List of works - Adolfo A Ferrando

A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia

scientific article published on 03 May 2016

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

scientific article

Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas

scientific article published on 06 January 2017

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

scientific article

CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia

scientific article published on 06 April 2009

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia.

scientific article

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes

scholarly article

ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding.

scientific article published on 20 November 2007

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

scientific article published on 17 January 2018

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

scientific article

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

scientific article

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

scientific article published on 19 October 2020

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

scientific article published on 21 September 2016

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

scientific article published on 16 September 2007

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

scholarly article

PHF6 mutations in T-cell acute lymphoblastic leukemia

scientific article (publication date: 14 March 2010)

ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing data

scientific article

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia

scientific article

Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol

scientific article published on 27 July 2009

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

scientific article published on 12 January 2014

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

scientific article

The TLX1 oncogene drives aneuploidy in T cell transformation

scientific article

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome

scientific article

WT1 mutations in T-ALL

scientific article published on 03 June 2009

List of works by Adolfo A Ferrando

A Case of T-cell Acute Lymphoblastic Leukemia Relapsed As Myeloid Acute Leukemia

A NOTCH1-driven MYC enhancer promotes T cell development, transformation and acute lymphoblastic leukemia

Activating mutations and translocations in the guanine exchange factor VAV1 in peripheral T-cell lymphomas

Activating mutations in the NT5C2 nucleotidase gene drive chemotherapy resistance in relapsed ALL.

CSL-MAML-dependent Notch1 signaling controls T lineage-specific IL-7R{alpha} gene expression in early human thymopoiesis and leukemia

CSL–MAML-dependent Notch1 signaling controls T lineage–specific IL-7Rα gene expression in early human thymopoiesis and leukemia.

ChIP-on-chip significance analysis reveals large-scale binding and regulation by human transcription factor oncogenes

ChIP-on-chip significance analysis reveals ubiquitous transcription factor binding.

Clonal evolution mechanisms in NT5C2 mutant-relapsed acute lymphoblastic leukaemia

Direct reversal of glucocorticoid resistance by AKT inhibition in acute lymphoblastic leukemia

Metabolic reprogramming induces resistance to anti-NOTCH1 therapies in T cell acute lymphoblastic leukemia

Mutational and functional genetics mapping of chemotherapy resistance mechanisms in relapsed acute lymphoblastic leukemia

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

PHF6 mutations in T-cell acute lymphoblastic leukemia

ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing data

Preclinical analysis of the γ-secretase inhibitor PF-03084014 in combination with glucocorticoids in T-cell acute lymphoblastic leukemia

Prognostic implications of NOTCH1 and FBXW7 mutations in adults with T-cell acute lymphoblastic leukemia treated on the MRC UKALLXII/ECOG E2993 protocol

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas

Structure and Mechanisms of NT5C2 Mutations Driving Thiopurine Resistance in Relapsed Lymphoblastic Leukemia

T-cell acute lymphoblastic leukemia in adults: clinical features, immunophenotype, cytogenetics, and outcome from the large randomized prospective trial (UKALL XII/ECOG 2993)

The TLX1 oncogene drives aneuploidy in T cell transformation

The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome

WT1 mutations in T-ALL