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List of works by Hilde M van der Schaar

A novel, broad-spectrum inhibitor of enterovirus replication that targets host cell factor phosphatidylinositol 4-kinase IIIβ.

scientific article published on 29 July 2013

ACBD3 Is an Essential Pan-enterovirus Host Factor That Mediates the Interaction between Viral 3A Protein and Cellular Protein PI4KB

scientific article published on 12 February 2019

Characterization of the early events in dengue virus cell entry by biochemical assays and single-virus tracking

scientific article

Cholesterol: fa(s)t-food for enterovirus genome replication.

scientific article published on 6 October 2013

Coronavirus hemagglutinin-esterase and spike proteins co-evolve for functional balance and optimal virion avidity

scientific article published on 06 April 2020

Coronavirus hemagglutinin-esterase and spike proteins coevolve for functional balance and optimal virion avidity

scientific article published on 29 September 2020

Coxsackievirus mutants that can bypass host factor PI4KIIIβ and the need for high levels of PI4P lipids for replication

scientific article

Differential effects of the putative GBF1 inhibitors Golgicide A and AG1478 on enterovirus replication

scientific article

Direct-acting antivirals and host-targeting strategies to combat enterovirus infections.

scientific article

Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells ⬇️

scientific article (publication date: December 2008)

Escaping Host Factor PI4KB Inhibition: Enterovirus Genomic RNA Replication in the Absence of Replication Organelles.

scientific article

Fat(al) attraction: Picornaviruses Usurp Lipid Transfer at Membrane Contact Sites to Create Replication Organelles

scientific article published on 22 March 2016

Fitness and virulence of a coxsackievirus mutant that can circumnavigate the need for phosphatidylinositol 4-kinase class III beta

scientific article

GBF1, a guanine nucleotide exchange factor for Arf, is crucial for coxsackievirus B3 RNA replication

scientific article published on 09 September 2009

GBF1- and ACBD3-independent recruitment of PI4KIIIβ to replication sites by rhinovirus 3A proteins

scientific article published on 19 November 2014

How antibodies alter the cell entry pathway of dengue virus particles in macrophages

scientific article

Human AdV-20-42-42, a Promising Novel Adenoviral Vector for Gene Therapy and Vaccine Product Development

scientific article published on 01 September 2021

Immature Dengue Virus: A Veiled Pathogen?

scientific article (publication date: 2010)

Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein

scientific article

Modulation of proteolytic polyprotein processing by coxsackievirus mutants resistant to inhibitors targeting phosphatidylinositol-4-kinase IIIβ or oxysterol binding protein

scientific article published on 9 October 2017

Modulation of the Host Lipid Landscape to Promote RNA Virus Replication: The Picornavirus Encephalomyocarditis Virus Converges on the Pathway Used by Hepatitis C Virus

scientific article published on 25 September 2015

Mutations in Encephalomyocarditis Virus 3A Protein Uncouple the Dependency of Genome Replication on Host Factors Phosphatidylinositol 4-Kinase IIIα and Oxysterol-Binding Protein

scientific article published on 11 May 2016

Origins of Enterovirus Replication Organelles Established by Whole-Cell Electron Microscopy

scientific article published on 11 June 2019

Recruitment of PI4KIIIβ to coxsackievirus B3 replication organelles is independent of ACBD3, GBF1, and Arf1.

scientific article

Role of antibodies in controlling dengue virus infection

scientific article published on 03 March 2009

Targeting of the hydrophobic metabolome by pathogens.

scientific article

The transformation of enterovirus replication structures: a three-dimensional study of single- and double-membrane compartments

scientific article

Tyrphostin AG1478 Inhibits Encephalomyocarditis Virus and Hepatitis C Virus by Targeting Phosphatidylinositol 4-Kinase IIIα.

scientific article published on August 2016

Uncovering oxysterol-binding protein (OSBP) as a target of the anti-enteroviral compound TTP-8307.

scientific article published on 11 January 2017

Viral reorganization of the secretory pathway generates distinct organelles for RNA replication

scientific article

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