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List of works by Maria Scarselli

A naturally occurring single-residue mutation in the translocator domain of Neisseria meningitidis NhhA affects trimerization, surface localization, and adhesive capabilities

scientific article

Approach to discover T- and B-cell antigens of intracellular pathogens applied to the design of Chlamydia trachomatis vaccines

scientific article

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin

scientific article published on 30 March 2016

Characterization of diverse subvariants of the meningococcal factor H (fH) binding protein for their ability to bind fH, to mediate serum resistance, and to induce bactericidal antibodies

scientific article

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

scientific article

Diversity of cwp loci in clinical isolates of Clostridium difficile

scientific article published on 30 May 2013

Dual role of the colonization factor CD2831 in Clostridium difficile pathogenesis

article published in 2019

Epitope mapping of a bactericidal monoclonal antibody against the factor H binding protein of Neisseria meningitidis.

scientific article

Expression of factor H binding protein in meningococcal strains can vary at least 15-fold and is genetically determined

scientific article published on 17 February 2016

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome"

scientific article

Genome-based vaccine development: a short cut for the future

scientific article published on January 2009

Genome‑based vaccine development: A short cut for the future ⬇️

scientific article published on May 1, 2008

Genomic approach for analysis of surface proteins in Chlamydia pneumoniae

scientific article

HadA is an atypical new multifunctional trimeric coiled-coil adhesin of Haemophilus influenzae biogroup aegyptius, which promotes entry into host cells

scientific article published on 12 March 2009

Identification of a novel zinc metalloprotease through a global analysis of Clostridium difficile extracellular proteins

scientific article

Identification of a universal Group B streptococcus vaccine by multiple genome screen

scientific article

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

scientific article

Lectin Activity of the TcdA and TcdB Toxins of Clostridium difficile

scientific article published on 21 February 2019

Mapping of theNeisseria meningitidisNadA Cell-Binding Site: Relevance of Predicted α-Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions ⬇️

scientific article published on October 22, 2010

Metal ion complexation and folding of linear peptides.

scientific article published in May 2002

Molecular Engineering of Ghfp, the Gonococcal Orthologue of Neisseria meningitidis Factor H Binding Protein

scientific article published on 6 May 2015

Multi high-throughput approach for highly selective identification of vaccine candidates: the Group A Streptococcus case.

scientific article

NMR and MD studies on the interaction between ligand peptides and alpha-bungarotoxin.

scientific article

NMR structure of alpha-bungarotoxin free and bound to a mimotope of the nicotinic acetylcholine receptor

scientific article

NMR studies of protein hydration and TEMPOL accessibility.

scientific article

NMR studies of the inclusion complex between beta-cyclodextrin and paroxetine.

scientific article

NMR studies on Ni(II) induced cyclization of a histidine-tagged peptide.

scientific article

NarE: a novel ADP-ribosyltransferase from Neisseria meningitidis

scientific article published in November 2003

Native State Organization of Outer Membrane Porins Unraveled by HDx-MS.

scientific article published on 5 April 2018

Neisseria meningitidis App, a new adhesin with autocatalytic serine protease activity

scientific article published on April 2003

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

scientific article

Neisseria meningitidis NhhA is a multifunctional trimeric autotransporter adhesin.

scientific article

Neisseria meningitidis factor H-binding protein bound to monoclonal antibody JAR5: implications for antibody synergy.

scientific article

Neisseria meningitidis factor H-binding protein fHbp: a key virulence factor and vaccine antigen.

scientific article

Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages

scientific article

Peptide-protein interactions studied by surface plasmon and nuclear magnetic resonances

scientific article published in January 2002

Protective efficacy induced by recombinant Clostridium difficile toxin fragments

scientific article published on 28 May 2013

Rational design of a meningococcal antigen inducing broad protective immunity

scientific article

Recombinant Clostridium difficile toxin fragments as carrier protein for PSII surface polysaccharide preserve their neutralizing activity

scientific article

Solution Structure of the Factor H-binding Protein, a Survival Factor and Protective Antigen of Neisseria meningitidis

scientific article

Solution structure of the immunodominant domain of protective antigen GNA1870 of Neisseria meningitidis

scientific article

Structural and functional characterization of the Streptococcus pneumoniae RrgB pilus backbone D1 domain

scientific article

Structural basis for cooperativity of human monoclonal antibodies to meningococcal factor H-binding protein

scientific article published on 26 June 2019

Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile

scientific article

Structural vaccinology: a three-dimensional view for vaccine development

scientific article

Structurally driven selection of human hepatitis C virus mimotopes.

scientific article

Structure and function correlations between the rat liver threonine deaminase and aminotransferases.

scientific article published on January 2003

Structure of the C-terminal Domain of Neisseria Heparin Binding Antigen (NHBA), One of the Main Antigens of a Novel Vaccine against Neisseria meningitidis

scientific article

Structure of the meningococcal vaccine antigen NadA and epitope mapping of a bactericidal antibody

scientific article

Supramolecular Organization of the Repetitive Backbone Unit of the Streptococcus pneumoniae Pilus

scientific article

Synergic complement-mediated bactericidal activity of monoclonal antibodies with distinct specificity

scientific article published on 17 June 2020

Targeted amino acid substitutions impair streptolysin O toxicity and group A Streptococcus virulence

scientific article published on 8 January 2013

The factor H binding protein of Neisseria meningitidis interacts with xenosiderophores in vitro.

scientific article

The impact of genomics on vaccine design

scientific article

The region comprising amino acids 100 to 255 of Neisseria meningitidis lipoprotein GNA 1870 elicits bactericidal antibodies

scientific article published in February 2005

The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release

scientific article

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

scientific article

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