Search filters

List of works by Sayuko Kobes

A Genome-Wide Association Study Using a Custom Genotyping Array Identifies Variants in GPR158 Associated With Reduced Energy Expenditure in American Indians

scientific article published on 5 May 2017

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants

scientific article published on 10 May 2017

A Search for Variants Associated With Young-Onset Type 2 Diabetes in American Indians in a 100K Genotyping Array

scientific article published on 10 September 2007

A cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians

scientific article published on 6 February 2015

A genome-wide association study in American Indians implicates DNER as a susceptibility locus for type 2 diabetes

scientific journal article

A genome-wide association study of BMI in American Indians

scientific article published on 23 June 2011

A trans-ancestral meta-analysis of genome-wide association studies reveals loci associated with childhood obesity

scientific article published on 01 October 2019

ABCC8 R1420H Loss-of-Function Variant in a Southwest American Indian Community: Association With Increased Birth Weight and Doubled Risk of Type 2 Diabetes

scientific article

An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects

scientific article

Analysis of SLC16A11 Variants in 12,811 American Indians: Genotype-Obesity Interaction for Type 2 Diabetes and an Association With RNASEK Expression

scientific article published on 20 October 2015

Assessing FOXO1A as a potential susceptibility locus for type 2 diabetes and obesity in American Indians

scientific article

Assessing accuracy of genotype imputation in American Indians

scientific article

Assessing the Role of 98 Established Loci for BMI in American Indians

scientific article published on 18 March 2019

Assessing variation across 8 established East Asian loci for type 2 diabetes mellitus in American Indians: Suggestive evidence for new sex-specific diabetes signals in GLIS3 and ZFAND3.

scientific article published on 8 November 2016

Assessment of established HDL-C loci for association with HDL-C levels and type 2 diabetes in Pima Indians

scientific article published on 15 December 2015

Association analyses of variants in the DIO2 gene with early-onset type 2 diabetes mellitus in Pima Indians

scientific article published on 5 December 2011

Association analysis of Krüppel-like factor 11 variants with type 2 diabetes in Pima Indians

scientific article published on July 2008

Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians

scientific article

CHRM3 gene variation is associated with decreased acute insulin secretion and increased risk for early-onset type 2 diabetes in Pima Indians.

scientific article

Common genetic variation in and near the melanocortin 4 receptor gene (MC4R) is associated with body mass index in American Indian adults and children

scientific article

Common genetic variation in the glucokinase gene (GCK) is associated with type 2 diabetes and rates of carbohydrate oxidation and energy expenditure

scientific article

Common variation in SIM1 is reproducibly associated with BMI in Pima Indians

scientific article published on 28 April 2009

Differential expression of matrix metalloproteinase 3 (MMP3) in preadipocytes/stromal vascular cells from nonobese nondiabetic versus obese nondiabetic Pima Indians.

scientific article

Evaluation of A2BP1 as an obesity gene ⬇️

scientific article

Evidence for a Role of LPGAT1 in Influencing BMI and Percent Body Fat in Native Americans

scholarly article by Michael T. Traurig et al published 22 June 2012 in Obesity

Evidence for a role of LPGAT1 in influencing BMI and percent body fat in Native Americans

scientific article published on January 2013

Functional and association analysis of an Amerindian-derived population-specific p.(Thr280Met) variant in RBPJL, a component of the PTF1 complex

scientific article published on 4 January 2018

Identification and functional analysis of a novel G310D variant in the insulin-like growth factor 1 receptor (IGF1R) gene associated with type 2 diabetes in American Indians

scientific article published on 22 February 2018

Identification of genetic variation that determines human trehalase activity and its association with type 2 diabetes

scientific article published on 7 March 2013

Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation

scientific article

Low Serum Insulinlike Growth Factor II Levels Correlate with High BMI in American Indian Adults

scientific article published on 06 February 2020

Lower metabolic rate in individuals heterozygous for either a frameshift or a functional missense MC4R variant

scientific article published on 03 October 2008

MAP2K3 is associated with body mass index in American Indians and Caucasians and may mediate hypothalamic inflammation

scientific article published on 03 July 2013

PCLO variants are nominally associated with early-onset type 2 diabetes and insulin resistance in Pima Indians

scientific article published on 22 July 2008

SIRT1 is associated with a decrease in acute insulin secretion and a sex specific increase in risk for type 2 diabetes in Pima Indians

scientific article published on 7 August 2011

Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians

scientific article published on 29 April 2013

TCF7L2 is not a major susceptibility gene for type 2 diabetes in Pima Indians: analysis of 3,501 individuals

scientific article

The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3.

scientific article published on 19 April 2016

The role of insulin receptor substrate-1 gene (IRS1) in type 2 diabetes in Pima Indians

scientific article published in December 2003

The transcriptional landscape of age in human peripheral blood

scientific article

Variants associated with type 2 diabetes identified by the transethnic meta-analysis study: assessment in American Indians and evidence for a new signal in LPP.

scientific article

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q, are nominally associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article

Variants in ASK1 are associated with skeletal muscle ASK1 expression, in vivo insulin resistance, and type 2 diabetes in Pima Indians

scientific article

Variants in the Ca V 2.3 (alpha 1E) subunit of voltage-activated Ca2+ channels are associated with insulin resistance and type 2 diabetes in Pima Indians

scientific article (publication date: December 2007)

Variants in the LEPR gene are nominally associated with higher BMI and lower 24-h energy expenditure in Pima Indians

scientific article

Variations in peptide YY and Y2 receptor genes are associated with severe obesity in Pima Indian men.

scientific article

Whole exome sequencing identifies variation in CYB5A and RNF10 associated with adiposity and type 2 diabetes.

scientific article published on 05 December 2013

Paulina is supported by:

About Paulina

Help