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List of works by Branden S Moriarity

1,2-GG intrastrand cross-link of antitumor dinuclear bifunctional platinum compound with spermidine linker inhibits DNA polymerization more effectively than the cross-link of conventional cisplatin.

scientific article published on 06 December 2006

A Comprehensive Guide to Sleeping Beauty-Based Somatic Transposon Mutagenesis in the Mouse

scientific article

A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma

scientific article

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis

scientific article published on 11 May 2015

A novel role for SALL4 during scar-free wound healing in axolotl.

scientific article published on 8 December 2016

CRISPR/Cas9 Genetic Modification of CYP3A5 *3 in HuH-7 Human Hepatocyte Cell Line Leads to Cell Lines with Increased Midazolam and Tacrolimus Metabolism

scientific article

CRISPR/Cas9 library screening for drug target discovery

scientific article published on 20 November 2017

CRISPR/Cas9-Mediated Genome Engineering of Primary Human B Cells

scientific article published on 01 January 2020

Canonical Wnt/β-catenin signaling drives human schwann cell transformation, progression, and tumor maintenance

scientific article published on 27 March 2013

Comparative transcriptome analysis quantifies immune cell transcript levels, metastatic progression and survival in osteosarcoma.

scientific article published on 24 October 2017

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST.

scientific article published on 18 December 2012

Coping with cancer genes altered by copy number

scientific article published on November 2015

EditR: A Method to Quantify Base Editing from Sanger Sequencing

scientific article published on 01 June 2018

Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells

scientific article published on 02 October 2011

Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis

scientific article published on 13 June 2019

Engineering of Primary Human B cells with CRISPR/Cas9 Targeted Nuclease

scientific article published in Scientific Reports

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

scientific article published on 19 May 2013

Highly multiplexed genome engineering using CRISPR/Cas9 gRNA arrays

scientific article published in PLoS ONE

HomeRun Vector Assembly System: a flexible and standardized cloning system for assembly of multi-modular DNA constructs

scientific article

Identification of candidate neoantigens produced by fusion transcripts in human osteosarcomas

scientific article published in Scientific Reports

Implication of ZNF217 in accelerating tumor development and therapeutically targeting ZNF217-induced PI3K-AKT signaling for the treatment of metastatic osteosarcoma

scientific article published on 30 September 2020

Modular assembly of transposon integratable multigene vectors using RecWay assembly.

scientific article published on 26 February 2013

PCM-15SOMATIC CRISPR/Cas9-MEDIATED TUMOR SUPPRESSOR DISRUPTION ENABLES VERSATILE BRAIN TUMOR MODELING.

scientific article

PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma

scientific article published on 03 April 2020

PM-05ARHGAP36 AS A NOVEL DRIVER IN HIGH-RISK HUMAN MEDULLOBLASTOMA.

scientific article published in November 2014

PTPS-02FOXR2: AN ONCOGENE IN MEDULLOBLASTOMA.

scientific article

PVT1 dependence in cancer with MYC copy-number increase.

scientific article published on 22 June 2014

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

scientific article published on 02 August 2016

Prosurvival long noncoding RNA PINCR regulates a subset of p53 targets in human colorectal cancer cells by binding to Matrin 3

scientific article

RALB provides critical survival signals downstream of Ras in acute myeloid leukemia

scientific article published on 20 August 2016

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

scientific article

Rapid generation of Col7a1-/- mouse model of recessive dystrophic epidermolysis bullosa and partial rescue via immunosuppressive dermal mesenchymal stem cells

scientific article published on 11 September 2017

Relative importance of βcyto- and γcyto-actin in primary mouse embryonic fibroblasts

scientific article published on 11 January 2017

SEMA4C is a novel target to limit osteosarcoma growth, progression, and metastasis

Sex bias occurrence of hepatocellular carcinoma in Poly7 molecular subclass is associated with EGFR.

scientific article

Simple and efficient methods for enrichment and isolation of endonuclease modified cells

scientific article (publication date: 2014)

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma

scientific article published on 24 October 2018

Sleeping Beauty transposon insertional mutagenesis based mouse models for cancer gene discovery

scientific article published on February 2015

Slit-Robo GTPase-Activating Protein 2 as a metastasis suppressor in osteosarcoma.

scientific article published on 14 December 2016

Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

scientific article published on 11 June 2015

The Molecular Imaging of Natural Killer Cells

scholarly article published in Molecular imaging : official journal of the Society for Molecular Imaging

The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14.

scientific article published on March 2016

Transposon mouse models to elucidate the genetic mechanisms of hepatitis B viral induced hepatocellular carcinoma.

scientific article

Trp53 haploinsufficiency modifies EGFR-driven peripheral nerve sheath tumorigenesis

scientific article

Using RNA-seq and targeted nucleases to identify mechanisms of drug resistance in acute myeloid leukemia

scientific article

Using genome-wide CRISPR library screening with library resistant DCK to find new sources of Ara-C drug resistance in AML

scientific article

mTORC1 Coordinates Protein Synthesis and Immunoproteasome Formation via PRAS40 to Prevent Accumulation of Protein Stress

scientific article published on 10 February 2016

microRNA-based attenuation of influenza virus across susceptible hosts

scientific article published in November 2017

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