Search filters

List of works by Ying Hefner

Adaptation to the coupling of glycolysis to toxic methylglyoxal production in tpiA deletion strains of Escherichia coli requires synchronized and counterintuitive genetic changes

scientific article published on 26 May 2018

Adaptive evolution reveals a tradeoff between growth rate and oxidative stress during naphthoquinone-based aerobic respiration

scientific article published on 25 November 2019

Adaptive laboratory evolution of Escherichia coli under acid stress

scientific article published on 18 October 2019

Adaptive laboratory evolution resolves energy depletion to maintain high aromatic metabolite phenotypes in Escherichia coli strains lacking the Phosphotransferase System

scientific article published on 15 June 2018

Cellular responses to reactive oxygen species are predicted from molecular mechanisms

scientific article published on 03 July 2019

Enzyme promiscuity shapes adaptation to novel growth substrates

scientific article published on 08 April 2019

Evolution of gene knockout strains of E. coli reveal regulatory architectures governed by metabolism

scientific article published in Nature Communications

Growth Adaptation of and Deletion Strains Diverges From a Similar Initial Perturbation of the Transcriptome

article published in 2018

Kinetic profiling of metabolic specialists demonstrates stability and consistency of in vivo enzyme turnover numbers

scientific article published on 01 September 2020

Metabolic and genetic basis for auxotrophies in Gram-negative species

scientific article published on 04 March 2020

Multiple Optimal Phenotypes Overcome Redox and Glycolytic Intermediate Metabolite Imbalances in Escherichia coli pgi Knockout Evolutions

scientific article published on 17 September 2018

Pseudogene repair driven by selection pressure applied in experimental evolution

scientific article published on 28 January 2019

Reframing gene essentiality in terms of adaptive flexibility

article