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List of works by Eero I Vuorio

A metaphyseal defect model of the femur for studies of murine bone healing

scientific article

Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene

scientific article published in November 2004

Abnormal craniofacial growth and early mandibular osteoarthritis in mice harbouring a mutant type II collagen transgene

scientific journal article

Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene

scientific article published on 01 July 1993

Abnormalities in secondary cartilages in four lines of transgenic mice harboring two different types of mutations in the cartilage-specific type II collagen gene

scientific article published on 01 July 1996

Accelerated up-regulation of L-Sox5, Sox6, and Sox9 by BMP-2 gene transfer during murine fracture healing

scientific article (publication date: October 2001)

Activation of chondrogenesis in response to injury in normal and transgenic mice with cartilage collagen mutations

scientific article published on January 1, 2001

Adenovirus mediated intra-articular expression of collagenase-3 (MMP-13) induces inflammatory arthritis in mice

scientific article published on June 2004

Age-dependent changes in the expression of matrix components in the mouse eye

scientific journal article

Altered expression of genes involved in the production and degradation of endometrial extracellular matrix in patients with unexplained infertility and recurrent miscarriages

scientific article published on 01 December 2002

Analysis of aggrecan and tenascin gene expression in mouse skeletal tissues by northern and in situ hybridization using species specific cDNA probes

scientific article

Analysis of arthritic lesions in the Del1 mouse: a model for osteoarthritis

scientific article published on 01 January 2007

Antisense RNA inhibition of cathepsin L expression reduces tumorigenicity of malignant cells

scientific article

Assembly of cartilage collagen fibrils is disrupted by overexpression of normal type II collagen in transgenic mice

scientific article

Cathepsin K deficiency aggravates lung injury in hyperoxia-exposed newborn mice ⬇️

scientific article published on 01 July 2011

Cathepsin expression during skeletal development

scientific article (publication date: 7 July 1999)

Characterization of primary cultures of chondrocytes from type II collagen/beta-galactosidase transgenic mice

scientific article published on 01 August 1994

Characterization of the murine Timp4 gene, localization within intron 5 of the synapsin 2 gene and tissue distribution of the mRNA.

scientific article

Chondrodysplasia in transgenic mice harboring a 15-amino acid deletion in the triple helical domain of pro alpha 1(II) collagen chain

scientific article published on July 1992

Collagens and collagen-related matrix components in the human and mouse eye.

scientific article published in July 2004

Conservation of the sizes of 53 introns and over 100 intronic sequences for the binding of common transcription factors in the human and mouse genes for type II procollagen (COL2A1).

scientific article published on June 1995

Coordinate patterns of expression of type I and III collagens during mouse development

scientific article published in December 1995

Cysteine proteinases in chondrosarcomas

scientific article

Developmental expression of a type II collagen/beta-galactosidase fusion gene in transgenic mice

scientific article published in October 1995

Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis

scientific article

Differential turnover of cortical and trabecular bone in transgenic mice overexpressing cathepsin K.

scientific article

Effect of radiosynovectomy with holmium-166 ferric hydroxide macroaggregate on adult equine cartilage.

scientific article published on February 2004

Effect of zoledronic acid on incorporation of a bioceramic bone graft substitute

scientific article

Evidence for insufficient chondrocytic differentiation during repair of full-thickness defects of articular cartilage

scientific article published on April 1996

Exclusion of the COL2A1 gene as the mutation site in diastrophic dysplasia.

scientific article

Expression of cathepsins B, H, K, L, and S and matrix metalloproteinases 9 and 13 during chondrocyte hypertrophy and endochondral ossification in mouse fracture callus

scientific article (publication date: November 2000)

Expression of type II and IX collagen isoforms during normal and pathological cartilage and eye development ⬇️

scientific article published on 01 August 1998

Expression of type VI, IX and XI collagen genes and alternative splicing of type II collagen transcripts in fracture callus tissue in mice

scientific article published on 01 May 1995

Expression patterns of cartilage collagens and Sox9 during mouse heart development

scientific article published on 18 July 2003

Expression patterns of cathepsins B, H, K, L and S in the human endometrium

scientific article (publication date: 2001)

Generation and use of transgenic mice as models of osteoarthritis

scientific article published on 01 January 2004

Growth retardation in transgenic mice harboring a type II collagen mutation

scientific article published on 01 June 1996

Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio

scientific article published on 24 November 2004

Incorporation of cortical bone allografts and autografts in rats: expression patterns of mRNAs for the TGF-betas

scientific article published on 01 October 1998

Individual Timp deficiencies differentially impact pro-MMP-2 activation

scientific article published on 9 February 2006

Lifelong voluntary joint loading increases osteoarthritis in mice housing a deletion mutation in type II procollagen gene, and slightly also in non-transgenic mice

scientific article published on September 2002

Localization of osteonectin expression in human fetal skeletal tissues by in situ hybridization

scientific article (publication date: September 1989)

Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene.

scientific article published in April 1997

Mice with a deletion in the first intron of the Col1a1 gene develop age-dependent aortic dissection and rupture

scientific journal article

Mice with tissue inhibitor of metalloproteinases 4 (Timp4) deletion succumb to induced myocardial infarction but not to cardiac pressure overload.

scientific article published on June 2010

Molecular biological evaluation of bioactive glass microspheres and adjunct bone morphogenetic protein 2 gene transfer in the enhancement of new bone formation

scientific article published in March 2005

Molecular cloning of the human alpha 2(IX) collagen cDNA and assignment of the human COL9A2 gene to chromosome 1

scientific article

Molecular profiling of human chondrosarcomas for matrix production and cancer markers

scientific article published on 01 July 2002

Molecular profiling of polycystic ovaries for markers of cell invasion and matrix turnover.

scientific article published in April 2005

Mouse type II collagen gene. Complete nucleotide sequence, exon structure, and alternative splicing

scientific article

Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice

scientific article published on December 1, 1997

No improvement in the overall survival of 194 patients with chondrosarcoma in Finland in 1971-1990

scientific article published on 01 June 2003

Normal long bone growth and development in type X collagen-null mice

scientific article published on 01 October 1994

Ocular abnormalities in transgenic mice harboring mutations in the type II collagen gene

scientific article published on 01 October 1996

Osteoarthritis-like lesions in transgenic mice harboring a small deletion mutation in type II collagen gene

scientific article published on 01 July 2000

Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation

scientific article published on 16 January 2013

Overexpression of cathepsin K accelerates the resorption cycle and osteoblast differentiation in vitro

scientific article

Prepublication data sharing

scientific article

Purification and molecular cloning of the "A" chain of a rat heteromeric CCAAT-binding protein. Sequence identity with the yeast HAP3 transcription factor

scientific journal article

Reduced amounts of cartilage collagen fibrils and growth plate anomalies in transgenic mice harboring a glycine-to-cysteine mutation in the mouse type II procollagen alpha 1-chain gene

scientific article

Retarded chondrogenesis in transgenic mice with a type II collagen defect results in fracture healing abnormalities

scientific article published on 01 August 1994

Roadmap for a precision-medicine initiative in the Nordic region

scientific article published on 01 June 2019

Sequence analysis of regulatory regions of the human collagen X gene

article

Specific hybridization probes for mouse alpha 2(IX) and alpha 1(X) collagen mRNAs.

scientific article published in February 1992

Specific hybridization probes for mouse type I, II, III and IX collagen mRNAs

scientific article published in June 1991

Spontaneous development of synovitis and cartilage degeneration in transgenic mice overexpressing cathepsin K

scientific article published on 01 December 2005

Structural analysis of the regulatory elements of the type-II procollagen gene. Conservation of promoter and first intron sequences between human and mouse

scientific article published on July 1992

Temporospatial expression of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in mouse antigen-induced arthritis

scientific article published on 27 August 2005

The B subunit of a rat heteromeric CCAAT-binding transcription factor shows a striking sequence identity with the yeast Hap2 transcription factor

scientific article

The exon structure of the mouse alpha 2(IX) collagen gene shows unexpected divergence from the chick gene

scientific article published on February 1994

The genes encoding alpha 2(IX) collagen (COL9A2) map to human chromosome 1p32.3-p33 and mouse chromosome 4

scientific article

The mouse collagen X gene: complete nucleotide sequence, exon structure and expression pattern

scientific article published on January 1993

Tissue inhibitor of metalloproteinases 4 (TIMP4) is involved in inflammatory processes of human cardiovascular pathology

scientific article

Transcriptional control mechanisms for the expression of type I collagen genes ⬇️

scientific article published on November 1, 1991

Transgenic Mice as Models for Heritable Diseases ⬇️

scientific article published on April 1, 1992

Transgenic mice with deficiencies in cartilage collagens: possible models for gene therapy.

scientific article published on February 1995

Tutkimusetiikka Suomessa 1980-luvulta tähän päivään ⬇️

journal article from 'Tieteessä tapahtuu' published in 2013

Ultrastructural characterization of developmental and degenerative vitreo-retinal changes in the eyes of transgenic mice with a deletion mutation in type II collagen gene

scientific article published in June 2002

Variability in the upstream promoter and intron sequences of the human, mouse and chick type X collagen genes

scientific article

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