List of works - Heiner Westphal

A role of the LIM-homeobox gene Lhx2 in the regulation of pituitary development

scientific article

Azoospermia in patients heterozygous for a mutation in SYCP3

scientific article

Cloning and characterization of the 5'-flanking region of the Ehox gene

scientific article published on 9 January 2006

Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10−/− Mice ⬇️

scientific article published on May 15, 2011

Dkk1 and Dkk2 regulate epicardial specification during mouse heart development

scientific article

Dkk1 and Wnt3 interact to control head morphogenesis in the mouse

scientific article

Dkk1 and noggin cooperate in mammalian head induction

scientific article

Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium

scientific article

Effects of cerebral ischemia in mice deficient in Persephin

scientific article

FoxP4, a novel forkhead transcription factor

scientific article (publication date: 19 June 2003)

Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes

scientific journal article

Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation

scientific journal article

Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice

scientific journal article

Generation and characterization of dickkopf3 mutant mice

scientific article

Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse

scientific journal article

H3K9 histone acetylation predicts pluripotency and reprogramming capacity of ES cells.

scientific article published on July 2011

Homeobox genes and human genetic disorders

scientific article

Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter

scientific journal article

Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase-beta

scientific article published on 22 February 2007

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

scientific journal article

Isl1 and Ldb Co‐regulators of transcription are essential early determinants of mouse limb development ⬇️

scientific article published on April 1, 2012

Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.

scientific article published on 27 November 2012

LIM-homeobox gene Lhx5 is required for normal development of Cajal-Retzius cells

scientific article

LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum

scientific journal article

Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord

scientific journal article

Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors.

scientific article

Mbx, a novel mouse homeobox gene

scientific article (publication date: March 2002)

Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive

scientific article (publication date: 15 December 2002)

Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes

scientific article published on 21 March 2016

Molecular cloning and expression analysis of MPP alpha-2, a novel mouse transcript detected in a differential screen of pituitary libraries

scientific article

Nitric oxide negatively regulates mammalian adult neurogenesis

scientific article

Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8

scientific journal article

Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice

scientific article (publication date: March 2004)

Restoring stemness

scientific article

Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system

scientific journal article

Role of ldb1 in adult intestinal homeostasis

scientific article published on 30 October 2009

Sfrp5 is not essential for axis formation in the mouse

scientific article published on 01 December 2006

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice

scientific article

Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development

scientific article

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex

scientific journal article

Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

scientific article

Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density

scientific journal article

The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain

scientific article

The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration

scientific journal article

The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice

scientific journal article

Transcriptional Regulation by CHIP/LDB Complexes ⬇️

scientific article published on August 12, 2010

List of works by Heiner Westphal

A role of the LIM-homeobox gene Lhx2 in the regulation of pituitary development

Azoospermia in patients heterozygous for a mutation in SYCP3

Cloning and characterization of the 5'-flanking region of the Ehox gene

Contribution of Abcc10 (Mrp7) to In Vivo Paclitaxel Resistance as Assessed in Abcc10−/− Mice ⬇️

Dkk1 and Dkk2 regulate epicardial specification during mouse heart development

Dkk1 and Wnt3 interact to control head morphogenesis in the mouse

Dkk1 and noggin cooperate in mammalian head induction

Dkk2 plays an essential role in the corneal fate of the ocular surface epithelium

Effects of cerebral ischemia in mice deficient in Persephin

FoxP4, a novel forkhead transcription factor

Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes

Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation

Gdnf haploinsufficiency causes Hirschsprung-like intestinal obstruction and early-onset lethality in mice

Generation and characterization of dickkopf3 mutant mice

Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse

H3K9 histone acetylation predicts pluripotency and reprogramming capacity of ES cells.

Homeobox genes and human genetic disorders

Impaired glucose homeostasis, neutrophil trafficking and function in mice lacking the glucose-6-phosphate transporter

Impaired neutrophil activity and increased susceptibility to bacterial infection in mice lacking glucose-6-phosphatase-beta

Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

Isl1 and Ldb Co‐regulators of transcription are essential early determinants of mouse limb development ⬇️

Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.

LIM-homeobox gene Lhx5 is required for normal development of Cajal-Retzius cells

LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum

Lhx1 and Lhx5 maintain the inhibitory-neurotransmitter status of interneurons in the dorsal spinal cord

Lhx6 and Lhx8 coordinately induce neuronal expression of Shh that controls the generation of interneuron progenitors.

Mbx, a novel mouse homeobox gene

Mice lacking D5 dopamine receptors have increased sympathetic tone and are hypertensive

Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes

Molecular cloning and expression analysis of MPP alpha-2, a novel mouse transcript detected in a differential screen of pituitary libraries

Nitric oxide negatively regulates mammalian adult neurogenesis

Oogenesis requires germ cell-specific transcriptional regulators Sohlh1 and Lhx8

Profound impairment in social recognition and reduction in anxiety-like behavior in vasopressin V1a receptor knockout mice

Restoring stemness

Rho family Guanine nucleotide exchange factor Brx couples extracellular signals to the glucocorticoid signaling system

Role of ldb1 in adult intestinal homeostasis

Sfrp5 is not essential for axis formation in the mouse

Simultaneous absence of dopamine D1 and D2 receptor-mediated signaling is lethal in mice

Ssdp proteins interact with the LIM-domain-binding protein Ldb1 to regulate development

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex

Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo

Targeted disruption of the Wnt regulator Kremen induces limb defects and high bone density

The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain

The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration

The Rho guanine nucleotide exchange factor AKAP13 (BRX) is essential for cardiac development in mice

Transcriptional Regulation by CHIP/LDB Complexes ⬇️