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List of works by Masatoshi Kitagawa

ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells

scientific article

Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase

scientific article published on 13 August 2009

Analyses in transfected cells and in vitro of a putative peroxisomal targeting signal of rat liver serine:pyruvate aminotransferase

scientific article published on 5 September 2002

Anti-VEGF antibody therapy induces tumor hypoxia and stanniocalcin 2 expression and potentiates growth of human colon cancer xenografts

scientific article published on 6 January 2014

Anti-cancer agent-induced nephrotoxicity

scientific article

Cell cycle regulation by long non-coding RNAs

scientific article published on 24 July 2013

Cell cycle-dependent regulation of the human aurora B promoter

scientific article published in April 2004

Cellular FLIP inhibits beta-catenin ubiquitylation and enhances Wnt signaling.

scientific article published on October 2004

Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling ⬇️

scientific article published on April 13, 2012

Cks1 is degraded via the ubiquitin‐proteasome pathway in a cell cycle‐dependent manner ⬇️

scientific article published on November 1, 2003

Contribution of extracellular signal-regulated kinases to the IL-1-induced growth inhibition of human melanoma cells A375.

scientific article published on 9 November 2007

Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion

scientific article

Decrease in tumor necrosis factor-alpha receptor-associated death domain results from ubiquitin-dependent degradation in obstructive renal injury in rats

scientific article published on 18 June 2009

Degradation of Tob1 mediated by SCFSkp2-dependent ubiquitination

scientific article published on September 2006

Down-regulation of Smad7 expression by ubiquitin-dependent degradation contributes to renal fibrosis in obstructive nephropathy in mice

scholarly article

Dual mode of regulation of cell division cycle 25 A protein by TRB3.

scientific article published on January 2010

E3 Ubiquitin Ligases as Molecular Targets in Human Oral Cancers

scientific article

Effects of MdmX on Mdm2-mediated downregulation of pRB

scientific article

Enhanced Mdm2 activity inhibits pRB function via ubiquitin-dependent degradation

scientific article

Evidence that reactive oxygen species do not mediate NF-kappaB activation

scientific article

Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development

scientific article published on July 2014

Generation of a constitutively active mutant of human GPR48/LGR4, a G-protein-coupled receptor.

scientific article published on March 2006

Hepatocyte Growth Factor stimulated cell scattering requires ERK and Cdc42-dependent tight junction disassembly ⬇️

scientific article published on August 20, 2010

High expression of Pirh2, an E3 ligase for p27, is associated with low expression of p27 and poor prognosis in head and neck cancers

scientific article

Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression

scientific article

Homeobox Transcription Factor NKX2-1 Promotes Cyclin D1 Transcription in Lung Adenocarcinomas

scientific article published on 20 June 2017

Inhibiting Skp2 E3 Ligase Suppresses Bleomycin-Induced Pulmonary Fibrosis

scientific article published on 6 February 2018

Interaction between RB protein and NuMA is required for proper alignment of spindle microtubules

scientific article published on 19 December 2013

Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein

scientific article published on April 2016

Long non-coding RNAs involved in cancer development and cell fate determination

scientific article published on December 2012

Mdm2-mediated pRB downregulation is involved in carcinogenesis in a p53-independent manner

scientific article published on 6 December 2005

Molecular clearance of ataxin-3 is regulated by a mammalian E4

scientific article

Novel insights into FGD3, a putative GEF for Cdc42, that undergoes SCF(FWD1/beta-TrCP)-mediated proteasomal degradation analogous to that of its homologue FGD1 but regulates cell morphology and motility differently from FGD1.

scientific article

Phosphorylated HBO1 at UV irradiated sites is essential for nucleotide excision repair.

scientific article

Phosphorylation of pRB at Ser612 by Chk1/2 leads to a complex between pRB and E2F-1 after DNA damage

scientific article

Pirh2 interacts with and ubiquitylates signal recognition particle receptor beta subunit

scientific journal article

Pirh2 promotes ubiquitin-dependent degradation of the cyclin-dependent kinase inhibitor p27Kip1.

scientific article

RING-, HECT-, and RBR-type E3 Ubiquitin Ligases: Involvement in Human Cancer

scientific article

Regulation of DNA replication licensing

scientific article published on December 2012

Regulation of GATA-binding protein 2 levels via ubiquitin-dependent degradation by Fbw7: involvement of cyclin B-cyclin-dependent kinase 1-mediated phosphorylation of THR176 in GATA-binding protein 2.

scientific article published on 10 February 2015

Renal damage in obstructive nephropathy is decreased in Skp2-deficient mice

scientific article

Role of the second-largest subunit of DNA polymerase alpha in the interaction between the catalytic subunit and hyperphosphorylated retinoblastoma protein in late S phase

scientific article

Roles of the Skp2/p27 axis in the progression of chronic nephropathy

scientific article published on 20 December 2012

SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.

scientific article published on 12 February 2016

The SCF ubiquitin ligases involved in hematopoietic lineage

scientific article published on December 2012

The SCF-type E3 Ubiquitin Ligases as Cancer Targets

scientific article

The amelioration of renal damage in Skp2-deficient mice canceled by p27 Kip1 deficiency in Skp2-/- p27-/- mice ⬇️

scientific article published on April 27, 2012

The role of Sp1 and AP-2 in basal and protein kinase A--induced expression of mitochondrial serine:pyruvate aminotransferase in hepatocytes

scientific article

Transcriptional induction of Smurf2 ubiquitin ligase by TGF-beta

scientific article (publication date: 9 May 2005)

Treatment with anti-TGF-beta antibody ameliorates chronic progressive nephritis by inhibiting Smad/TGF-beta signaling

scientific article published in January 2004

UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation

scientific article published on 16 November 2015

Ubiquitin-dependent degradation of adenovirus E1A protein is inhibited by BS69.

scientific article

Ubiquitin-mediated control of oncogene and tumor suppressor gene products

scientific article published on 19 May 2009

Up-regulation of Cks1 and Skp2 with TNFα/NF-κB signaling in chronic progressive nephropathy ⬇️

scientific article published on November 1, 2011

Up-regulation of GPR48 induced by down-regulation of p27Kip1 enhances carcinoma cell invasiveness and metastasis

scientific article

YB-1 promotes transcription of cyclin D1 in human non-small-cell lung cancers

scientific article published on 29 April 2014

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