List of works - Brian J Bacskai

A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice

scientific article published on October 2009

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

scientific article

Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide

scientific article

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain

scientific article

Behavioral deficits, early gliosis, dysmyelination and synaptic dysfunction in a mouse model of mucolipidosis IV.

scientific article

Caspase activation precedes and leads to tangles

scientific article

Changes in the progression of amyloid deposition in APP/PS mice after overexpression of different ApoE isoforms through intraventricular injection of an adeno-associated virus serotype 4

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

scientific article published on August 2005

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

scientific article

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model

scientific article

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

scientific article published on 01 January 2008

Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease

scientific article published on February 2012

Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease.

scientific article published in January 2006

Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging

scientific article

Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo

scientific article

Neurofibrillary tangles remain functionally integrated in cortical networks

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

scientific article published on 6 November 2008

Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease

scientific article

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

scientific article published on February 2008

Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice

scientific article published on April 2013

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain

scientific article published on 21 March 2017

Stable size distribution of amyloid plaques over the course of Alzheimer disease

scientific article

Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy

scientific article

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy

scientific article published in January 2008

List of works by Brian J Bacskai

A reporter of local dendritic translocation shows plaque- related loss of neural system function in APP-transgenic mice

Amyloid beta induces the morphological neurodegenerative triad of spine loss, dendritic simplification, and neuritic dystrophies through calcineurin activation

Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide

Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain

Behavioral deficits, early gliosis, dysmyelination and synaptic dysfunction in a mouse model of mucolipidosis IV.

Caspase activation precedes and leads to tangles

Changes in the progression of amyloid deposition in APP/PS mice after overexpression of different ApoE isoforms through intraventricular injection of an adeno-associated virus serotype 4

Dendritic spine abnormalities in amyloid precursor protein transgenic mice demonstrated by gene transfer and intravital multiphoton microscopy

Differential effect of three-repeat and four-repeat tau on mitochondrial axonal transport

Impaired spine stability underlies plaque-related spine loss in an Alzheimer's disease mouse model

In Vivo Imaging Reveals Dissociation between Caspase Activation and Acute Neuronal Death in Tangle-Bearing Neurons

Inhibition of the NFAT pathway alleviates amyloid β neurotoxicity in a mouse model of Alzheimer's disease

Kinetics of cerebral amyloid angiopathy progression in a transgenic mouse model of Alzheimer disease.

Monitoring protein aggregation and toxicity in Alzheimer's disease mouse models using in vivo imaging

Neurofibrillary tangle-bearing neurons are functionally integrated in cortical circuits in vivo

Neurofibrillary tangles remain functionally integrated in cortical networks

Passive immunotherapy rapidly increases structural plasticity in a mouse model of Alzheimer disease

Progressive Neuronal Pathology and Synaptic Loss Induced by Prediabetes and Type 2 Diabetes in a Mouse Model of Alzheimer's Disease

Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease

Rapid β-amyloid deposition and cognitive impairment after cholinergic denervation in APP/PS1 mice

Soluble oligomeric amyloid-β induces calcium dyshomeostasis that precedes synapse loss in the living mouse brain

Stable size distribution of amyloid plaques over the course of Alzheimer disease

Tau causes synapse loss without disrupting calcium homeostasis in the rTg4510 model of tauopathy

Two postprocessing techniques for the elimination of background autofluorescence for fluorescence lifetime imaging microscopy