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List of works by Betsy T Kren

A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid.

scientific article published on 7 April 2005

A novel system for simultaneous in vivo tracking and biological assessment of leukemia cells and ex vivo generated leukemia-reactive cytotoxic T cells

scientific article published in June 2004

Administration of tauroursodeoxycholic acid (TUDCA) reduces apoptosis following myocardial infarction in rat.

scientific article

CK2 Molecular Targeting-Tumor Cell-Specific Delivery of RNAi in Various Models of Cancer.

scientific article published on 21 February 2017

CK2 targeted RNAi therapeutic delivered via malignant cell-directed tenfibgen nanocapsule: dose and molecular mechanisms of response in xenograft prostate tumors.

scientific article published on 20 August 2016

DNA methylation of Sleeping Beauty with transposition into the mouse genome

scientific article published in August 2005

Differential regulation of cyclin D1 and cell death by bile acids in primary rat hepatocytes

scientific article published on 12 April 2007

Double-stranded siRNA targeted to the huntingtin gene does not induce DNA methylation

scientific article published on October 2004

Emergence of protein kinase CK2 as a key target in cancer therapy

scientific article

Erythroid-specific expression of beta-globin by the sleeping beauty transposon for Sickle cell disease

scientific article published on 18 May 2007

Evaluation of a new high-dimensional miRNA profiling platform

scientific article published on 27 August 2009

Evaluation of protein kinase CK2 as a therapeutic target for squamous cell carcinoma of cats

scientific article published in August 2017

Gene repair and transposon-mediated gene therapy

scientific article

Gene repair in the new age of gene therapy

scientific article

Gene therapy and CVD: how near are we?

scientific article published on May 2004

Gene therapy as an alternative to liver transplantation

scientific article

Genomewide microRNA down-regulation as a negative feedback mechanism in the early phases of liver regeneration

scientific article

High-level genomic integration, epigenetic changes, and expression of sleeping beauty transgene

scientific article

Identification of microRNAs during rat liver regeneration after partial hepatectomy and modulation by ursodeoxycholic acid

scientific article

Immune characteristics correlating with HSV-1 immune control and effect of squaric acid dibutyl ester on immune characteristics of subjects with frequent herpes labialis episodes

article

In vivo application of non-viral vectors to the liver

scientific article

Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon

scientific article

Mechanism and efficacy of sub-50-nm tenfibgen nanocapsules for cancer cell-directed delivery of anti-CK2 RNAi to primary and metastatic squamous cell carcinoma.

scientific article

MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells.

scientific article

MicroRNAs identified in highly purified liver-derived mitochondria may play a role in apoptosis

scientific article

Modulation of nuclear steroid receptors by ursodeoxycholic acid inhibits TGF-beta1-induced E2F-1/p53-mediated apoptosis of rat hepatocytes.

scientific article

Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

scientific article published on 08 June 2009

Nanoencapsulated anti-CK2 small molecule drug or siRNA specifically targets malignant cancer but not benign cells

scientific article published on 12 October 2011

Nuclear translocation of UDCA by the glucocorticoid receptor is required to reduce TGF-beta1-induced apoptosis in rat hepatocytes

scientific journal article

Polysome trafficking of transcripts and microRNAs in regenerating liver after partial hepatectomy

scientific article

Preclinical evaluation of cyclin dependent kinase 11 and casein kinase 2 survival kinases as RNA interference targets for triple negative breast cancer therapy

scientific article

Protein kinase CK2 inhibition induces cell death via early impact on mitochondrial function.

scientific article

Short, single-stranded oligonucleotides mediate targeted nucleotide conversion using extracts from isolated liver mitochondria

scientific article

Site-specific base changes in the coding or promoter region of the human beta- and gamma-globin genes by single-stranded oligonucleotides

scientific article

Sleeping Beauty transposition in the mouse genome is associated with changes in DNA methylation at the site of insertion

scientific article published on 22 May 2006

Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference.

scientific article published on April 2005

Strategies for hepatic gene correction

scientific article

Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α' subunits reduces orthotopic xenograft prostate tumors in mice

scientific article published on 15 July 2011

Tenfibgen ligand nanoencapsulation delivers bi-functional anti-CK2 RNAi oligomer to key sites for prostate cancer targeting using human xenograft tumors in mice

scientific article

Tenfibgen-DMAT Nanocapsule Delivers CK2 Inhibitor DMAT to Prostate Cancer Xenograft Tumors Causing Inhibition of Cell Proliferation

scientific article

The application of DNA repair vectors to gene therapy

scientific article

Therapeutic Targeting of Protein Kinase CK2 Gene Expression in Feline Oral Squamous Cell Carcinoma: A Naturally Occurring Large-Animal Model of Head and Neck Cancer

scientific article published on 23 March 2017

Tumor-induced mechanical hyperalgesia involves CGRP receptors and altered innervation and vascularization of DsRed2 fluorescent hindpaw tumors

scientific article

Ursodeoxycholic acid modulates E2F-1 and p53 expression through a caspase-independent mechanism in transforming growth factor beta1-induced apoptosis of rat hepatocytes

scientific article published on 26 September 2003

β‐globin matrix attachment region improves stable genomic expression of the Sleeping beauty transposon

scientific article published on September 1, 2011