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List of works by Russell D Leek

A Phase I First-in-Human Study of Enoticumab (REGN421), a Fully Human Delta-like Ligand 4 (Dll4) Monoclonal Antibody in Patients with Advanced Solid Tumors

scientific article published on 27 February 2015

ADAM10 mediates trastuzumab resistance and is correlated with survival in HER2 positive breast cancer

scientific article

Absence of lymphangiogenesis and intratumoural lymph vessels in human metastatic breast cancer

scientific article published in June 2003

Association between hypoxic volume and underlying hypoxia-induced gene expression in oropharyngeal squamous cell carcinoma

scientific article

Automated uro-oncology data collection: the Cancer Research Uro-Oncology Database

scientific article

Blood vessel invasion and other variables as predictors of long-term survival in Japanese and British patients with primary invasive breast cancer.

scientific article

Bone morphogenetic protein 2 (BMP-2) and induction of tumor angiogenesis

scientific article published on November 2005

CD31 angiogenesis and combined expression of HIF-1α and HIF-2α are prognostic in primary clear-cell renal cell carcinoma (CC-RCC), but HIFα transcriptional products are not: implications for antiangiogenic trials and HIFα biomarker studies in primar

scientific article published on 09 July 2012

Carbonic anhydrase IX promotes tumor growth and necrosis in vivo and inhibition enhances anti-VEGF therapy

scientific article

Cytoplasmic p21WAF1/CIP1 expression is correlated with HER-2/ neu in breast cancer and is an independent predictor of prognosis

scientific article

DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo

scientific article

Delta-like 4 Notch ligand regulates tumor angiogenesis, improves tumor vascular function, and promotes tumor growth in vivo.

scientific article published in December 2007

Dichloroacetate reverses the hypoxic adaptation to bevacizumab and enhances its antitumor effects in mouse xenografts.

scientific article published on 30 January 2013

Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues

scientific article published on October 2002

Effects of HIF-1alpha and HIF2alpha on Growth and Metabolism of Clear-Cell Renal Cell Carcinoma 786-0 Xenografts

scientific article published on 27 June 2010

Expression of bone morphogenetic protein 2 in breast cancer cells inhibits hypoxic cell death

scientific article

Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation.

scientific article published in May 2002

Expression of the forkhead transcription factor FOXP1 is associated with that of estrogen receptor-beta in primary invasive breast carcinomas

scientific article published on 17 November 2007

Expression of vascular notch ligand delta-like 4 and inflammatory markers in breast cancer

scientific article

Functional comparison of Notch ligands in tumour angiogenesis

scholarly article by Chern Ein Oon et al published June 2014 in Asian Pacific journal of tropical disease

Hypoxia-inducible factors HIF-1alpha and HIF-2alpha in head and neck cancer: relationship to tumor biology and treatment outcome in surgically resected patients

scientific article published in May 2002

Intratumoral lymphangiogenesis and lymph node metastasis in head and neck cancer.

scientific article published on March 2002

Isolation of DNA from tumor samples.

scientific article published in January 2006

Isolation of RNA from tumor samples: single-step guanidinium acid-phenol method

scientific article published in January 2006

JMY protein, a regulator of P53 and cytoplasmic actin filaments, is expressed in normal and neoplastic tissues

scientific article published on 04 October 2014

Macrophage infiltration and angiogenesis in human malignancy.

scientific article published on January 2004

Metabolic changes detected by in vivo magnetic resonance studies of HEPA-1 wild-type tumors and tumors deficient in hypoxia-inducible factor-1beta (HIF-1beta): evidence of an anabolic role for the HIF-1 pathway

scientific article published in February 2002

Methods: Using Three-Dimensional Culture (Spheroids) as an In Vitro Model of Tumour Hypoxia

scientific article published on January 2016

New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

scientific article published on 17 June 2010

Noninvasive measurements of capecitabine metabolism in bladder tumors overexpressing thymidine phosphorylase by fluorine-19 magnetic resonance spectroscopy

scientific article published on June 2004

Paracrine effect of GTP cyclohydrolase and angiopoietin-1 interaction in stromal fibroblasts on tumor Tie2 activation and breast cancer growth

scientific article published on 22 January 2016

Prognostic Value of an Activation State Marker for Epidermal Growth Factor Receptor in Tissue Microarrays of Head and Neck Cancer

article

Quantification of Regulatory T Cells Enables the Identification of High-Risk Breast Cancer Patients and Those at Risk of Late Relapse

scientific article published on 01 December 2006

Relation of Erythropoietin and Erythropoietin Receptor Expression to Hypoxia and Anemia in Head and Neck Squamous Cell Carcinoma

article

Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in Human breast cancer

scientific article published on March 2002

Role of Delta-like 4 in Jagged1-induced tumour angiogenesis and tumour growth

scientific article published on 8 April 2017

Roles of tetrahydrobiopterin in promoting tumor angiogenesis

scientific article

The G-protein-coupled receptor CLR is upregulated in an autocrine loop with adrenomedullin in clear cell renal cell carcinoma and associated with poor prognosis

scientific article published on 22 August 2013

The histone demethylase JMJD2B is regulated by estrogen receptor alpha and hypoxia, and is a key mediator of estrogen induced growth

scientific article

The relation between hypoxia-inducible factor (HIF)-1α and HIF-2α expression with anemia and outcome in surgically treated head and neck cancer

article

The role of hypoxia-inducible factor-1 in three-dimensional tumor growth, apoptosis, and regulation by the insulin-signaling pathway

scientific article

The use of bio-metal concentrations correlated with clinical prognostic factors to assess human breast tissues

article by Alia Al-Ebraheem et al published 15 June 2013 in X-Ray Spectrometry

Tumor-associated macrophages in breast cancer.

scientific article

Why some tumours trigger neovascularisation and others don't: the story thus far.

scientific article published on 12 February 2016

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