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List of works by Isabelle Malet

Association of Gag cleavage sites to protease mutations and to virological response in HIV-1 treated patients

scientific article published on 26 July 2006

Characterization and structural analysis of HIV-1 integrase conservation

scientific article published on January 2009

Clonal analyses of HIV quasispecies in patients harbouring plasma genotype with K65R mutation associated with thymidine analogue mutations or L74V substitution

scientific article published in March 2005

Combination of two pathways involved in raltegravir resistance confers dolutegravir resistance

scientific article published on 23 July 2015

Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes

scientific article published on 23 May 2014

Differential impact of APOBEC3-driven mutagenesis on HIV evolution in diverse anatomical compartments

scientific article published on February 2014

E138K and M184I mutations in HIV-1 reverse transcriptase coemerge as a result of APOBEC3 editing in the absence of drug exposure

scientific article published in August 2012

E17A mutation in HIV-1 Vpr confers resistance to didanosine in association with thymidine analog mutations

scientific article published on 25 November 2011

Factors associated with proviral DNA HIV-1 tropism in antiretroviral therapy-treated patients with fully suppressed plasma HIV viral load: implications for the clinical use of CCR5 antagonists

scientific article

Genetic barriers for integrase inhibitor drug resistance in HIV type-1 B and CRF02_AG subtypes

scientific article

HIV-1 genome is often defective in PBMCs and rectal tissues after long-term HAART as a result of APOBEC3 editing and correlates with the size of reservoirs

scientific article published on 11 June 2012

Highly multidrug-resistant HIV: clonal analysis and therapeutic strategies

scientific article published on 19 July 2013

Impact of gag mutations on selection of darunavir resistance mutations in HIV-1 protease

scientific article published in September 2008

Mutations Located outside the Integrase Gene Can Confer Resistance to HIV-1 Integrase Strand Transfer Inhibitors

scientific article published on 26 September 2017

Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro

scientific article published on 28 January 2008

New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors

scientific article published on 7 April 2014

Partially active HIV-1 Vif alleles facilitate viral escape from specific antiretrovirals

scientific article published on September 2010

Pathway involving the N155H mutation in HIV-1 integrase leads to dolutegravir resistance

scientific article published on 24 January 2018

Phenotypic analysis of HIV-1 E157Q integrase polymorphism and impact on virological outcome in patients initiating an integrase inhibitor-based regimen

scientific article published on 12 January 2018

Presence of HIV-1 R5 viruses in cerebrospinal fluid even in patients harboring R5X4/X4 viruses in plasma

scientific article

Prevalence of resistance mutations related to integrase inhibitor S/GSK1349572 in HIV-1 subtype B raltegravir-naive and -treated patients

article

Primary genotypic resistance of HIV-1 to CCR5 antagonists in CCR5 antagonist treatment-naive patients

scientific article published in October 2008

Primary genotypic resistance of HIV-1 to the maturation inhibitor PA-457 in protease inhibitor-experienced patients

scientific article published in April 2007

Quasispecies variant dynamics during emergence of resistance to raltegravir in HIV-1-infected patients

scientific article published on 16 February 2009

Raltegravir has no residual antiviral activity in vivo against HIV-1 with resistance-associated mutations to this drug

scientific article published on 27 August 2009

Reply to Das and Berkhout, "How Polypurine Tract Changes in the HIV-1 RNA Genome Can Cause Resistance against the Integrase Inhibitor Dolutegravir".

scientific article published on 29 May 2018

Resistance-associated mutations to etravirine (TMC-125) in antiretroviral-naïve patients infected with non-B HIV-1 subtypes

scientific article published on 14 December 2009

Role of HIV-1 minority populations on resistance mutational pattern evolution and susceptibility to protease inhibitors

scientific article published in January 2006

Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors

scientific article published on 3 September 2010

The HIV-1 integrase G118R mutation confers raltegravir resistance to the CRF02_AG HIV-1 subtype.

scientific article published on 19 September 2011

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