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List of works by Ryan E Bash

Combination therapy with potent PI3K and MAPK inhibitors overcomes adaptive kinome resistance to single agents in preclinical models of glioblastoma.

scientific article published on 30 March 2017

Combined kinase inhibitors of MEK1/2 and either PI3K or PDGFR are efficacious in intracranial triple-negative breast cancer.

scientific article published on 9 May 2017

Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation but resistant to temozolomide.

scientific article published on 28 January 2016

Efficacy of Carboplatin Alone and in Combination with ABT888 in Intracranial Murine Models of BRCA-Mutated and BRCA-Wild-Type Triple-Negative Breast Cancer

scientific article

Genomic profiles of low-grade murine gliomas evolve during progression to glioblastoma.

scientific article published on 7 April 2017

Modeling astrocytoma pathogenesis in vitro and in vivo using cortical astrocytes or neural stem cells from conditional, genetically engineered mice

scientific article published on 12 August 2014

PIK3CA missense mutations promote glioblastoma pathogenesis, but do not enhance targeted PI3K inhibition

scientific article published in PLoS ONE

Pharmacokinetics and efficacy of PEGylated liposomal doxorubicin in an intracranial model of breast cancer.

scientific article

Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model.

scientific article published on 13 June 2016

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