List of works - Erik A L Biessen

Ablation of CD8α(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

scientific article

Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13.

scientific article published on 31 March 2014

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

scientific article

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice

scientific article published on 12 September 2014

Assessment of unstable atherosclerosis in mice

scientific article published on March 2007

Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation

scientific article

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

scientific article published on 03 February 2014

Blocking endothelial adhesion molecules: a potential therapeutic strategy to combat atherogenesis

scientific article published in October 2004

CCL3 (MIP-1 alpha) levels are elevated during acute coronary syndromes and show strong prognostic power for future ischemic events

scientific article

CXCR4 blockade induces atherosclerosis by affecting neutrophil function

scientific article published on 8 May 2014

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice

scientific article

Caveolin‐1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T‐cell response ⬇️

scientific article published on July 27, 2011

Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes

scientific article

Control of atherosclerotic plaque vulnerability: insights from transgenic mice

scientific article published on May 2008

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

scientific article

Design and Validation of a Specific Scavenger Receptor Class AI Binding Peptide for Targeting the Inflammatory Atherosclerotic Plaque ⬇️

scientific article published on January 26, 2012

Efficient degradation-aided selection of protease inhibitors by phage display.

scientific article

Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

scientific article

Feasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-β

scientific article

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner

scientific article (publication date: 2013)

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility

scientific article

Hematopoietic G‐protein‐coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor‐knockout mice ⬇️

scientific article published on October 9, 2012

Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice

scientific article

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

scientific article

High-sensitive troponin T assay for the diagnosis of acute myocardial infarction: an economic evaluation

scientific article

IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype ⬇️

scientific article published on February 1, 2011

Identification of a novel CD40 ligand for targeted imaging of inflammatory plaques by phage display

scientific article

Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis – Potential role in plaque stabilization

Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms

scientific article published on 16 November 2004

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

scientific article

Leukocyte cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses

scientific article

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

scientific article

Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model

scientific article published on October 2012

Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice

scientific article published on 22 June 2016

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

scientific article published on 29 January 2018

P-selectin as a candidate target in atherosclerosis

scientific article

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet

scientific article

Plaque-associated vasa vasorum in aged apolipoprotein E-deficient mice exhibit proatherogenic functional features in vivo

scientific article

Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity

scientific article published on 20 October 2011

Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis

scientific article published on 8 November 2007

Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression

scientific article

Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype

scientific article published on 20 August 2013

Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists

scientific article

SDF-1α/CXCR4 Axis Is Instrumental in Neointimal Hyperplasia and Recruitment of Smooth Muscle Progenitor Cells

article by Alma Zernecke et al published 15 April 2005 in Circulation Research

Scavenger receptor-AI-targeted iron oxide nanoparticles for in vivo MRI detection of atherosclerotic lesions

scientific article published on 6 June 2013

Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists

scientific article

Targeting of peptides to restenotic vascular smooth muscle cells using phage display in vitro and in vivo

scientific article published in August 2002

The effect of TGF-beta receptor binding peptides on smooth muscle cells

scientific article

The peripheral blood mononuclear cell microRNA signature of coronary artery disease

scientific article

Therapeutic potential of VIVIT, a selective peptide inhibitor of nuclear factor of activated T cells, in cardiovascular disorders

scientific article published on January 2007

Uptake and processing of modified bacteriophage M13 in mice: implications for phage display

scientific article

Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro

scientific article

Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression.

scientific article published on 15 September 2017

Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice

scientific article

List of works by Erik A L Biessen

Ablation of CD8α(+) dendritic cell mediated cross-presentation does not impact atherosclerosis in hyperlipidemic mice

Activated platelets promote increased monocyte expression of CXCR5 through prostaglandin E2-related mechanisms and enhance the anti-inflammatory effects of CXCL13.

Angiopoietin-2 blocking antibodies reduce early atherosclerotic plaque development in mice

AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice

Assessment of unstable atherosclerosis in mice

Atherosclerotic lesion progression changes lysophosphatidic acid homeostasis to favor its accumulation

Blocking CD40-TRAF6 signaling is a therapeutic target in obesity-associated insulin resistance

Blocking endothelial adhesion molecules: a potential therapeutic strategy to combat atherogenesis

CCL3 (MIP-1 alpha) levels are elevated during acute coronary syndromes and show strong prognostic power for future ischemic events

CXCR4 blockade induces atherosclerosis by affecting neutrophil function

Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice

Caveolin‐1 deficiency decreases atherosclerosis by hampering leukocyte influx into the arterial wall and generating a regulatory T‐cell response ⬇️

Chemokines CCL3/MIP1α, CCL5/RANTES and CCL18/PARC are independent risk predictors of short-term mortality in patients with acute coronary syndromes

Control of atherosclerotic plaque vulnerability: insights from transgenic mice

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

Design and Validation of a Specific Scavenger Receptor Class AI Binding Peptide for Targeting the Inflammatory Atherosclerotic Plaque ⬇️

Efficient degradation-aided selection of protease inhibitors by phage display.

Endothelial KLF2 links local arterial shear stress levels to the expression of vascular tone-regulating genes

Feasibility of in vivo 18F-florbetaben PET/MR imaging of human carotid amyloid-β

Genetic and pharmacological modifications of thrombin formation in apolipoprotein e-deficient mice determine atherosclerosis severity and atherothrombosis onset in a neutrophil-dependent manner

Hck/Fgr Kinase Deficiency Reduces Plaque Growth and Stability by Blunting Monocyte Recruitment and Intraplaque Motility

Hematopoietic G‐protein‐coupled receptor kinase 2 deficiency decreases atherosclerotic lesion formation in LDL receptor‐knockout mice ⬇️

Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice

High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-κB/STAT1-IRF1 Signaling

High-sensitive troponin T assay for the diagnosis of acute myocardial infarction: an economic evaluation

IGF-1 Has Plaque-Stabilizing Effects in Atherosclerosis by Altering Vascular Smooth Muscle Cell Phenotype ⬇️

Identification of a novel CD40 ligand for targeted imaging of inflammatory plaques by phage display

Increased levels of the homeostatic chemokine CXCL13 in human atherosclerosis – Potential role in plaque stabilization

Interleukin-10 enhances the oxidized LDL-induced foam cell formation of macrophages by antiapoptotic mechanisms

Interleukins in atherosclerosis: molecular pathways and therapeutic potential

Leukocyte cathepsin C deficiency attenuates atherosclerotic lesion progression by selective tuning of innate and adaptive immune responses

MicroRNA profiling identifies microRNA-155 as an adverse mediator of cardiac injury and dysfunction during acute viral myocarditis

Myocardial regeneration by transplantation of modified endothelial progenitor cells expressing SDF-1 in a rat model

Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice

Noncanonical NF-κB signaling in microvessels of atherosclerotic lesions is associated with inflammation, atheromatous plaque morphology and myocardial infarction

P-selectin as a candidate target in atherosclerosis

Pharmacological Treatment with Annexin A1 Reduces Atherosclerotic Plaque Burden in LDLR-/- Mice on Western Type Diet

Plaque-associated vasa vasorum in aged apolipoprotein E-deficient mice exhibit proatherogenic functional features in vivo

Plasmacytoid dendritic cells protect against atherosclerosis by tuning T-cell proliferation and activity

Protective role of CXC receptor 4/CXC ligand 12 unveils the importance of neutrophils in atherosclerosis

Quaking promotes monocyte differentiation into pro-atherogenic macrophages by controlling pre-mRNA splicing and gene expression

Quaking, an RNA-binding protein, is a critical regulator of vascular smooth muscle cell phenotype

Rational optimization of a short human P-selectin-binding peptide leads to nanomolar affinity antagonists

SDF-1α/CXCR4 Axis Is Instrumental in Neointimal Hyperplasia and Recruitment of Smooth Muscle Progenitor Cells

Scavenger receptor-AI-targeted iron oxide nanoparticles for in vivo MRI detection of atherosclerotic lesions

Specific inhibition of P-selectin-mediated cell adhesion by phage display-derived peptide antagonists

Targeting of peptides to restenotic vascular smooth muscle cells using phage display in vitro and in vivo

The effect of TGF-beta receptor binding peptides on smooth muscle cells

The peripheral blood mononuclear cell microRNA signature of coronary artery disease

Therapeutic potential of VIVIT, a selective peptide inhibitor of nuclear factor of activated T cells, in cardiovascular disorders

Uptake and processing of modified bacteriophage M13 in mice: implications for phage display

Viral cross-class serpin inhibits vascular inflammation and T lymphocyte fratricide; a study in rodent models in vivo and human cell lines in vitro

Whole body and hematopoietic ADAM8 deficiency does not influence advanced atherosclerotic lesion development, despite its association with human plaque progression.

Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice