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List of works by Roland Tubiana

A new mechanism of resistance of HIV-2 to integrase inhibitors: a 5 amino-acids insertion in the integrase C-terminal domain

article

Antiretroviral therapy with a twice-daily regimen containing 400 milligrams of indinavir and 100 milligrams of ritonavir in human immunodeficiency virus type 1-infected women during pregnancy

scientific article published on 4 February 2008

Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma

article

Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma on a 2002-2011 survey

scientific article published in May 2012

Determinants of a Low CD4/CD8 Ratio in HIV-1-Infected Individuals Despite Long-term Viral Suppression

scientific article

Differential impact of APOBEC3-driven mutagenesis on HIV evolution in diverse anatomical compartments

scientific article published on February 2014

Direct quantification of cell-associated HIV DNA in isolated rectal and blood memory CD4 T cells revealed their similar and low infection levels in long-term treated HIV-infected patients

scientific article published in March 2013

Discordance Between Cerebral Spinal Fluid and Plasma HIV Replication in Patients with Neurological Symptoms Who Are Receiving Suppressive Antiretroviral Therapy

article

Dolutegravir in HIV-2-Infected Patients With Resistant Virus to First-line Integrase Inhibitors From the French Named Patient Program

scientific article published on 17 February 2015

Dual therapy with lamivudine + protease inhibitor during pregnancy for prevention of mother-to-child transmission of HIV-1.

scientific article

Effect of antiretroviral drugs on the quality of semen

scientific article published in August 2011

Evidence of genotypic resistance diversity of archived and circulating viral strains in blood and semen of pre-treated HIV-infected men.

scientific article published on February 2004

Factors associated with a low HIV reservoir in patients with prolonged suppressive antiretroviral therapy

scientific article

Factors associated with proviral DNA HIV-1 tropism in antiretroviral therapy-treated patients with fully suppressed plasma HIV viral load: implications for the clinical use of CCR5 antagonists

scientific article

First line raltegravir/emtricitabine/tenofovir combination in HIV-2 infection: phase 2 non-comparative trial (ANRS 159 HIV-2).

scientific article published on 24 March 2018

Genetic diversity and drug resistance mutations in HIV type 1 from untreated patients in Bamako, Mali

scientific article published in January 2007

Greater viral rebound and reduced time to resume antiretroviral therapy after therapeutic immunization with the ALVAC-HIV vaccine (vCP1452)

article

HIV genetic diversity between plasma and cerebrospinal fluid in patients with HIV encephalitis

article

HIV-1 or hepatitis C chronic infection in serodiscordant infertile couples has no impact on infertility treatment outcome

scientific article published on 3 September 2009

HIV-2 X4 tropism is associated with lower CD4+ cell count in treatment-experienced patients

scientific article published on September 2014

Highly multidrug-resistant HIV: clonal analysis and therapeutic strategies

scientific article published on 19 July 2013

Hot spots of integrase genotypic changes leading to HIV-2 resistance to raltegravir

scientific article

Immune and virological benefits of 10 years of permanent viral control with antiretroviral therapy

scientific article published in February 2010

Impact of gag mutations on selection of darunavir resistance mutations in HIV-1 protease

scientific article published in September 2008

Impact of hepatitis C and liver fibrosis on antiretroviral plasma drug concentrations in HIV-HCV co-infected patients: the HEPADOSE study

scientific article published on 2 September 2010

Increase of HIV-1 pro-viral DNA per million peripheral blood mononuclear cells in patients with advanced HIV disease (CD4<200 cells/mm3) receiving interleukin 2 combined with HAART versus HAART alone (ANRS-082 trial).

scientific article published in June 2003

Interruption of nonnucleoside reverse transcriptase inhibitor (NNRTI) therapy for 2 months has no effect on levels of human immunodeficiency virus type 1 in plasma of patients harboring viruses with mutations associated with resistance to NNRTIs

scientific article

Lopinavir/Ritonavir Monotherapy as a Nucleoside Analogue–Sparing Strategy to Prevent HIV-1 Mother-to-Child Transmission: The ANRS 135 PRIMEVA Phase 2/3 Randomized Trial ⬇️

scientific article published on June 12, 2013

Low frequency of HIV-1 tropism evolution in patients successfully treated for at least 2 years

article

Low-level HIV-1 viraemia in patients on HAART: risk factors and management in clinical practice

scientific article published on 28 April 2015

Minority resistant variants are also present in HIV-2-infected antiretroviral-naive patients

scientific article published on 3 February 2018

No perinatal HIV-1 transmission from women with effective antiretroviral therapy starting before conception

scientific article published on 21 July 2015

Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome

scientific article published on 19 September 2009

Pharmacokinetics, safety and efficacy of ritonavir-boosted atazanavir (300/100 mg once daily) in HIV-1-infected pregnant women

scientific article published on 20 January 2015

Presence of HIV-1 R5 viruses in cerebrospinal fluid even in patients harboring R5X4/X4 viruses in plasma

scientific article

Prevention of mother-to-child HIV transmission: similar access for sub-Sahara African immigrants and for French women?

scientific article published on July 2008

Primary genotypic resistance of HIV-1 to CCR5 antagonists in CCR5 antagonist treatment-naive patients

scientific article published in October 2008

Raltegravir as functional monotherapy leads to virological failure and drug resistance in highly treatment-experienced HIV-infected patients

scientific article published in July 2010

Raltegravir concentrations in the genital tract of HIV-1-infected women treated with a raltegravir-containing regimen (DIVA 01 study)

scientific article

Raltegravir has no residual antiviral activity in vivo against HIV-1 with resistance-associated mutations to this drug

scientific article published on 27 August 2009

Resistance mutations before and after tenofovir regimen failure in HIV-1 infected patients

scientific article published in July 2005

Role of HIV-1 minority populations on resistance mutational pattern evolution and susceptibility to protease inhibitors

scientific article published in January 2006

Treatment interruption in chronically HIV-infected patients with an ultralow HIV reservoir

scientific article

Very early ART resulting in the absence of HIV-1 antibodies and in a sustained undetectable plasma HIV-1-RNA and proviral-DNA in an HLA-B*5701 and Δ32 heterozygote HIV-1-infected patient was not associated with functional cure

scientific article published on 19 September 2014

Virologic outcome after switching from a nucleoside reverse transcriptase inhibitor to tenofovir in patients with undetectable HIV-1 RNA plasma level

scientific article

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