September 2015

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study

scientific article published on 22 November 2015

Potential for early antiretroviral therapy to reduce central nervous system HIV-1 persistence

scientific article published on 01 December 2019

Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection

scientific article

Putamen volume and its clinical and neurological correlates in primary HIV infection

scientific article published on 31 March 2016

Raltegravir treatment intensification does not alter cerebrospinal fluid HIV-1 infection or immunoactivation in subjects on suppressive therapy

scientific article published on 21 October 2011

Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic

scientific article published on 31 July 2020

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection

scientific article published on January 2016

List of works by Serena Spudich

641Acute Retroviral Syndrome is Associated with Gut Mucosal CD4 Depletion, Inflammation and High Viral and Proviral Burden in Systemic and Tissue Compartments.

Acute Retroviral Syndrome is Associated with High Viral Burden, CD4 Depletion, and Immune Activation in Systemic and Tissue Compartments

Amyloid and tau cerebrospinal fluid biomarkers in HIV infection

An example of genetically distinct HIV type 1 variants in cerebrospinal fluid and plasma during suppressive therapy.

Approach to cerebrospinal fluid (CSF) biomarker discovery and evaluation in HIV infection

Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients

Blood-Brain Barrier Disruption Is Initiated During Primary HIV Infection and Not Rapidly Altered by Antiretroviral Therapy

Central nervous system immune activation characterizes primary human immunodeficiency virus 1 infection even in participants with minimal cerebrospinal fluid viral burden

Central nervous system viral invasion and inflammation during acute HIV infection

Cerebral white matter integrity during primary HIV infection

Cerebrospinal Fluid Concentrations of the Synaptic Marker Neurogranin in Neuro-HIV and Other Neurological Disorders

Cerebrospinal fluid (CSF) neuronal biomarkers across the spectrum of HIV infection: hierarchy of injury and detection

Cerebrospinal fluid HIV escape associated with progressive neurologic dysfunction in patients on antiretroviral therapy with well controlled plasma viral load ⬇️

Cerebrospinal fluid and neuroimaging biomarker abnormalities suggest early neurological injury in a subset of individuals during primary HIV infection

Cerebrospinal fluid neopterin decay characteristics after initiation of antiretroviral therapy ⬇️

Cerebrospinal fluid neopterin: an informative biomarker of central nervous system immune activation in HIV-1 infection

Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection

Compartmentalization and clonal amplification of HIV-1 variants in the cerebrospinal fluid during primary infection

Compartmentalized human immunodeficiency virus type 1 originates from long-lived cells in some subjects with HIV-1-associated dementia

Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection

Corrigendum to: "Plasma concentration of the neurofilament light protein (NFL) is a biomarker of CNS injury in HIV infection: A cross-sectional study" [EBioMedicine 3 (216) 135-140].

Defining and evaluating HIV-related neurodegenerative disease and its treatment targets: a combinatorial approach to use of cerebrospinal fluid molecular biomarkers

Evolving character of chronic central nervous system HIV infection

HIV-1 Replication in the Central Nervous System Occurs in Two Distinct Cell Types ⬇️

HIV-1 viral escape in cerebrospinal fluid of subjects on suppressive antiretroviral treatment

High Number of Activated CD8+ T Cells Targeting HIV Antigens Are Present in Cerebrospinal Fluid in Acute HIV Infection

Immediate initiation of cART is associated with lower levels of cerebrospinal fluid YKL-40, a marker of microglial activation, in HIV-1 infection.

Immune Activation and HIV-Specific CD8(+) T Cells in Cerebrospinal Fluid of HIV Controllers and Noncontrollers

Immune activation of the central nervous system is still present after >4 years of effective highly active antiretroviral therapy

Longitudinal characterization of depression and mood states beginning in primary HIV infection

Neurological Response to cART vs. cART plus Integrase Inhibitor and CCR5 Antagonist Initiated during Acute HIV

Neuropsychological Impairment in Acute HIV and the Effect of Immediate Antiretroviral Therapy

Peripheral neuropathy in primary HIV infection associates with systemic and central nervous system immune activation

Persistent intrathecal immune activation in HIV-1-infected individuals on antiretroviral therapy

Phenotypic Correlates of HIV-1 Macrophage Tropism

Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study

Potential for early antiretroviral therapy to reduce central nervous system HIV-1 persistence

Progressive increase in central nervous system immune activation in untreated primary HIV-1 infection

Putamen volume and its clinical and neurological correlates in primary HIV infection

Raltegravir treatment intensification does not alter cerebrospinal fluid HIV-1 infection or immunoactivation in subjects on suppressive therapy

Stroke Code Presentations, Interventions, and Outcomes Before and During the COVID-19 Pandemic

Virological and immunological characteristics of HIV-infected individuals at the earliest stage of infection