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List of works by Perry B Hackett

A transposon and transposase system for human application

scientific article

Awakening gene therapy with Sleeping Beauty transposons

scientific article

Characterization of the Human Artemis Promoter by Heterologous Gene Expression In Vitro and In Vivo ⬇️

scientific article published on June 10, 2011

Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.

scientific article published on April 2009

Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon

scientific article published on 26 June 2006

Counterselection and co-delivery of transposon and transposase functions for Sleeping Beauty-mediated transposition in cultured mammalian cells

scientific article published on December 2004

DDE transposases: Structural similarity and diversity

scientific article

Delivering the second revolution in site-specific nucleases

scientific article

Duration of expression and activity of Sleeping Beauty transposase in mouse liver following hydrodynamic DNA delivery

scientific article

Editing livestock genomes with site-specific nucleases

scientific article published on January 2013

Effective Expression-Independent Gene Trapping and Mutagenesis Mediated by Sleeping Beauty Transposon ⬇️

scientific article published on August 23, 2012

Effective Gene Trapping Mediated by Sleeping Beauty Transposon ⬇️

scientific article published on August 31, 2012

Efficacy and Safety of Sleeping Beauty Transposon-Mediated Gene Transfer in Preclinical Animal Studies ⬇️

scientific article published on October 1, 2011

Efficient nonmeiotic allele introgression in livestock using custom endonucleases

scientific article published on 06 September 2013

Engineered Swine Models of Cancer

scientific article

Evaluating risks of insertional mutagenesis by DNA transposons in gene therapy ⬇️

scientific article published on January 10, 2013

Fishing for answers with transposons.

scientific article

Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons

scientific article

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

scientific article published in September 2003

Gene therapy for neurologic manifestations of mucopolysaccharidoses

scientific article

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

scientific article

Harnessing a high cargo-capacity transposon for genetic applications in vertebrates

scientific article published on 28 August 2006

Human hepatic stellate cell line (LX-2) exhibits characteristics of bone marrow-derived mesenchymal stem cells.

scientific article published on 9 September 2011

Infusing CD19-directed T cells to augment disease control in patients undergoing autologous hematopoietic stem-cell transplantation for advanced B-lymphoid malignancies.

scientific article

Lysosomal storage disease: gene therapy on both sides of the blood-brain barrier

scientific article

Mammalian germ-line transgenesis by transposition.

scientific article

Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis

scientific article

NMR structural analysis ofSleeping Beautytransposase binding to DNA

scientific article

Phase I trials using Sleeping Beauty to generate CD19-specific CAR T cells

scientific article published on 02 August 2016

Precision Editing of Large Animal Genomes ⬇️

scientific article published on January 1, 2012

Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy

scientific article

Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

scientific article

Prolonged Expression of Secreted Enzymes in Dogs After Liver-Directed Delivery of Sleeping Beauty Transposons: Implications for Non-Viral Gene Therapy of Systemic Disease

scientific article published on 20 May 2017

Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses

scientific article

Quantitative analysis of α-L-iduronidase expression in immunocompetent mice treated with the Sleeping Beauty transposon system

scientific article

Redirecting specificity of T-cell populations for CD19 using the Sleeping Beauty system

scientific article published on April 2008

Sleeping Beauty System to Redirect T-cell Specificity for Human Applications ⬇️

scientific article published on February 1, 2013

Sleeping Beauty-mediated correction of Fanconi anemia type C.

scientific article

Sleeping Beauty-mediated transposition and long-term expression in vivo: use of the LoxP/Cre recombinase system to distinguish transposition-specific expression

scientific article published on 13 December 2005

Sleeping beauty transposon-mediated gene therapy for prolonged expression

scientific article

Structure-based prediction of insertion-site preferences of transposons into chromosomes

scientific article

Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon

scientific article

Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system

scientific article

Targeting DNA With Fingers and TALENs ⬇️

scientific article published on January 24, 2012

The Sleeping Beauty transposon system: a non-viral vector for gene therapy ⬇️

scientific article published on April 15, 2011

Transgene expression and silencing in a tick cell line: A model system for functional tick genomics

scientific article

Translating Sleeping Beauty transposition into cellular therapies: victories and challenges

scientific article

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

scientific article

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