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List of works by Augustine M K Choi

"Therapeutic" carbon monoxide may be a reality soon

scientific article published on 01 June 2005

A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of β-Catenin

scientific article published on 10 February 2016

A Comparative Analysis of the Respiratory Subscore of the Sequential Organ Failure Assessment Scoring System

scientific article published on 01 November 2021

A Peptide with anti-transglutaminase activity decreases lipopolysaccharide-induced lung inflammation in mice

scientific article published on 01 January 2006

A Phase II Clinical Trial of Low-Dose Inhaled Carbon Monoxide in Idiopathic Pulmonary Fibrosis

scientific article

Acute respiratory distress syndrome without identifiable risk factors: A secondary analysis of the ARDS network trials

scientific article published on 02 June 2018

Age-Dependent Susceptibility to Pulmonary Fibrosis Is Associated with NLRP3 Inflammasome Activation

scientific article published on 2 March 2016

Allele-specific transactivation of matrix metalloproteinase 7 by FOXA2 and correlation with plasma levels in idiopathic pulmonary fibrosis

scientific article published on 20 January 2012

Alterations in nitric oxide and cytokine production with airway inflammation in the absence of IL-10.

scientific article

An integrated clinico-metabolomic model improves prediction of death in sepsis

scientific article published on July 2013

Analyzing autophagy in clinical tissues of lung and vascular diseases

scientific article published in January 2009

Apolipoprotein E and Periostin Are Potential Biomarkers of Nasal Mucosal Inflammation. A Parallel Approach of In Vitro and In Vivo Secretomes

scientific article published on 01 January 2020

Association between acute respiratory disease events and the MUC5B promoter polymorphism in smokers

scientific article published on 13 February 2018

Association of plasma mitochondrial DNA with COPD severity and progression in the SPIROMICS cohort

scientific article published on 26 April 2021

Association of urine mitochondrial DNA with clinical measures of COPD in the SPIROMICS cohort

scientific article published on 13 February 2020

Autophagic flux and oxidative capacity of skeletal muscles during acute starvation

scientific article published on 15 August 2013

Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension

scientific article

Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1.

scientific article published on 12 October 2008

Autophagic proteins: new facets of the oxygen paradox

scientific article published on 3 February 2012

Autophagy and Obesity-Related Lung Disease

scientific article published on 22 February 2016

Autophagy and inflammation in chronic respiratory disease.

scientific article

Autophagy in Human Health and Disease ⬇️

scientific article published on May 9, 2013

Autophagy in Pulmonary Diseases

scientific article

Autophagy in chronic lung disease

scientific article published on 12 March 2020

Autophagy in chronic obstructive pulmonary disease: homeostatic or pathogenic mechanism?

scientific article published on 26 February 2009

Autophagy in lung disease pathogenesis and therapeutics

scientific article

Autophagy in pulmonary diseases

scientific article published on 24 October 2011

Autophagy in the lung

scientific article published on February 2010

Autophagy in vascular disease

scientific article published on February 2010

Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema ⬇️

scientific article published on October 18, 2010

Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome

scientific article (publication date: March 2011)

Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide

scientific article

Autophagy: A Critical Regulator of Cellular Metabolism and Homeostasis ⬇️

scientific article published on May 24, 2013

Autophagy: An Integral Component of the Mammalian Stress Response

scientific article published on September 2013

Autophagy: Friend or Foe in Lung Disease?

scientific article published on March 2016

Autophagy: a core cellular process with emerging links to pulmonary disease

scientific article published on 11 August 2011

Autophagy: a crucial moderator of redox balance, inflammation, and apoptosis in lung disease

scientific article published on 26 September 2013

Autophagy: a potential therapeutic target in lung diseases ⬇️

scientific article published on May 24, 2013

Autophagy: cellular defense to excessive inflammation

scientific article published on 05 September 2011

Bcl-XL disrupts death-inducing signal complex formation in plasma membrane induced by hypoxia/reoxygenation

scientific article published in December 2004

Beclin 1 deficiency is associated with increased hypoxia-induced angiogenesis ⬇️

scientific article published on August 1, 2011

Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13

scientific article

Bik reduces hyperplastic cells by increasing Bak and activating DAPk1 to juxtapose ER and mitochondria

scientific article published on 6 October 2017

Biobanking and cryopreservation of human lung explants for omic analysis

scientific article published on 23 January 2020

Brief inhalation of low-dose carbon monoxide protects rodents and swine from postoperative ileus

scientific article published in June 2005

Bronchoprovocation testing in asthma: effect on exhaled monoxides

scientific article published on November 30, 2010

CCAAT/enhancer-binding protein mediates carbon monoxide-induced suppression of cyclooxygenase-2.

scientific article published on 16 March 2006

CD44v3-positive Intermediate Progenitor Cells Contribute to Airway Goblet Cell Hyperplasia

scientific article published on 02 December 2020

CO as a cellular signaling molecule

scientific article

CX3CL1 up-regulation is associated with recruitment of CX3CR1+ mononuclear phagocytes and T lymphocytes in the lungs during cigarette smoke-induced emphysema

scientific article published on 4 September 2008

Carbon Monoxide Confers Protection in Sepsis by Enhancing Beclin 1-Dependent Autophagy and Phagocytosis ⬇️

scientific article published on 05 October 2013

Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators

scientific article published on 10 August 2016

Carbon Monoxide Inhalation Protects Rat Intestinal Grafts from Ischemia/Reperfusion Injury ⬇️

scientific article published on October 1, 2003

Carbon Monoxide Protects against Hyperoxia-induced Endothelial Cell Apoptosis by Inhibiting Reactive Oxygen Species Formation

scientific article published in Journal of Biological Chemistry

Carbon Monoxide in Lung Cell Physiology and Disease

scientific article

Carbon monoxide activates autophagy via mitochondrial reactive oxygen species formation

scientific article published on 25 March 2011

Carbon monoxide and bilirubin: potential therapies for pulmonary/vascular injury and disease

scientific article

Carbon monoxide in exhaled breath testing and therapeutics ⬇️

scientific article published on February 27, 2013

Carbon monoxide in sepsis

scientific article published on November 2007

Carbon monoxide in the treatment of sepsis

scientific article

Carbon monoxide induces cytoprotection in rat orthotopic lung transplantation via anti-inflammatory and anti-apoptotic effects

scientific article published on July 2003

Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3.

scientific article published on 23 October 2002

Carbon monoxide inhibits IL-17-induced IL-6 production through the MAPK pathway in human pulmonary epithelial cells

scientific article published in August 2005

Carbon monoxide inhibits T lymphocyte proliferation via caspase-dependent pathway

scientific article

Carbon monoxide inhibits human airway smooth muscle cell proliferation via mitogen-activated protein kinase pathway

scientific article published in November 2002

Carbon monoxide modulates alpha-smooth muscle actin and small proline rich-1a expression in fibrosis

scientific article published on 18 December 2008

Carbon monoxide modulates endotoxin-induced production of granulocyte macrophage colony-stimulating factor in macrophages

scientific article published on 01 December 2002

Carbon monoxide negatively regulates NLRP3 inflammasome activation in macrophages

scientific article published on 13 March 2015

Carbon monoxide prevents ventilator-induced lung injury via caveolin-1.

scientific article

Carbon monoxide promotes Fas/CD95-induced apoptosis in Jurkat cells

scientific article published on 27 July 2004

Carbon monoxide protection against endotoxic shock involves reciprocal effects on iNOS in the lung and liver

scientific article published on 4 March 2004

Carbon monoxide protects against liver failure through nitric oxide-induced heme oxygenase 1.

scientific article

Carbon monoxide protects against ventilator-induced lung injury via PPAR-gamma and inhibition of Egr-1.

scientific article published on 20 March 2008

Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury

scientific article published on 21 January 2003

Carbon monoxide suppresses bleomycin-induced lung fibrosis

scientific article

Carbon monoxide-dependent signaling

scientific article

Carbon monoxide-dependent signaling

scientific article published on 01 January 2001

Carbon monoxide: present and future indications for a medical gas ⬇️

scientific article (publication date: March 2013)

Carbon monoxide: to boldly go where NO has gone before

scientific article published on 20 April 2004

Caveolae compartmentalization of heme oxygenase-1 in endothelial cells

scientific journal article

Caveolin-1 confers antiinflammatory effects in murine macrophages via the MKK3/p38 MAPK pathway

scientific article published on 15 December 2005

Caveolin-1 expression by means of p38beta mitogen-activated protein kinase mediates the antiproliferative effect of carbon monoxide

scientific journal article

Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2)

scientific article

Caveolin-1 mediates Fas–BID signaling in hyperoxia-induced apoptosis ⬇️

scientific article published on March 5, 2011

Caveolin-1 regulates the secretion and cytoprotection of Cyr61 in hyperoxic cell death

scientific article

Caveolin-1 stops profibrogenic signaling?

scientific article published on 22 February 2008

Caveolin-1: a critical regulator of lung fibrosis in idiopathic pulmonary fibrosis

scientific article published on 18 December 2006

Caveolin-1: a critical regulator of lung injury ⬇️

scientific article published on November 19, 2010

Caveolin-1: a critical regulator of pulmonary vascular architecture and nitric oxide bioavailability in pulmonary hypertension

scientific article published on 22 February 2008

Cecal ligation and puncture-induced sepsis as a model to study autophagy in mice

scientific article

Cell-cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1.

scientific article

Cellular and humoral autoreactivity in idiopathic pulmonary fibrosis

scientific article published on 01 August 2007

Characterization of macroautophagic flux in vivo using a leupeptin-based assay

scientific article

Cigarette smoke stimulates matrix metalloproteinase-2 activity via EGR-1 in human lung fibroblasts

scientific article published on 10 November 2006

Cigarette smoke-initiated autoimmunity facilitates sensitisation to elastin-induced COPD-like pathologies in mice

scientific article published on 04 May 2020

Circadian rhythm reprogramming during lung inflammation

scientific article

Circulating Mitochondrial DNA as Predictor of Mortality in Critically Ill Patients: A Systematic Review of Clinical Studies

scientific article published on 02 August 2019

Circulating RIPK3 levels are associated with mortality and organ failure during critical illness

scientific article published on 12 July 2018

Circulating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validation

scientific article (publication date: December 2013)

Comparison of qSOFA and SIRS for predicting adverse outcomes of patients with suspicion of sepsis outside the intensive care unit.

scientific article published on 26 March 2017

Comprehensive analysis of gene expression on GOLD-2 Versus GOLD-0 smokers reveals novel genes important in the pathogenesis of COPD.

scientific article

Comprehensive gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease

scholarly article

Correction: Caveolin-1 inhibits expression of antioxidant enzymes through direct interaction with nuclear erythroid 2 p45-related factor-2 (Nrf2)

scientific article published on 01 July 2020

Cross Talk between Autophagy and Apoptosis in Pulmonary Hypertension ⬇️

scientific article published on October 1, 2012

Cyr61 protects against hyperoxia-induced cell death via Akt pathway in pulmonary epithelial cells

scientific article published on 16 June 2005

Cytokine signatures of end organ injury in COVID-19

scientific article published on 15 June 2021

Cytoprotection of heme oxygenase-1/carbon monoxide in lung injury

scientific article

Cytoprotective and anti-inflammatory actions of carbon monoxide in organ injury and sepsis models

scientific article published on January 2007

DNA Methylation is Predictive of Mortality in Current and Former Smokers

scientific article published on 29 January 2020

DNA methylation profiling in human lung tissue identifies genes associated with COPD.

scientific article published on 26 August 2016

DROSHA-Dependent AIM2 Inflammasome Activation Contributes to Lung Inflammation during Idiopathic Pulmonary Fibrosis

scientific article published on 20 August 2019

Dampening insulin signaling by an NLRP3 'meta-flammasome' ⬇️

scientific article published on 01 May 2011

Danger Signals in the ICU.

scientific article published on 13 February 2018

Deacetylation of p53 induces autophagy by suppressing Bmf expression

scientific journal article

Deadly triplex: smoke, autophagy and apoptosis

scientific article published on 01 April 2011

Deficiency in the c-Jun NH2-terminal kinase signaling pathway confers susceptibility to hyperoxic lung injury in mice

scientific article published on 21 March 2003

Deletion of caveolin-1 protects against oxidative lung injury via up-regulation of heme oxygenase-1

scientific article published on 6 March 2008

Depletion of pulmonary EC-SOD after exposure to hyperoxia

scientific article published in October 2002

Detection of Rheumatoid Arthritis-Interstitial Lung Disease Is Enhanced by Serum Biomarkers.

scientific article published on June 2015

Determination of Early Immune Function in Sepsis and Its Influence on Organ Dysfunction - Is a More Pragmatic Outcome on the Horizon?

scientific article published on 20 March 2018

Developing a Culture of Mentorship to Strengthen Academic Medical Centers

scientific article published on 01 May 2019

Differential modulation by exogenous carbon monoxide of TNF-alpha stimulated mitogen-activated protein kinases in rat pulmonary artery endothelial cells

scientific article published on 01 April 2002

Discovery of the gene signature for acute lung injury in patients with sepsis

scientific article published on 27 January 2009

Diurnal Rhythms Spatially and Temporally Organize Autophagy

article published in 2019

Effect of Neutropenic Critical Illness on Development and Prognosis of Acute Respiratory Distress Syndrome

scientific article published on 28 September 2020

Effect of early versus late or no tracheostomy on mortality and pneumonia of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis.

scientific article published on February 2015

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

scientific article

Eliminating Medical School Debt: A Dean and Geriatrician's View From Opposite Ends of the Training Pipeline

scientific article published on 31 December 2019

Emerging role of carbon monoxide in physiologic and pathophysiologic states

scientific article published on 01 April 2002

Emerging role of selective autophagy in human diseases

scientific article

Enhanced nitric oxide production associated with airway hyporesponsiveness in the absence of IL-10.

scientific article published on 23 December 2004

Epithelial cell mitochondrial dysfunction and PINK1 are induced by transforming growth factor-beta1 in pulmonary fibrosis

scientific article published on 18 March 2015

Evaluation of inhaled carbon monoxide as an anti-inflammatory therapy in a nonhuman primate model of lung inflammation ⬇️

scientific article published on August 20, 2010

FLIP inhibits endothelial cell apoptosis during hyperoxia by suppressing Bax.

scientific article published on 28 February 2007

FLIP protects against hypoxia/reoxygenation-induced endothelial cell apoptosis by inhibiting Bax activation

scientific article

Fatty acid synthesis and NLRP3-inflammasome

scientific article published on 3 July 2015

Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner

scientific article published on August 2009

Functional impact of a spectrum of interstitial lung abnormalities in rheumatoid arthritis

scientific article

Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue

scientific article published on 13 March 2017

Functional significance of apoptosis in chronic obstructive pulmonary disease

scientific article published on December 2007

GLUT1-dependent glycolysis regulates exacerbation of fibrosis via AIM2 inflammasome activation

scientific article published on 10 December 2019

Gene expression analysis uncovers novel hedgehog interacting protein (HHIP) effects in human bronchial epithelial cells

scientific article published on March 2013

Gene expression profiling in chronic obstructive pulmonary disease

scientific article published on 01 February 2008

Gene expression profiling of target genes in ventilator-induced lung injury

scientific article published on 28 March 2006

Genetically manipulated mouse models of lung disease: potential and pitfalls ⬇️

scientific article published on December 23, 2011

Global gene expression profiles reveal pathways related to the pathogenesis of chronic obstructive pulmonary disease

scientific article published on 01 February 2005

Glucose Transporter 1-Dependent Glycolysis Is Increased during Aging-Related Lung Fibrosis, and Phloretin Inhibits Lung Fibrosis

scientific article published on 20 December 2016

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

Heart allograft protection with low-dose carbon monoxide inhalation: effects on inflammatory mediators and alloreactive T-cell responses

scientific article published on 01 January 2006

Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1.

scientific article published in August 2005

Heat-shock proteins: new keys to the development of cytoprotective therapies

scientific article published on October 2006

Heme Oxygenase-1/CO as Protective Mediators in Cigarette Smoke- Induced Lung Cell Injury and Chronic Obstructive Pulmonary Disease ⬇️

scientific article published on May 1, 2012

Heme oxygenase-1 and carbon monoxide in pulmonary medicine

scientific article

Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease

scientific article

Heme oxygenase-1/carbon monoxide: from basic science to therapeutic applications

scientific article

Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy

scientific article published on 17 July 2009

Heme oxygenase-1/carbon monoxide: novel therapeutic strategies in critical care medicine

scientific article published on December 2010

Heme oxygenase-1: from bench to bedside

scientific article

Heme oxygenase-1: molecular mechanisms of gene expression in oxygen-related stress

scientific article

Heme oxygenase-1: redox regulation of a stress protein in lung and cell culture models

scientific article

Heme oxygenase-1: the "emerging molecule" has arrived

scientific article (publication date: July 2002)

Heme oxygenase/carbon monoxide signaling pathways: regulation and functional significance

scientific article

Hemodynamic and molecular response to intermittent hypoxia (IH) versus continuous hypoxia (CH) in normal humans

scientific article published in February 2007

Hepatocyte growth factor protects against hypoxia/reoxygenation-induced apoptosis in endothelial cells

scientific article published on 18 November 2003

Heteroplasmy concordance between mitochondrial DNA and RNA

scientific article published on 10 September 2019

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction

scientific article

Human Lung DNA Methylation Quantitative Trait Loci Colocalize with COPD Genome-wide Association Loci

scientific article

Hyperoxia-Induced LC3B Interacts with the Fas Apoptotic Pathway in Epithelial Cell Death ⬇️

scientific article published on November 17, 2011

Hypoxia-inducible Factor-1 Mediates Transcriptional Activation of the Heme Oxygenase-1 Gene in Response to Hypoxia

article

Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP.

scientific article

Identifying targets for COPD treatment through gene expression analyses. ⬇️

scientific article published on January 2008

Impaired oxidative phosphorylation regulates necroptosis in human lung epithelial cells

scientific article published on 14 July 2015

In Reply to Patel et al

scientific article published on 01 April 2020

Inducing hypoxemia in healthy humans: a method for intermittently lowering arterial blood oxygenation during physiological studies

scientific article published on 01 January 2008

Inflammasome-regulated cytokines are critical mediators of acute lung injury

scientific article

Inhaled CO in the treatment of acute lung injury

scientific article published on 08 February 2008

Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Unique Proresolving Mediator–Heme Oxygenase-1 Circuits ⬇️

scientific article published on May 6, 2013

Inhaled carbon monoxide confers antiinflammatory effects against ventilator-induced lung injury.

scientific article

Inhaled carbon monoxide suppresses the development of postoperative ileus in the murine small intestine

scientific article published in February 2003

Inhaled hydrogen sulfide protects against ventilator-induced lung injury

scientific article published on 01 July 2010

Insulin-like growth factor binding protein 5 induces skin fibrosis: A novel murine model for dermal fibrosis

scientific article published on 01 September 2006

Insulin-like growth factor-binding protein-5 induces pulmonary fibrosis and triggers mononuclear cellular infiltration

scientific article published on November 2006

Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene

scientific article published on October 2009

Integrative "omic" analysis of experimental bacteremia identifies a metabolic signature that distinguishes human sepsis from systemic inflammatory response syndromes

scientific article

Integrins αvβ5 and αvβ6 Mediate IL-4-Induced Collective Migration in Human Airway Epithelial Cells

scientific article published on 01 April 2019

Interaction of caveolin-1 with ATG12-ATG5 system suppresses autophagy in lung epithelial cells

scientific article published on 11 April 2014

Inverse association of plasma IL-13 and inflammatory chemokines with lung function impairment in stable COPD: a cross-sectional cohort study

scientific article

Isolation of Mouse Respiratory Epithelial Cells and Exposure to Experimental Cigarette Smoke at Air Liquid Interface ⬇️

scientific article published on February 21, 2011

Lipid-soluble components in cigarette smoke induce mitochondrial production of reactive oxygen species in lung epithelial cells

scientific article published on May 2009

Loss of red cell chemokine scavenging promotes transfusion-related lung inflammation

scientific article published on 08 December 2008

Low Dose Carbon Monoxide Exposure in Idiopathic Pulmonary Fibrosis Produces a CO Signature Comprised of Oxidative Phosphorylation Genes

scientific article published on 15 October 2019

Low-dose carbon monoxide inhalation prevents development of chronic allograft nephropathy

scientific article published on 30 August 2005

Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts

scientific article published on 01 August 2006

Low-dose carbon monoxide reduces airway hyperresponsiveness in mice

scientific article published in August 2003

Lung lymphatic thrombosis and dysfunction caused by cigarette smoke exposure precedes emphysema in mice

scientific article published on 23 March 2022

MAPK pathway mediates EGR-1-HSP70-dependent cigarette smoke-induced chemokine production

scientific article published on May 2007

MTOR suppresses autophagy-mediated production of IL25 in allergic airway inflammation

scientific article published on 18 October 2020

Macrolides protect against Pseudomonas aeruginosa infection via inhibition of inflammasomes.

scientific article published on 6 July 2017

Mechanisms of cell death in oxidative stress

scientific article published on January 2007

Meeting the challenges of medical student mental health and well-being today

scientific article published on 01 March 2020

Mesenchymal Stromal Cells Deficient in Autophagy Proteins Are Susceptible to Oxidative Injury and Mitochondrial Dysfunction.

scientific article published on 16 September 2016

Metabolites Associated With Malnutrition in the Intensive Care Unit Are Also Associated With 28-Day Mortality.

scientific article

Metabolome alterations in severe critical illness and vitamin D status.

scientific article

Metabolomic derangements are associated with mortality in critically ill adult patients

scientific article published on 30 January 2014

Midkine: In the Middle of the Pathogenesis of Acute Respiratory Distress Syndrome-associated Lung Fibrosis?

scientific article published in August 2015

Mitochondria in lung biology and pathology: more than just a powerhouse

scientific article

Mitochondria in lung disease

scientific article

Mitochondria: commanders of innate immunity and disease? ⬇️

scientific article published on 03 December 2011

Mitochondria: sensors and mediators of innate immune receptor signaling.

scientific article published on 08 June 2013

Mitochondrial DNA in Sepsis

scientific article published on 27 May 2017

Mitochondrial Dysfunction as a Pathogenic Mediator of Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis

scientific article published on 01 December 2018

Mitochondrial dysfunction induces formation of lipid droplets as a generalized response to stress

scientific article published on 22 September 2013

Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice

scientific article published on 11 January 2016

Mitochondrial localization and function of heme oxygenase-1 in cigarette smoke-induced cell death

scientific article published in November 2006

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis

scientific article published on 29 July 2019

Mitogen activated protein kinase (MAPK) pathway regulates heme oxygenase-1 gene expression by hypoxia in vascular cells

scientific article published in August 2002

Mitogen-activated protein kinases regulate HO-1 gene transcription after ischemia-reperfusion lung injury

scientific journal article

Mitogen-activated protein kinases regulate susceptibility to ventilator-induced lung injury

scientific article (publication date: 2008)

Mitophagy-dependent necroptosis contributes to the pathogenesis of COPD

scientific article

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

Molecular regulation of autophagy and its implications for metabolic diseases

scientific article published on July 2014

N-Glycosylation Regulates Chitinase 3-like-1 and IL-13 Ligand Binding to IL-13 Receptor α2

scientific article published on 13 May 2020

NLRP3 Inflammasome Activation in Aged Macrophages is diminished during Streptococcus pneumoniae Infection

scientific article published on 2 November 2017

NLRP3 Inflammasome Deficiency Protects Against Microbial Sepsis via Increased Lipoxin B4 Synthesis

scientific article published on 28 February 2017

NOX4-dependent fatty acid oxidation promotes NLRP3 inflammasome activation in macrophages

scientific article published on 25 July 2016

Necroptosis: a crucial pathogenic mediator of human disease

scientific article published on 08 August 2019

Necrotic Cell Death in Response to Oxidant Stress Involves the Activation of the Apoptogenic Caspase-8/Bid Pathway ⬇️

scientific article published on May 15, 2003

Network analysis of temporal effects of intermittent and sustained hypoxia on rat lungs

scientific article published on 30 September 2008

Nitric oxide-deficiency regulates hepatic heme oxygenase-1.

scientific article published on 3 December 2007

Nitrite potently inhibits hypoxic and inflammatory pulmonary arterial hypertension and smooth muscle proliferation via xanthine oxidoreductase-dependent nitric oxide generation

scientific article published on 21 December 2009

Non-invasive measurements of exhaled NO and CO associated with methacholine responses in mice

scientific article published on 27 May 2008

Nucleotide-Binding Oligomerization Domain Protein 2 Deficiency Enhances Neointimal Formation in Response to Vascular Injury ⬇️

scientific article published on November 1, 2011

Objectively Measured Chronic Lung Injury on Chest CT

scientific article published on 22 June 2019

Paneth cells as a site of origin for intestinal inflammation.

scientific article

Pathways of cell signaling in hyperoxia

scientific article

Persistent severe acute respiratory distress syndrome for the prognostic enrichment of trials

scientific article published on 27 January 2020

Plasma mitochondrial DNA and metabolomic alterations in severe critical illness

scientific article published on 29 December 2018

Plasma surfactant protein-D as a diagnostic biomarker for acute respiratory distress syndrome: validation in US and Korean cohorts

scientific article published on 15 December 2017

Profibrogenic phenotype in caveolin-1 deficiency via differential regulation of STAT-1/3 proteins

scientific article

Protective effect of carbon monoxide in transplantation

scientific article published on July 2006

Protective effect of carbon monoxide inhalation for cold-preserved small intestinal grafts

scientific article published on 01 August 2003

Protective functions of heme oxygenase-1 and carbon monoxide in the respiratory system

scientific article published on December 2007

Protein kinase C alpha and zeta differentially regulate death-inducing signaling complex formation in cigarette smoke extract-induced apoptosis

scientific article

RETRACTED: Effect of early versus late or no tracheostomy on mortality of critically ill patients receiving mechanical ventilation: a systematic review and meta-analysis

retracted scientific article

RIPK3 promotes sepsis-induced acute kidney injury via mitochondrial dysfunction

scientific article

Rapidly improving acute respiratory distress syndrome in therapeutic randomized controlled trials

scientific article published on 22 October 2018

Reactive oxygen species and extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase mediate hyperoxia-induced cell death in lung epithelium

scientific article published on March 2003

Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung Disease

scientific article

Regulation and Functional Significance of Autophagy in Respiratory Cell Biology and Disease ⬇️

scientific article published on September 13, 2012

Regulation of IL-1beta -induced GM-CSF production in human airway smooth muscle cells by carbon monoxide

scientific article published on 23 August 2002

Regulation of autophagy in oxygen-dependent cellular stress

scientific article published on January 1, 2013

Retinoic acid-related orphan receptor-α is induced in the setting of DNA damage and promotes pulmonary emphysema

scientific article published on 28 June 2012

SESN2/sestrin2 suppresses sepsis by inducing mitophagy and inhibiting NLRP3 activation in macrophages

scientific article published on 23 June 2016

Shaping the Path for a Global Oncology Academic Career

scientific article published on 01 July 2019

Short-term Exposure to Ambient Fine Particulate Matter Increases Hospitalizations and Mortality in COPD: A Systematic Review and Meta-analysis

scientific article published on 25 June 2015

Sphingolipid regulation of lung epithelial cell mitophagy and necroptosis during cigarette smoke exposure

scientific article published in December 2017

Sphingosine 1-phosphate rescues canine LPS-induced acute lung injury and alters systemic inflammatory cytokine production in vivo

scientific article published on 11 October 2008

Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation

scientific article

Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1

scientific article published on 11 July 2003

TGF-beta1 stimulates HO-1 via the p38 mitogen-activated protein kinase in A549 pulmonary epithelial cells

scientific article published on November 2002

TLR4 deficiency promotes autophagy during cigarette smoke-induced pulmonary emphysema ⬇️

scientific article published on September 14, 2012

Targeting heme oxygenase-1 and carbon monoxide for therapeutic modulation of inflammation

scientific article published on 23 June 2015

Temporal trends of outcomes of neutropenic patients with ARDS enrolled in therapeutic clinical trials

scientific article published on 09 October 2020

Testing the rebound peer review concept

scientific article published on 13 July 2013

The IRONy of Iron-overload and Iron-deficiency in Chronic Obstructive Pulmonary Disease.

scientific article

The Intersection Of Aging Biology and The Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

scientific article

The NASA Twins Study: A multidimensional analysis of a year-long human spaceflight

scientific article

The Role of Danger Signals in the Pathogenesis and Perpetuation of Critical Illness

scientific article published on 4 October 2017

The Roles of Mitochondrial Damage-Associated Molecular Patterns in Diseases

scientific article

The emerging importance of autophagy in pulmonary diseases

scientific article

The fibrotic phenotype induced by IGFBP-5 is regulated by MAPK activation and egr-1-dependent and -independent mechanisms

scientific article

The heme oxygenase-1/carbon monoxide pathway suppresses TLR4 signaling by regulating the interaction of TLR4 with caveolin-1.

scientific article published in March 2009

The impact of autophagy on cell death modalities.

scientific article published on 04 February 2014

The influence of radiographic phenotype and smoking status on peripheral blood biomarker patterns in chronic obstructive pulmonary disease

scientific article

The regulation of glucose-6-phosphatase and phosphoenolpyruvate carboxykinase by autophagy in low-glycolytic hepatocellular carcinoma cells

scientific article published on 30 May 2015

The role of necroptosis in pulmonary diseases

scientific article published on 7 June 2016

The saga of leucine zippers continues: in response to oxidative stress

scientific article published in February 2002

Therapeutic applications of carbon monoxide in lung disease

scientific article

UCP2-induced fatty acid synthase promotes NLRP3 inflammasome activation during sepsis

scientific article

Unsupervised Analysis of Transcriptomics in Bacterial Sepsis Across Multiple Datasets Reveals Three Robust Clusters.

scientific article published on 13 March 2018

Very Short Mitochondrial DNA Fragments and Heteroplasmy in Human Plasma

scientific article

mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation.

scientific article published on 25 June 2015

p62 Sequestosome 1/Light Chain 3b Complex Confers Cytoprotection on Lung Epithelial Cells after Hyperoxia ⬇️

scientific article published on April 1, 2013

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