List of works by Ginette McKercher

A Simple Variable Number of Tandem Repeat-Based Genotyping Strategy for the Detection of Handling Errors and Validation of Sample Identity in Biobanks

scientific article published on 21 June 2016

An NS3 serine protease inhibitor abrogates replication of subgenomic hepatitis C virus RNA.

scientific article published on 19 March 2003

Benzimidazole Thumb Pocket I finger-loop inhibitors of HCV NS5B polymerase: improved drug-like properties through C-2 SAR in three sub-series

scientific article published on 6 February 2010

Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase

scientific article published on 27 September 2005

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

article

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents

scientific article published on 10 April 2014

Discovery of BI 207524, an indole diamide NS5B thumb pocket 1 inhibitor with improved potency for the potential treatment of chronic hepatitis C virus infection

scientific article published on 25 November 2014

Discovery of a novel series of non-nucleoside thumb pocket 2 HCV NS5B polymerase inhibitors

scientific article

Discovery of the first thumb pocket 1 NS5B polymerase inhibitor (BILB 1941) with demonstrated antiviral activity in patients chronically infected with genotype 1 hepatitis C virus (HCV).

scientific article published on 16 August 2012

Hyperplasie bénigne et cancer de la prostate : hormones stéroïdiennes et facteurs de croissance ⬇️

journal article from 'médecine/sciences' published in 1993

Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: from benzimidazole to indole scaffolds.

scientific article published on October 2006

Integrated strategies for identifying leads that target the NS3 helicase of the hepatitis C virus

scientific article

Internal initiation sites of de novo RNA synthesis within the hepatitis C virus polypyrimidine tract

scientific article published in July 2002

Molecular dynamics simulations and structure-based rational design lead to allosteric HCV NS5B polymerase thumb pocket 2 inhibitor with picomolar cellular replicon potency

scientific article

N-Acetamideindolecarboxylic acid allosteric 'finger-loop' inhibitors of the hepatitis C virus NS5B polymerase: discovery and initial optimization studies

scientific article

Non-nucleoside benzimidazole-based allosteric inhibitors of the hepatitis C virus NS5B polymerase: inhibition of subgenomic hepatitis C virus RNA replicons in Huh-7 cells

scientific article published on December 2004

Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives

scientific article

Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery of benzimidazole 5-carboxylic amide derivatives with low-nanomolar potency

scientific article published on February 2004

Optimization of the 2014 Gleason grade grouping in a Canadian cohort of patients with localized prostate cancer

scientific article published on 11 September 2018

Psychosocial adjustment to a prostate cancer diagnosis in a cohort of radical prostatectomy patients in Quebec, Canada

scientific article published on 27 February 2019

Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate

scientific article published on 22 January 2004

Strategies for biochemical and pathologic quality assurance in a large multi-institutional biorepository; The experience of the PROCURE Quebec Prostate Cancer Biobank

scientific article published on October 2013

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The relationship between body-mass index, physical activity, and pathologic and clinical outcomes after radical prostatectomy for prostate cancer

scientific article published on 22 August 2018

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