Search filters

List of works by Irene Knuesel

A role for synGAP in regulating neuronal apoptosis

scientific journal article

Abnormal differentiation of newborn granule cells in age-related working memory impairments

scientific article published on 18 December 2008

Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging

scientific article published on 4 September 2009

Adult brain and behavioral pathological markers of prenatal immune challenge during early/middle and late fetal development in mice.

scientific article

Age-related accumulation of Reelin in amyloid-like deposits

scientific article published on 27 September 2007

An In Vitro Bone Model to Investigate the Role of Triggering Receptor Expressed on Myeloid Cells-2 in Bone Homeostasis

scientific article published on 01 July 2018

Appetitively motivated instrumental learning in SynGAP heterozygous knockout mice

scientific article published in October 2009

Characterization and turnover of CD73/IP(3)R3-positive microvillar cells in the adult mouse olfactory epithelium

scientific article

Chronic clozapine treatment improves prenatal infection-induced working memory deficits without influencing adult hippocampal neurogenesis

scientific article published on 30 December 2009

Co-localization of Reelin and proteolytic AbetaPP fragments in hippocampal plaques in aged wild-type mice

scientific article published in January 2010

Contrast-Enhanced Magnetic Resonance Microangiography Reveals Remodeling of the Cerebral Microvasculature in Transgenic ArcAβ Mice ⬇️

scientific article published on February 1, 2012

Contribution of early Alzheimer's disease-related pathophysiology to the development of acquired epilepsy

scientific article published on 19 June 2018

Deciphering the mechanism underlying late-onset Alzheimer disease ⬇️

scientific article published on November 27, 2012

Detection of cerebral microbleeds with quantitative susceptibility mapping in the ArcAbeta mouse model of cerebral amyloidosis

scientific article published on 17 August 2011

Differential expression of PSD proteins in age-related spatial learning impairments

scientific article published on 28 December 2005

Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a procognitive and antipsychotic phenotypic profile.

scientific article

Disruption of hippocampus-regulated behavioural and cognitive processes by heterozygous constitutive deletion of SynGAP.

scientific article published on 25 January 2010

Evolution of a maternal immune activation (mIA) model in rats: Early developmental effects

scientific article published on 12 September 2018

Extrusion of misfolded and aggregated proteins – a protective strategy of aging neurons? ⬇️

scientific article published on June 1, 2012

GABAergic terminals are required for postsynaptic clustering of dystrophin but not of GABA(A) receptors and gephyrin.

scientific article

Hippocampal pyramidal cells: the reemergence of cortical lamination ⬇️

scientific article published on May 20, 2011

Impact of Prenatal Immune System Disturbances on Brain Development ⬇️

scientific article published on May 13, 2012

Impaired reelin processing and secretion by Cajal-Retzius cells contributes to granule cell dispersion in a mouse model of temporal lobe epilepsy

scientific article published on 17 May 2010

Increased vulnerability to kainate-induced seizures in utrophin-knockout mice

scientific article published in May 2002

Long-term effects of early life deprivation on brain glia in Fischer rats.

scientific article published on 18 January 2007

Longitudinal Assessment of Amyloid Pathology in Transgenic ArcAβ Mice Using Multi-Parametric Magnetic Resonance Imaging

scientific article

Maternal immune activation and abnormal brain development across CNS disorders.

scientific article

Molecular and behavioral changes associated with adult hippocampus-specific SynGAP1 knockout ⬇️

scientific article published on June 14, 2012

NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS

scientific article published on 06 June 2018

Novel role of cystic fibrosis transmembrane conductance regulator in maintaining adult mouse olfactory neuronal homeostasis

scientific article published on 15 October 2014

Postnatal ontogeny of hippocampal expression of the mineralocorticoid and glucocorticoid receptors in the common marmoset monkey

scientific article published in March 2005

Primate early life stress leads to long-term mild hippocampal decreases in corticosteroid receptor expression.

scientific article published on 4 February 2010

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

scientific article published on July 2010

Reelin immunoreactivity in neuritic varicosities in the human hippocampal formation of non-demented subjects and Alzheimer's disease patients.

scientific article published on 26 June 2013

Reelin-mediated Signaling during Normal and Pathological Forms of Aging ⬇️

scientific article published on June 4, 2010

Reelin-mediated signaling in neuropsychiatric and neurodegenerative diseases

scientific article

Regulated Proteolytic Processing of Reelin through Interplay of Tissue Plasminogen Activator (tPA), ADAMTS-4, ADAMTS-5, and Their Modulators ⬇️

scientific article published on October 17, 2012

Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge

scientific article published on 18 April 2007

Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors

scientific article published on 05 December 2019

SynGAP regulates spine formation

scientific article

Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice ⬇️

scientific article published on July 2, 2012

TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance

scientific article

The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.

scientific article published on 30 May 2017

The airbag problem-a potential culprit for bench-to-bedside translational efforts: relevance for Alzheimer's disease

scientific article

The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology.

scientific article published in May 2006

Paulina is supported by:

About Paulina

Help