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List of works by Kazuhide Iwasaki

A newly developed DNA microarray is useful to assess induction of cytochromes p450 in the cynomolgus monkey.

scientific article

Assessment of multiple cytochrome P450 activities in metabolically inactivated human liver microsomes and roles of P450 2C isoforms in reaction phenotyping studies

scientific article

Comparison of cytochrome P450 3A enzymes in cynomolgus monkeys and humans

scientific article published on January 2010

Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase

scientific article published on 06 May 2015

Cytochrome P450 metabolic activities in the small intestine of cynomolgus macaques bred in Cambodia, China, and Indonesia.

scientific article

Evaluation of 23 Lots of Commercially Available Cryopreserved Hepatocytes for Induction Assays of Human Cytochromes P450

scientific article published on 19 February 2014

Evaluation of 89 compounds for identification of substrates for cynomolgus monkey CYP2C76, a new bupropion/nifedipine oxidase

scientific article published on 15 October 2014

Expression of cytochromes p450 in fetal, infant, and juvenile liver of cynomolgus macaques.

scientific article published on 16 August 2011

Expression profile of hepatic genes in cynomolgus macaques bred in Cambodia, China, and Indonesia: implications for cytochrome P450 genes.

scientific article

Identification of putative substrates for cynomolgus monkey cytochrome P450 2C8 by substrate depletion assays with 22 human P450 substrates and inhibitors

scientific article published on 18 November 2015

In vivo individual variations in pharmacokinetics of efavirenz in cynomolgus monkeys genotyped for cytochrome P450 2C9.

scientific article published on 15 July 2016

Macaque cytochromes P450: nomenclature, transcript, gene, genomic structure, and function.

scientific article published on 09 February 2011

Monkey liver cytochrome P450 2C19 is involved in R- and S-warfarin 7-hydroxylation

scientific article published on 03 October 2012

Monkey liver cytochrome P450 2C9 is involved in caffeine 7-N-demethylation to form theophylline

scientific article published on 16 May 2013

Newly identified CYP2C93 is a functional enzyme in rhesus monkey, but not in cynomolgus monkey

scientific article

Similar substrate specificity of cynomolgus monkey cytochrome P450 2C19 to reported human P450 2C counterpart enzymes by evaluation of 89 drug clearances

scientific article published on 8 September 2015

Simultaneous pharmacokinetics assessment of caffeine, warfarin, omeprazole, metoprolol, and midazolam intravenously or orally administered to Microminipigs

scientific article

Slow R-warfarin 7-hydroxylation mediated by P450 2C19 genetic variants in cynomolgus monkeys in vivo.

scientific article

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