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List of works by Jaklien C Leemans

A tissue-specific role for Nlrp3 in tubular epithelial repair after renal ischemia/reperfusion

scientific article published on 11 May 2014

Alveolar macrophages have a protective antiinflammatory role during murine pneumococcal pneumonia

scientific article published on 25 September 2002

CCAAT-enhancer binding protein delta (C/EBPδ) attenuates tubular injury and tubulointerstitial fibrogenesis during chronic obstructive nephropathy

scientific article

CD44 is a macrophage binding site for Mycobacterium tuberculosis that mediates macrophage recruitment and protective immunity against tuberculosis

scientific article

CD44-deficiency attenuates the immunologic responses to LPS and delays the onset of endotoxic shock-induced renal inflammation and dysfunction

scientific article

CD44v3-v10 reduces the profibrotic effects of TGF-β1 and attenuates tubular injury in the early stage of chronic obstructive nephropathy

scientific article published on 11 September 2013

Calcineurin inhibitor Tacrolimus impairs host immune response against urinary tract infection

scientific article published in Scientific Reports

Chemokine expression in renal ischemia/reperfusion injury is most profound during the reparative phase

scientific article

Corrigendum: Effect of TREM-1 blockade and single nucleotide variants in experimental renal injury and kidney transplantation

scientific article published on 15 March 2017

CpG Oligodeoxynucleotides Enhance Host Defense during Murine Tuberculosis ⬇️

scientific article published on January 1, 2002

Deficiency for the chemokine monocyte chemoattractant protein-1 aggravates tubular damage after renal ischemia/reperfusion injury

scientific article published on 13 April 2015

Deletion of NLRX1 increases fatty acid metabolism and prevents diet-induced hepatic steatosis and metabolic syndrome

scientific article published on 4 March 2018

Depletion of Gut Microbiota Protects against Renal Ischemia-Reperfusion Injury

scientific article

Donor and recipient genetic variants in NLRP3 associate with early acute rejection following kidney transplantation

scientific article published on 7 November 2016

Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis

scientific article published on 7 November 2007

Haematopoietic stem cell migration to the ischemic damaged kidney is not altered by manipulating the SDF-1/CXCR4-axis

scientific article published on 16 February 2009

High glucose induces HGF-independent activation of Met receptor in human renal tubular epithelium

scientific article

Host response of platelet-activating factor receptor-deficient mice during pulmonary tuberculosis

scientific article published on August 2003

Hydrogen sulfide-induced hypometabolism prevents renal ischemia/reperfusion injury

scientific article

Increased Circulating and Urinary Levels of Soluble TAM Receptors in Diabetic Nephropathy

scientific article published on 29 June 2017

Lipoteichoic acid and peptidoglycan from Staphylococcus aureus synergistically induce neutrophil influx into the lungs of mice

scientific article

Macrophages play a dual role during pulmonary tuberculosis in mice

scientific article published on 29 November 2004

Metabolic injury-induced NLRP3 inflammasome activation dampens phospholipid degradation

scientific article published on 06 June 2017

Mitochondrial DNA is Released in Urine of Sirs Patients with Acute Kidney Injury and Correlates with Severity of Renal Dysfunction

scientific article published on 23 August 2017

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

scientific article

Nlrp3 is a key modulator of diet-induced nephropathy and renal cholesterol accumulation.

scientific article

Nlrp3 prevents early renal interstitial edema and vascular permeability in unilateral ureteral obstruction

scientific article published on 15 January 2014

No difference in renal injury and fibrosis between wild-type and NOD1/NOD2 double knockout mice with chronic kidney disease induced by ureteral obstruction.

scientific article

Opposite role of CD44-standard and CD44-variant-3 in tubular injury and development of renal fibrosis during chronic obstructive nephropathy

scientific article published on 9 April 2014

Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease ⬇️

scientific article published on October 11, 2012

Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice

scientific article

RAGE Does Not Contribute to Renal Injury and Damage upon Ischemia/Reperfusion-Induced Injury

scientific article published on 04 November 2011

Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney

scientific article

Role of TREM1-DAP12 in renal inflammation during obstructive nephropathy

scientific article

Role of Toll-like receptor 4 in gram-positive and gram-negative pneumonia in mice.

scientific article

S100A8/A9 is not involved in host defense against murine urinary tract infection

scientific article

SDF-1 provides morphological and functional protection against renal ischaemia/reperfusion injury

scientific article published on 2 June 2010

Stem cell factor expression after renal ischemia promotes tubular epithelial survival

scientific article

TLR4 promotes fibrosis but attenuates tubular damage in progressive renal injury

scientific article

TLR9 Mediates Remote Liver Injury following Severe Renal Ischemia Reperfusion

scientific article published on 11 September 2015

TREM-1 and its potential ligands in non-infectious diseases: from biology to clinical perspectives

scientific article published on 25 February 2017

The epidermal growth factor-seven transmembrane (EGF-TM7) receptor CD97 is required for neutrophil migration and host defense

scientific article (publication date: 15 January 2004)

The role of Toll-like receptor 2 in inflammation and fibrosis during progressive renal injury

scientific article

The toll interleukin-1 receptor (IL-1R) 8/single Ig domain IL-1R-related molecule modulates the renal response to bacterial infection

scientific article published on 13 August 2012

Toll-Like Receptor Family Polymorphisms Are Associated with Primary Renal Diseases but Not with Renal Outcomes Following Kidney Transplantation

scientific article

Toll-like receptor 4 plays a protective role in pulmonary tuberculosis in mice

scientific article published in March 2004

Toll-like receptor-4 coordinates the innate immune response of the kidney to renal ischemia/reperfusion injury

scientific article

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