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List of works by Isabelle Treilleux

17β-estradiol inhibits spreading of metastatic cells from granulosa cell tumors through a non-genomic mechanism involving GPER1

scientific article published on 30 March 2015

A functional interplay between ZNF217 and estrogen receptor alpha exists in luminal breast cancers

scientific article

A whole-genome sequence and transcriptome perspective on HER2-positive breast cancers

scientific article published on 13 July 2016

ADP ribosylation factor like 2 (Arl2) regulates breast tumor aggressivity in immunodeficient mice

scientific article

Abstract 1109: The antimicrobial peptide LL37 activates plasmacytoid dendritic cells in breast cancer

Abstract 2780: Tyro3 and Axl receptors tyrosine kinase as potential therapeutic targets in leiomyosarcoma

Abstract LB-253: A comprehensive evaluation of immune checkpoints ligands (ICPLs) in more than 1,000 cancer cell lines (CCLs) identifies specific expression patterns

Acinar-to-Ductal Metaplasia Induced by Transforming Growth Factor Beta Facilitates KRASG12D-driven Pancreatic Tumorigenesis.

scientific article published on 31 May 2017

Activation of rapid oestrogen signalling in aggressive human breast cancers

scientific article

Analysis of PI3K/mTOR Pathway Biomarkers and Their Prognostic Value in Women with Hormone Receptor-Positive, HER2-Negative Early Breast Cancer

scientific article published on April 2016

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article published on 01 February 2019

Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: a case series.

scientific article published in May 2009

Breast cancer targeting through inhibition of the endoplasmic reticulum-based apoptosis regulator Nrh/BCL2L10.

scientific article published on 12 January 2018

Breast cancer-derived transforming growth factor-β and tumor necrosis factor-α compromise interferon-α production by tumor-associated plasmacytoid dendritic cells.

scientific article published on 8 March 2013

Breast carcinoma cells promote the differentiation of CD34+ progenitors towards 2 different subpopulations of dendritic cells with CD1a(high)CD86(-)Langerin- and CD1a(+)CD86(+)Langerin+ phenotypes.

scientific article published on July 2004

CD163+ tumor-associated macrophage accumulation in breast cancer patients reflects both local differentiation signals and systemic skewing of monocytes

scientific article published on 13 February 2020

CD208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type II pneumocytes

scientific journal article

CD73 expression and clinical significance in human metastatic melanoma.

scientific article published in June 2018

Clinical outcome of breast cancer in carriers of BRCA1 and BRCA2 mutations according to molecular subtypes

scientific article published on 27 April 2020

Combined proteomic and transcriptomic approaches reveal externalized keratin 8 as a potential therapeutic target involved in invasiveness of head and neck cancers

scientific article published on 30 September 2020

Combining chemotherapeutic agents and netrin-1 interference potentiates cancer cell death

scientific article published on 08 October 2013

Correction: ADP Ribosylation Factor Like 2 (Arl2) Regulates Breast Tumor Aggressivity in Immunodeficient Mice.

scientific article

Correction: Inactivation of TIF1γ Cooperates with KrasG12D to Induce Cystic Tumors of the Pancreas

scientific article published on 6 August 2009

Cost-effectiveness analysis of strategies for HER2 testing of breast cancer patients in France

scientific article published on 01 January 2006

DICER1 and FOXL2 mutations in ovarian sex cord-stromal tumours: a GINECO Group study

scientific article published on 21 July 2015

Dendritic Cell Infiltration and Prognosis of Early Stage Breast Cancer

scientific article published on 01 November 2004

Detailed overview on rare malignant ovarian tumors

scientific article published on 27 February 2020

Disequilibrium of BMP2 levels in the breast stem cell niche launches epithelial transformation by overamplifying BMPR1B cell response

scientific article

EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

scientific article

ERα-36 regulates progesterone receptor activity in breast cancer

scientific article published on 19 May 2020

Early detection of tumor cells by innate immune cells leads to T(reg) recruitment through CCL22 production by tumor cells

scientific article

Ephrin-B3 supports glioblastoma growth by inhibiting apoptosis induced by the dependence receptor EphA4

scientific article

Expression and role of TYRO3 and AXL as potential therapeutical targets in leiomyosarcoma

scientific article published on 12 October 2017

First-line endocrine therapy alone could be a reasonable treatment option for hormone-positive, HER2-positive metastatic breast cancer.

scientific article

Gene expression profile predicts outcome after anthracycline-based adjuvant chemotherapy in early breast cancer

scientific article published on 29 June 2010

Generation of mice with conditionally activated transforming growth factor beta signaling through the TβRI/ALK5 receptor

scientific article published on 01 December 2008

Genetic alterations and tumor immune attack in Yo paraneoplastic cerebellar degeneration

scientific article published on 3 January 2018

High incidence of mammary intraepithelial neoplasia development in Men1-disrupted murine mammary glands.

scientific article

High rate of PIK3CA mutations but no TP53 mutations in low-grade adenosquamous carcinoma of the breast

scientific article published on 07 May 2018

ICOS-ligand expression on plasmacytoid dendritic cells supports breast cancer progression by promoting the accumulation of immunosuppressive CD4+ T cells

scientific article published in October 2012

IFN-III is selectively produced by cDC1 and predicts good clinical outcome in breast cancer

scientific article published on 17 April 2020

Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer

scientific article

Impact of a second opinion using expression and molecular analysis of FOXL2 for sex cord-stromal tumors. A study of the GINECO group & the TMRO network

scientific article published on 22 October 2013

Impaired IFN- Production by Plasmacytoid Dendritic Cells Favors Regulatory T-cell Expansion That May Contribute to Breast Cancer Progression

article

Inactivation of TIF1gamma cooperates with Kras to induce cystic tumors of the pancreas

scientific article published on 24 July 2009

Integrated analysis highlights APC11 protein expression as a likely new independent predictive marker for colorectal cancer.

scientific article

International network of cancer genome projects

scientific article

Is surgical biopsy mandatory in case of atypical ductal hyperplasia on 11-gauge core needle biopsy? A retrospective study of 300 patients

scientific article published on 30 June 2008

LKB1 regulates PRMT5 activity in breast cancer

scientific article published on 31 October 2018

LKB1 when associated with methylatedERα is a marker of bad prognosis in breast cancer

scientific article published on 4 March 2014

Landscape of somatic mutations in 560 breast cancer whole-genome sequences

scientific article

Long-term exposure to bisphenol A or benzo(a)pyrene alters the fate of human mammary epithelial stem cells in response to BMP2 and BMP4, by pre-activating BMP signaling

scientific article published on 14 October 2016

Management of patients diagnosed with atypical ductal hyperplasia by vacuum-assisted core biopsy: a prospective assessment of the guidelines used at our institution

scientific article published on 23 January 2014

Management of rare ovarian cancers: the experience of the French website "Observatory for rare malignant tumours of the ovaries" by the GINECO group: interim analysis of the first 100 patients

scientific article published on 30 June 2010

Maternal Tgif is required for vascularization of the embryonic placenta

scientific article

Mechanisms of resistance to endocrine therapies for breast cancer

scientific article

Microtubule-associated parameters as predictive markers of docetaxel activity in advanced breast cancer patients: results of a pilot study

scientific article published on December 2002

Molecular Classification of Endometrial Stromal Sarcomas Using RNA Sequencing Defines Nosological and Prognostic Subgroups with Different Natural History

scientific article published on 11 September 2020

Molecular characterization of anastrozole resistance in breast cancer: pivotal role of the Akt/mTOR pathway in the emergence of de novo or acquired resistance and importance of combining the allosteric Akt inhibitor MK-2206 with an aromatase inhibit

scientific article published on 2 May 2013

Multidisciplinarity and medical decision, impact for patients with cancer: sociological assessment of two tumour committees' organization

scientific article published in April 2012

Mutational characterization of individual breast tumors: TP53 and PI3K pathway genes are frequently and distinctively mutated in different subtypes

scientific article published on 22 April 2011

Netrin-1 expression confers a selective advantage for tumor cell survival in metastatic breast cancer

scientific article

New developments in treatment of ovarian carcinoma: focus on trabectedin

scientific article

New therapeutical strategies in metastatic hormone-dependent breast cancer

scientific article

Non-canonical NOTCH3 signalling limits tumour angiogenesis.

scientific article published on 18 July 2017

Oestrogen Non-Genomic Signalling is Activated in Tamoxifen-Resistant Breast Cancer

scientific article published on 05 June 2019

Pancreatic Neuroendocrine Carcinoma Metastatic to the Breast as Part of the Multiple Endocrine Neoplasia Type 1 Syndrome

scientific article published on 01 January 1997

Phenotypic discordance between primary and metastatic breast cancer in the large-scale real-life multicenter French ESME cohort

scientific article published on 16 April 2021

Plasmacytoid dendritic cells infiltrating ovarian cancer are associated with poor prognosis

scientific article published on May 2012

Predicting everolimus treatment efficacy in patients with advanced endometrial carcinoma: a GINECO group study.

scientific article

Primary ovarian borderline tumor in the inguinal lymph node.

scientific article published in March 2013

Prognosis of early-onset breast cancer based on BRCA1/2 mutation status in a French population-based cohort and review

scientific article published on 24 October 2006

Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer

scientific article

Publisher Correction: Clinical outcome of breast cancer in carriers of BRCA1 and BRCA2 mutations according to molecular subtypes

scientific article published on 02 November 2020

Quantitative and Functional Alterations of Plasmacytoid Dendritic Cells Contribute to Immune Tolerance in Ovarian Cancer

scientific article published on 22 June 2011

Rare DICER1 and Absent FOXL2 Mutations Characterize Ovarian Juvenile Granulosa Cell Tumors

scientific article published on 08 September 2020

Regulation of estrogen rapid signaling through arginine methylation by PRMT1

scientific article

Regulatory T cells recruited through CCL22/CCR4 are selectively activated in lymphoid infiltrates surrounding primary breast tumors and lead to an adverse clinical outcome.

scientific article published on 24 February 2009

Role of JMJD6 in Breast Tumourigenesis.

scientific article published on 7 May 2015

SMARCA4 inactivation defines a group of undifferentiated thoracic malignancies transcriptionally related to BAF-deficient sarcomas

scientific article published on 7 September 2015

Semaphorin 3E suppresses tumor cell death triggered by the plexin D1 dependence receptor in metastatic breast cancers

scientific article

Silencing of FLRG, an Antagonist of Activin, Inhibits Human Breast Tumor Cell Growth

scientific article published in August 2007

Surgical Management of Benign and Borderline Phyllodes Tumors of the Breast

scientific article

TIF1γ interferes with TGFβ1/SMAD4 signaling to promote poor outcome in operable breast cancer patients.

scientific article published on 4 June 2015

TIF1γ requires sumoylation to exert its repressive activity on TGFβ signaling.

scientific article published on 20 June 2013

The Bone Morphogenetic Protein Signaling Inhibitor LDN-193189 Enhances Metastasis Development in Mice ⬇️

scientific article published on 19 June 2019

The arginine methyltransferase PRMT1 regulates IGF-1 signaling in breast cancer

scientific article published on 28 January 2019

The conditional expression of KRAS G12D in mouse pancreas induces disorganization of endocrine islets prior the onset of ductal pre-cancerous lesions.

scientific article published on 18 February 2013

The critical role of the ZNF217 oncogene in promoting breast cancer metastasis to the bone.

scientific article published on 16 February 2017

Tif1γ is essential for the terminal differentiation of mammary alveolar epithelial cells and for lactation through SMAD4 inhibition

scientific article published on 15 November 2012

Tif1γ suppresses murine pancreatic tumoral transformation by a Smad4-independent pathway

scientific article

Tumor promotion by intratumoral plasmacytoid dendritic cells is reversed by TLR7 ligand treatment

scientific article published on 30 May 2013

Uncovering the Translational Regulatory Activity of the Tumor Suppressor BRCA1

scientific article published on 10 April 2020

ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion ⬇️

scientific article published on May 16, 2012

[Adjuvant treatments in breast cancer: interest of completion of axillary dissection in case of micrometastases or isolated tumor cells in sentinel lymph node]

scientific article published on 01 April 2012

[Antihormonal therapy in breast cancer and mTOR inhibitors]

scientific article published on 01 December 2011

[Neoadjuvant chemotherapy and ovarian cancer]

scientific article published on 01 July 2006

[Nice-Saint-Paul de Vence 2020 recommendations for clinical practice: Management of metastatic and/or relapsing endometrial cancer]

scientific article published on 18 September 2020

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