List of works by Frank Bruchertseifer

177Lu-immunotherapy of experimental peritoneal carcinomatosis shows comparable effectiveness to 213Bi-immunotherapy, but causes toxicity not observed with 213Bi ⬇️

scientific article published on November 12, 2010

213Bi radioimmunotherapy with an anti-mCD138 monoclonal antibody in a murine model of multiple myeloma

scientific article published on September 2013

213Bi-Labeled Prostate-Specific Membrane Antigen-Targeting Agents Induce DNA Double-Strand Breaks in Prostate Cancer Xenografts

scientific article published on March 2017

213Bi-induced death of HSC45-M2 gastric cancer cells is characterized by G2 arrest and up-regulation of genes known to prevent apoptosis but induce necrosis and mitotic catastrophe

scientific article published on August 2007

213Bi-radioimmunotherapy defeats early-stage disseminated gastric cancer in nude mice

scientific article published on 11 June 2007

225Ac- and 213Bi-Substance P Analogues for Glioma Therapy

scientific article published on 01 March 2020

A Radiolabeled Fully Human Antibody to Human Aspartyl (Asparaginyl) β-Hydroxylase Is a Promising Agent for Imaging and Therapy of Metastatic Breast Cancer

scientific article published on March 2017

A fully human antibody to gp41 selectively eliminates HIV-infected cells that transmigrated across a model human blood brain barrier

scientific article published on 20 November 2015

Activity and Adverse Events of Actinium-225-PSMA-617 in Advanced Metastatic Castration-resistant Prostate Cancer After Failure of Lutetium-177-PSMA

scientific article published on 05 December 2020

Alpha-particle emitting 213Bi-anti-EGFR immunoconjugates eradicate tumor cells independent of oxygenation

scientific article published in 2013

Anti-prostate-specific membrane antigen liposomes loaded with 225Ac for potential targeted antivascular α-particle therapy of cancer

scientific article published on 12 December 2013

Antitumor immunity induced after α irradiation

scientific article

Assessment of 213Bi-anti-EGFR MAb treatment efficacy in malignant cancer cells with [1-13C]pyruvate and [18F]FDG.

scientific article published on 5 June 2019

Bismuth-213 and actinium-225 -- generator performance and evolving therapeutic applications of two generator-derived alpha-emitting radioisotopes

scientific article

Bismuth-213 radioimmunotherapy with C595 anti-MUC1 monoclonal antibody in an ovarian cancer ascites model

scientific article

Combination of Antiretroviral Drugs and Radioimmunotherapy Specifically Kills Infected Cells from HIV-Infected Individuals

scientific article published on 26 September 2016

Combining α-Radioimmunotherapy and Adoptive T Cell Therapy to Potentiate Tumor Destruction

scientific article published on 22 June 2015

Comparison of therapeutic efficacy and biodistribution of 213Bi- and 211At-labeled monoclonal antibody MX35 in an ovarian cancer model

scientific article published on 29 September 2011

DNA double strand breaks as predictor of efficacy of the alpha-particle emitter Ac-225 and the electron emitter Lu-177 for somatostatin receptor targeted radiotherapy

scientific article

Development and evaluation of peptidic ligands targeting tumour-associated urokinase plasminogen activator receptor (uPAR) for use in alpha-emitter therapy for disseminated ovarian cancer

scientific article

Differential gene expression triggered by highly cytotoxic alpha-emitter-immunoconjugates in gastric cancer cells

scientific article

Dual-Nuclide Radiopharmaceuticals for Positron Emission Tomography Based Dosimetry in Radiotherapy

scientific article

Effective treatment of ductal carcinoma in situ with a HER-2- targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer

scientific article published on 23 April 2016

Efficient formation of inert Bi-213 chelates by tetraphosphorus acid analogues of DOTA: towards improved alpha-therapeutics

scientific article published on 08 August 2018

Enhanced efficacy of combined 213Bi-DTPA-F3 and paclitaxel therapy of peritoneal carcinomatosis is mediated by enhanced induction of apoptosis and G2/M phase arrest

scientific article

Fractionated intravesical radioimmunotherapy with (213)Bi-anti-EGFR-MAb is effective without toxic side-effects in a nude mouse model of advanced human bladder carcinoma

scientific article published on 15 July 2015

Functionalized NaA nanozeolites labeled with (224,225)Ra for targeted alpha therapy

scientific article published on 31 October 2013

High molecular mass radioimmunoconjugates are promising for intraperitoneal α-emitter immunotherapy due to prolonged retention in the peritoneum

scientific article published on 3 March 2012

Immunoliposomal delivery of 213Bi for alpha-emitter targeting of metastatic breast cancer

scientific article

In Vitro comparison of 213Bi- and 177Lu-radiation for peptide receptor radionuclide therapy.

scientific article

In vitro evaluation of 225 Ac-DOTA-Substance P for targeted alpha therapy of glioblastoma multiforme.

scientific article published on 2 April 2018

Influence of tumour size on the efficacy of targeted alpha therapy with (213)Bi-[DOTA(0),Tyr(3)]-octreotate

scientific article

Intravesical alpha-radioimmunotherapy with 213Bi-anti-EGFR-mAb defeats human bladder carcinoma in xenografted nude mice

scientific article published on October 2009

Investigation of para-sulfonatocalix[n]arenes [n = 6, 8] as potential chelates for (230)U.

scientific article

Long-Term Toxicity of 213Bi-Labelled BSA in Mice

scientific article (publication date: 2016)

Microbicidal power of alpha radiation in sterilizing germinating Bacillus anthracis spores

scientific article

Nanoconjugation of PSMA-Targeting Ligands Enhances Perinuclear Localization and Improves Efficacy of Delivered Alpha-Particle Emitters against Tumor Endothelial Analogues

scientific article

Pharmacokinetics, microscale distribution, and dosimetry of alpha-emitter-labeled anti-PD-L1 antibodies in an immune competent transgenic breast cancer model

scientific article published on 18 July 2017

Preclinical Targeted α- and β--Radionuclide Therapy in HER2-Positive Brain Metastasis Using Camelid Single-Domain Antibodies

scientific article published on 21 April 2020

Preventing Radiobleaching of Cyanine Fluorophores Enhances Stability of Nuclear/NIRF Multimodality Imaging Agents

scientific article published on January 2017

Production of 230U/226Th for targeted alpha therapy via proton irradiation of 231Pa.

scientific article published on 17 October 2008

Prolonged survival in secondary glioblastoma following local injection of targeted alpha therapy with 213Bi-substance P analogue.

scientific article published on 30 April 2018

Radiofungicidal effects of external gamma radiation and antibody-targeted beta and alpha radiation on Cryptococcus neoformans

scientific article published on 31 March 2008

Radioimmunotherapy is more effective than antifungal treatment in experimental cryptococcal infection

scientific article

Radioimmunotherapy of Cryptococcus neoformans spares bystander mammalian cells

scientific article published on September 2013

Radiolabeled antibodies to Bacillus anthracis toxins are bactericidal and partially therapeutic in experimental murine anthrax

scientific article published on 24 August 2009

Safety and efficacy of targeted alpha therapy with 213Bi-DOTA-substance P in recurrent glioblastoma

scientific article published on 29 November 2018

Single-Dose Anti-CD138 Radioimmunotherapy: Bismuth-213 is More Efficient than Lutetium-177 for Treatment of Multiple Myeloma in a Preclinical Model

scientific article

Spectroscopic study of the interaction of U(VI) with transferrin and albumin for speciation of U(VI) under blood serum conditions

scientific article

Targeted alpha therapy with 213Bi

scientific article published on October 2011

Targeted α-Therapy of Metastatic Castration-Resistant Prostate Cancer with 225Ac-PSMA-617: Dosimetry Estimate and Empiric Dose Finding

scientific article published on 13 April 2017

Targeting aberrant DNA double-strand break repair in triple-negative breast cancer with alpha-particle emitter radiolabeled anti-EGFR antibody

scientific article published on 19 July 2013

The Road to Personalized Myeloma Medicine: Patient-specific Single-domain Antibodies for Anti-idiotypic Radionuclide Therapy

scientific article published in January 2022

Therapeutic Efficacy of Alpha-RIT Using a (213)Bi-Anti-hCD138 Antibody in a Mouse Model of Ovarian Peritoneal Carcinomatosis

scientific article

Therapeutic efficacy and toxicity of 225Ac-labelled vs. 213Bi-labelled tumour-homing peptides in a preclinical mouse model of peritoneal carcinomatosis

scientific article published on 12 January 2012

Therapeutic efficacy of α-radioimmunotherapy with different activity levels of the 213Bi-labeled monoclonal antibody MX35 in an ovarian cancer model

scientific article

Treatment of carcinoma in situ of the urinary bladder with an alpha-emitter immunoconjugate targeting the epidermal growth factor receptor: a pilot study.

scientific article published on 11 April 2018

Treatment of early and established Cryptococcus neoformans infection with radiolabeled antibodies in immunocompetent mice

scientific article published on 17 October 2011

Treatment of experimental pancreatic cancer with 213-Bismuth-labeled chimeric antibody to single-strand DNA.

scientific article published on 26 August 2014

Treatment of peritoneal carcinomatosis by targeted delivery of the radio-labeled tumor homing peptide bi-DTPA-[F3]2 into the nucleus of tumor cells

scientific article

Unprecedented incorporation of α-emitter radioisotope 213Bi into porphyrin chelates with reference to a daughter isotope mediated assistance mechanism

scientific article published on 27 June 2011

²¹³Bi-anti-EGFR radioimmunoconjugates and X-ray irradiation trigger different cell death pathways in squamous cell carcinoma cells

scientific article published on 9 October 2013

α- Versus β-Emitting Radionuclides for Pretargeted Radioimmunotherapy of Carcinoembryonic Antigen-Expressing Human Colon Cancer Xenografts

scientific article published on 23 February 2017

α-Radioimmunotherapy with ²¹³Bi-anti-CD38 immunoconjugates is effective in a mouse model of human multiple myeloma

scientific article

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