List of works by Silvana Savino

A universal vaccine for serogroup B meningococcus

scholarly article

Antigen identification starting from the genome: a "Reverse Vaccinology" approach applied to MenB.

scientific article published in January 2012

Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies

scientific article

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

scientific article

Development of an influenza virus protein array using Sortagging technology

scientific article published on 25 May 2012

Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.

scientific article

Exploring host-pathogen interactions through genome wide protein microarray analysis

scientific article

Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined

scientific article published on 17 February 2016

GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA).

scientific article published in August 2002

HadA is an atypical new multifunctional trimeric coiled-coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells

scientific article published on 12 March 2009

Identification of Neisseria meningitidis nonlipopolysaccharide ligands for class A macrophage scavenger receptor by using a novel assay

scientific article published on September 2006

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

scientific article

Lectin Activity of the TcdA and TcdB Toxins of Clostridium difficile

scientific article published on 21 February 2019

Lectin activity of Pseudomonas aeruginosa vaccine candidates PSE17-1, PSE41-5 and PSE54

scientific article published on 03 April 2019

Lectin activity of the pneumococcal pilin proteins

scientific article

NadA, a novel vaccine candidate of Neisseria meningitidis

scientific article

NarE: a novel ADP-ribosyltransferase from Neisseria meningitidis

scientific article published in November 2003

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

scientific article

Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages

scientific article

Protective efficacy induced by recombinant Clostridium difficile toxin fragments

scientific article published on 28 May 2013

Putative vaccine antigens from Neisseria meningitidis recognized by serum antibodies of young children convalescing after meningococcal disease

scientific article published on 09 September 2004

Rational design of a meningococcal antigen inducing broad protective immunity

scientific article

Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant

scientific article

Role of ARF6, Rab11 and external Hsp90 in the trafficking and recycling of recombinant-soluble Neisseria meningitidis adhesin A (rNadA) in human epithelial cells

scientific article (publication date: 2014)

RrgB321, a fusion protein of the three variants of the pneumococcal pilus backbone RrgB, is protective in vivo and elicits opsonic antibodies

scientific article published on 14 November 2011

SR-A, MARCO and TLRs differentially recognise selected surface proteins from Neisseria meningitidis: an example of fine specificity in microbial ligand recognition by innate immune receptors

scientific article published on 11 September 2008

Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis

scientific article

Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis

scientific article

Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2

scientific article

Structural characterization of a cross-protective natural chimera of factor H binding protein from meningococcal serogroup B strain NL096

scientific article published on 18 April 2022

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP.

scientific article published on 13 January 2014

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

scientific article

The factor H binding protein of Neisseria meningitidis interacts with xenosiderophores in vitro.

scientific article

The region comprising amino acids 100 to 255 of Neisseria meningitidis lipoprotein GNA 1870 elicits bactericidal antibodies

scientific article published in February 2005

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties

Vaccination against Neisseria meningitidis using three variants of the lipoprotein GNA1870

scientific article

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

scientific article

Vir90, a virulence-activated gene coding for a Bordetella pertussis iron-regulated outer membrane protein

scientific article published on July 2003

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