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List of works by Miles W Carroll

A comparison of host gene expression signatures associated with infection in vitro by the Makona and Ecran (Mayinga) variants of Ebola virus.

scientific article published on 27 February 2017

A cross-reactive human IgA monoclonal antibody blocks SARS-CoV-2 spike-ACE2 interaction

scientific article published on 21 August 2020

A novel vaccine against Crimean-Congo Haemorrhagic Fever protects 100% of animals against lethal challenge in a mouse model

scientific article

A quantitative proteomic analysis of lung epithelial (A549) cells infected with 2009 pandemic influenza A virus using stable isotope labelling with amino acids in cell culture

scientific article published on 14 May 2012

Accounting for population structure reveals ambiguity in the Zaire Ebolavirus reservoir dynamics

scientific article published on 04 March 2020

Amplicon and Metagenomic Analysis of Middle East Respiratory Syndrome (MERS) Coronavirus and the Microbiome in Patients with Severe MERS

scientific article published on 21 July 2021

Amplicon based MinION sequencing of SARS-CoV-2 and metagenomic characterisation of nasopharyngeal swabs from patients with COVID-19

scientific article (preprint)

Amplicon-Based Detection and Sequencing of SARS-CoV-2 in Nasopharyngeal Swabs from Patients With COVID-19 and Identification of Deletions in the Viral Genome That Encode Proteins Involved in Interferon Antagonism

scientific article published on 14 October 2020

Analysis of Diagnostic Findings From the European Mobile Laboratory in Guéckédou, Guinea, March 2014 Through March 2015

scientific article published on 16 September 2016

Analysis of SARS-CoV-2 in Nasopharyngeal Samples from Patients with COVID-19 Illustrates Population Variation and Diverse Phenotypes, Placing the Growth Properties of Variants of Concern in Context with Other Lineages

scientific article published in 2022

Analysis of SARS-CoV-2 known and novel subgenomic mRNAs in cell culture, animal model, and clinical samples using LeTRS, a bioinformatic tool to identify unique sequence identifiers

scientific article published on 01 May 2022

Analysis of an Ebola virus disease survivor whose host and viral markers were predictive of death indicates the effectiveness of medical countermeasures and supportive care

scientific article published on 11 January 2021

Animal models for COVID-19

scientific article published on 23 September 2020

Antibody evasion by the P.1 strain of SARS-CoV-2

scientific article

Antibody testing for COVID-19: A report from the National COVID Scientific Advisory Panel

scientific article published on 20 April 2020

Antiviral Screening of Multiple Compounds against Ebola Virus

scientific article published on 27 October 2016

Assessment of metagenomic Nanopore and Illumina sequencing for recovering whole genome sequences of chikungunya and dengue viruses directly from clinical samples

scientific article published on 01 December 2018

Author Correction: Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 15 October 2020

Avatar Mice Underscore the Role of the T Cell-Dendritic Cell Crosstalk in Ebola Virus Disease and Reveal Mechanisms of Protection in Survivors

scientific article published in 2022

Case study: design and implementation of training for scientists deploying to Ebola diagnostic field laboratories in Sierra Leone: October 2014 to February 2016.

scientific article

Cellular immune response to human influenza viruses differs between H1N1 and H3N2 subtypes in the ferret lung

scientific article published in PLoS ONE

Characterisation of the transcriptome and proteome of SARS-CoV-2 reveals a cell passage induced in-frame deletion of the furin-like cleavage site from the spike glycoprotein

scientific article published on 28 July 2020

Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage si

scientific article published on 25 March 2020

Chloroquine inhibited Ebola virus replication in vitro but failed to protect against infection and disease in the in vivo guinea pig model

scientific article

Cloned Defective Interfering Influenza Virus Protects Ferrets from Pandemic 2009 Influenza A Virus and Allows Protective Immunity to Be Established ⬇️

scientific article published on December 12, 2012

Comparison of rhesus and cynomolgus macaques as an infection model for COVID-19

scientific article

Comparison of the protection of ferrets against pandemic 2009 influenza A virus (H1N1) by 244 DI influenza virus and oseltamivir ⬇️

scientific article published on October 4, 2012

Convalescent plasma donors show enhanced cross‐reactive neutralizing antibody response to antigenic variants of SARS‐CoV‐2 following immunization

scientific article published in 2022

Correction: Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

scientific article published on 5 April 2016

Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation

scientific article published on 28 January 2014

Deep Sequencing of RNA from Blood and Oral Swab Samples Reveals the Presence of Nucleic Acid from a Number of Pathogens in Patients with Acute Ebola Virus Disease and Is Consistent with Bacterial Translocation across the Gut.

scientific article published on July 2017

Detection of Viral Pathogens With Multiplex Nanopore MinION Sequencing: Be Careful With Cross-Talk

scientific article published in 2018

Development of a Cost-effective Ovine Polyclonal Antibody-Based Product, EBOTAb, to Treat Ebola Virus Infection

scientific article published on 28 December 2015

Development of immunohistochemistry and in situ hybridisation for the detection of SARS-CoV and SARS-CoV-2 in formalin-fixed paraffin-embedded specimens

scientific article published on 14 December 2020

Development of vaccines against Crimean-Congo haemorrhagic fever virus

scientific article

Different features of Vδ2 T and NK cells in fatal and non-fatal human Ebola infections

scientific article

Divergent trajectories of antiviral memory after SARS-CoV-2 infection

scientific article published on 10 March 2022

Dose-Dependent Response to Infection with Ebola Virus in the Ferret Model and Evidence of Viral Evolution in the Eye

scientific article published on 29 September 2021

Dose-dependent response to infection with SARS-CoV-2 in the ferret model and evidence of protective immunity

scientific article

Early transmission and case fatality of Ebola virus at the index site of the 2013-16 west African Ebola outbreak: a cross-sectional seroprevalence survey

article

Ebola Virus Disease Survivors Show More Efficient Antibody Immunity than Vaccinees Despite Similar Levels of Circulating Immunoglobulins

scientific article published on 20 August 2020

Ebola Virus Persistence in Breast Milk After No Reported Illness: A Likely Source of Virus Transmission From Mother to Child

scientific article

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

scientific article

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

scientific article

Elucidating variations in the nucleotide sequence of Ebola virus associated with increasing pathogenicity ⬇️

scientific article

Elucidation of the Cellular Interactome of Ebola Virus Nucleoprotein and Identification of Therapeutic Targets ⬇️

scientific article published on 27 October 2016

Elucidation of the Ebola virus VP24 cellular interactome and disruption of virus biology through targeted inhibition of host-cell protein function ⬇️

scientific article published on 23 October 2014

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

scientific article published on 27 July 2020

Evidence of escape of SARS-CoV-2 variant B.1.351 from natural and vaccine induced sera

scientific article published in February 2021

Evolution of 2009 H1N1 influenza viruses during the pandemic correlates with increased viral pathogenicity and transmissibility in the ferret model

scientific article

Expanding the Arterivirus Host Spectrum: Olivier's Shrew Virus 1, A Novel Arterivirus Discovered in African Giant Shrews

scientific article published in Scientific Reports

Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea

scientific article

Fatal COVID-19 outcomes are associated with an antibody response targeting epitopes shared with endemic coronaviruses

scientific article published in 2022

Field investigation with real-time virus genetic characterisation support of a cluster of Ebola virus disease cases in Dubréka, Guinea, April to June 2015.

scientific article published in March 2018

Heat Shock Protein 70 Family Members Interact with Crimean-Congo Hemorrhagic Fever Virus and Hazara Virus Nucleocapsid Proteins and Perform a Functional Role in the Nairovirus Replication Cycle ⬇️

scientific article (publication date: 15 October 2016)

Heterosubtypic cross-protection correlates with cross-reactive interferon-gamma-secreting lymphocytes in the ferret model of influenza

Human Diversity of Killer Cell Immunoglobulin-Like Receptors and Human Leukocyte Antigen Class I Alleles and Ebola Virus Disease Outcomes

scientific article published on 01 January 2021

Humoral and cellular immune response induced by rVSVΔG-ZEBOV-GP vaccine among frontline workers during the 2013-2016 West Africa Ebola outbreak in Guinea

scientific article published on 01 June 2020

Identification of important amino acid replacements in the 2013-2016 Ebola virus outbreak

Immunogenicity of a DNA vaccine candidate for COVID-19

scientific article published on 20 May 2020

Immunological and pathological outcomes of SARS-CoV-2 challenge following formalin-inactivated vaccine in ferrets and rhesus macaques

scientific article published on 10 September 2021

Induction of protective immunity against H1N1 influenza A(H1N1)pdm09 with spray-dried and electron-beam sterilised vaccines in non-human primates

scientific article published on 11 March 2014

Influenza A Virus Challenge Models in Cynomolgus Macaques Using the Authentic Inhaled Aerosol and Intra-Nasal Routes of Infection

scientific article (publication date: 2016)

Investigating the Cellular Transcriptomic Response Induced by the Makona Variant of Ebola Virus in Differentiated THP-1 Cells

scientific article published on 04 November 2019

Laboratory findings, compassionate use of favipiravir, and outcome in patients with Ebola virus disease, Guinea, 2015 — a retrospective observational study

scholarly article by Romy Kerber et al published 21 February 2019 in Journal of Infectious Diseases

Longitudinal antibody and T cell responses in Ebola virus disease survivors and contacts: an observational cohort study

scientific article published on 13 October 2020

Low dose influenza virus challenge in the ferret leads to increased virus shedding and greater sensitivity to oseltamivir.

scientific article

Metagenomic Nanopore Sequencing of Influenza Virus Direct from Clinical Respiratory Samples

scientific article published on 23 December 2019

Metagenomic Nanopore sequencing of influenza virus direct from clinical respiratory samples

scientific article published on 19 June 2019

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

scientific article (publication date: 9 January 2017)

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples.

scientific article

Nanopore metagenomic sequencing of influenza virus directly from respiratory samples: diagnosis, drug resistance and nosocomial transmission

scientific article published on 23 April 2020

Nanopore metagenomic sequencing to investigate nosocomial transmission of human metapneumovirus from a unique genetic group among haematology patients in the United Kingdom

scientific article published on 22 February 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

scientific article published on 19 June 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

scientific article published on 01 September 2020

Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike

scientific article

Neutralization of SARS-CoV-2 by destruction of the prefusion Spike

scientific article published on 07 May 2020

Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2

scientific article published on 13 July 2020

Persistence and clearance of Ebola virus RNA from seminal fluid of Ebola virus disease survivors: a longitudinal analysis and modelling study

scientific article published on January 2017

Phase 1/2 trial of SARS-CoV-2 vaccine ChAdOx1 nCoV-19 with a booster dose induces multifunctional antibody responses

scientific article

Post-exposure prophylaxis with rVSV-ZEBOV following exposure to a patient with Ebola virus disease relapse in the UK: an operational, safety and immunogenicity report

scientific article published on 30 November 2019

Post-exposure treatment of Ebola virus disease in guinea pigs using EBOTAb, an ovine antibody-based therapeutic

scientific article published on 28 July 2016

Post-exposure treatment of non-human primates lethally infected with Ebola virus with EBOTAb, a purified ovine IgG product

scientific article

Prevalence of antibodies against hantaviruses in serum and saliva of adults living or working on farms in Yorkshire, United Kingdom

scientific article published on 05 February 2014

Prophylactic intranasal administration of a TLR2/6 agonist reduces upper respiratory tract viral shedding in a SARS-CoV-2 challenge ferret model

scientific article published on 03 December 2020

Protective effects of a Modified Vaccinia Ankara-based vaccine candidate against Crimean-Congo Haemorrhagic Fever virus require both cellular and humoral responses

scientific article

Pseudotyping of VSV with Ebola virus glycoprotein is superior to HIV-1 for the assessment of neutralising antibodies

scientific article published on 31 August 2020

Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases ⬇️

scientific article

Real-time, portable genome sequencing for Ebola surveillance

scientific article

Recombinant viral vectors: cancer vaccines

scientific article published on 16 August 2006

Reduced neutralization of SARS-CoV-2 B.1.1.7 variant by convalescent and vaccine sera

scientific article

Reduced neutralization of SARS-CoV-2 B.1.617 by vaccine and convalescent serum

Reply to comment--Clement et al.: (Prevalence of antibodies against hantaviruses in serum and saliva of adults living or working on farms in Yorkshire, United Kingdom).

scientific article

Resurgence of Ebola Virus Disease in Guinea Linked to a Survivor With Virus Persistence in Seminal Fluid for More Than 500 Days

scientific article

SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

scientific article published on 04 January 2022

SARS-CoV-2 RNA detected in blood products from patients with COVID-19 is not associated with infectious virus

scientific article

Safety and immunogenicity of INO-4800 DNA vaccine against SARS-CoV-2: A preliminary report of an open-label, Phase 1 clinical trial

scientific article published on 24 December 2020

Sex practices and awareness of Ebola virus disease among male survivors and their partners in Guinea

scientific article published on 25 September 2017

Structural basis for the neutralization of SARS-CoV-2 by an antibody from a convalescent patient

scientific article published on 31 July 2020

Structures and therapeutic potential of anti-RBD human monoclonal antibodies against SARS-CoV-2

scientific article published on 01 January 2022

Synthetic Heparan Sulfate Mimetic Pixatimod (PG545) Potently Inhibits SARS-CoV-2 By Disrupting The Spike-ACE2 interaction

scientific article

Temporal and spatial analysis of the 2014-2015 Ebola virus outbreak in West Africa

scientific article published on 17 June 2015

The Ministry of Health and Sanitation, Sierra Leone  - Public Health England (MOHS-PHE) Ebola Biobank

scientific article published on 30 October 2019

The antigenic anatomy of SARS-CoV-2 receptor binding domain

scientific article

Therapeutic Monoclonal Antibodies for Ebola Virus Infection Derived from Vaccinated Humans

scientific article published on 01 April 2019

Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

scientific article published on 19 January 2017

UK vaccines network: Mapping priority pathogens of epidemic potential and vaccine pipeline developments

scientific article published on 12 September 2019

Unfractionated heparin inhibits live wild-type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations

scientific article published on 30 October 2020

Unique human immune signature of Ebola virus disease in Guinea

scientific article

Unusual Ebola Virus Chain of Transmission, Conakry, Guinea, 2014-2015

scientific article

Variation around the dominant viral genome sequence contributes to viral load and outcome in patients with Ebola virus disease

scientific article published on 07 September 2020

Viral Evasion of the Complement System and Its Importance for Vaccines and Therapeutics

scientific article published on 09 July 2020

Virus genomes reveal factors that spread and sustained the Ebola epidemic

scientific article (publication date: 12 April 2017)

Virus genomes reveal the factors that spread and sustained the West African Ebola epidemic

article published in 2016

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