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List of works by Cornelus C Hermsen

A sporozoite-based vaccination platform against human malaria

scientific article published on 24 August 2018

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate--Tackling the Cocktail Challenge

scientific article published on 6 July 2015

Anti-CD81 but not anti-SR-BI blocks Plasmodium falciparum liver infection in a humanized mouse model

scientific article published on 4 February 2015

Antibodies against PfEMP1, RIFIN, MSP3 and GLURP are acquired during controlled Plasmodium falciparum malaria infections in naïve volunteers

scientific article

Antibody Biomarkers Associated with Sterile Protection Induced by Controlled Human Malaria Infection under Chloroquine Prophylaxis

scientific article published on 20 February 2019

Assessing the adequacy of attenuation of genetically modified malaria parasite vaccine candidates

scientific article published on 16 February 2012

Assessment of Parasite Liver-Stage Burden in Human-Liver Chimeric Mice

scientific article published on January 2015

BAFF and BAFF receptor levels correlate with B cell subset activation and redistribution in controlled human malaria infection

scientific article

Bacterium-like particles as multi-epitope delivery platform for Plasmodium berghei circumsporozoite protein induce complete protection against malaria in mice ⬇️

scientific article published on February 20, 2012

Breadth of humoral response and antigenic targets of sporozoite-inhibitory antibodies associated with sterile protection induced by controlled human malaria infection

scientific article

Changes in total and differential leukocyte counts during the clinically silent liver phase in a controlled human malaria infection in malaria-naïve Dutch volunteers

scientific article published on 10 November 2017

Comparison of clinical and parasitological data from controlled human malaria infection trials

scientific article (publication date: 2012)

Controlled human malaria infection of Tanzanians by intradermal injection of aseptic, purified, cryopreserved Plasmodium falciparum sporozoites

scientific article

Controlled human malaria infections by intradermal injection of cryopreserved Plasmodium falciparum sporozoites

scientific article published on 13 November 2012

Cytotoxic markers associate with protection against malaria in human volunteers immunized with Plasmodium falciparum sporozoites

scientific article

DNA prime/Adenovirus boost malaria vaccine encoding P. falciparum CSP and AMA1 induces sterile protection associated with cell-mediated immunity

scientific article

Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

scientific article published on 05 August 2016

Erratum to: Diagnosis and treatment based on quantitative PCR after controlled human malaria infection

scientific article published on 28 October 2016

Evaluation of immunity against malaria using luciferase-expressing Plasmodium berghei parasites ⬇️

scientific article published on December 9, 2011

Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans

scientific article

Extended malaria parasite clearance time in African children following artemisinin-combination therapy enhances transmission to Anopheles mosquitoes

article

External quality assurance of malaria nucleic acid testing for clinical trials and eradication surveillance

scientific article (publication date: 2014)

Filter paper collection of Plasmodium falciparum mRNA for detecting low-density gametocytes

scientific article published on 8 August 2012

Heterologous Protection against Malaria after Immunization with Plasmodium falciparum Sporozoites

scientific article published on May 2015

Identification of a major rif transcript common to gametocytes and sporozoites of Plasmodium falciparum

scientific article

Impact of malaria preexposure on antiparasite cellular and humoral immune responses after controlled human malaria infection

scientific article

Improving statistical inference on pathogen densities estimated by quantitative molecular methods: malaria gametocytaemia as a case study

scientific article

Infectivity of Plasmodium falciparum sporozoites determines emerging parasitemia in infected volunteers.

scientific article published on June 2017

Long term protection after immunization with P. berghei sporozoites correlates with sustained IFNγ responses of hepatic CD8+ memory T cells

scientific article

Long-term protection against malaria after experimental sporozoite inoculation: an open-label follow-up study

scientific article published on 22 April 2011

Longevity and composition of cellular immune responses following experimental Plasmodium falciparum malaria infection in humans

scientific article published on December 2011

Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: a randomized trial

scientific article published on 6 March 2013

Memory B-cell and antibody responses induced by Plasmodium falciparum sporozoite immunization

scientific article

Memory-like IFN-γ response by NK cells following malaria infection reveals the crucial role of T cells in NK cell activation by P. falciparum

scientific article published in December 2010

Modest heterologous protection after Plasmodium falciparum sporozoite immunization: a double-blind randomized controlled clinical trial

scientific article published on 13 September 2017

Molecular detection and quantification of Plasmodium falciparum-infected human hepatocytes in chimeric immune-deficient mice

scientific article published on 24 November 2013

NF135.C10: a new Plasmodium falciparum clone for controlled human malaria infections

scientific article published on 27 November 2012

Outcomes of controlled human malaria infection after BCG vaccination

scholarly article by Jona Walk et al published 20 February 2019 in Nature Communications

Persistence of full-length caspase-12 and its relation to malaria in West and Central African populations

scientific article

Phase 1/2a study of the malaria vaccine candidate apical membrane antigen-1 (AMA-1) administered in adjuvant system AS01B or AS02A.

scientific article

Plasmodium berghei Δp52&p36 Parasites Develop Independent of a Parasitophorous Vacuole Membrane in Huh-7 Liver Cells ⬇️

scientific article published on December 5, 2012

Plasmodium liver load following parenteral sporozoite administration in rodents

scientific article published on 9 October 2012

Pre-erythrocytic antibody profiles induced by controlled human malaria infections in healthy volunteers under chloroquine prophylaxis

scientific article published on 19 December 2013

Protection against a malaria challenge by sporozoite inoculation

scientific article published on July 2009

Protection against malaria after immunization by chloroquine prophylaxis and sporozoites is mediated by preerythrocytic immunity

scientific article published on 18 April 2013

Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum ⬇️

scientific article published on August 4, 2010

Safety, Immunogenicity, and Protective Efficacy of Intradermal Immunization with Aseptic, Purified, Cryopreserved Plasmodium falciparum Sporozoites in Volunteers Under Chloroquine Prophylaxis: A Randomized Controlled Trial

scientific article published on 28 December 2015

Sporozoite immunization of human volunteers under chemoprophylaxis induces functional antibodies against pre-erythrocytic stages of Plasmodium falciparum

scientific article

Sporozoite immunization of human volunteers under mefloquine prophylaxis is safe, immunogenic and protective: a double-blind randomized controlled clinical trial

scientific article

TLR4 polymorphisms, infectious diseases, and evolutionary pressure during migration of modern humans

scientific article

The Power of Malaria Vaccine Trials Using Controlled Human Malaria Infection

scientific article

Two Plasmodium 6-Cys family-related proteins have distinct and critical roles in liver-stage development

scientific article (publication date: May 2014)

Vaccine-induced monoclonal antibodies targeting circumsporozoite protein prevent Plasmodium falciparum infection

scientific article

Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging

scientific article

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