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List of works by Christopher R Bethel

Crystal Structure of KPC-2:  Insights into Carbapenemase Activity in Class A β-Lactamases † , ‡

scientific article

Crystal Structure of a Preacylation Complex of the β-Lactamase Inhibitor Sulbactam Bound to a Sulfenamide Bond-Containing Thiol-β-lactamase

scientific article

Crystal Structures of KPC-2 β-Lactamase in Complex with 3-Nitrophenyl Boronic Acid and the Penam Sulfone PSR-3-226 ⬇️

scientific article published on February 13, 2012

Design and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with a Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) β-Lactamase

scientific article

Design, Synthesis, and Crystal Structures of 6-Alkylidene-2′-Substituted Penicillanic Acid Sulfones as Potent Inhibitors of Acinetobacter baumannii OXA-24 Carbapenemase

scientific article

Enhancing resistance to cephalosporins in class C beta-lactamases: impact of Gly214Glu in CMY-2.

scientific article

Ligand-Dependent Disorder of the   Loop Observed in Extended-Spectrum SHV-Type  -Lactamase

scientific article

Molecular analysis of the simultaneous production of two SHV-type extended-spectrum beta-lactamases in a clinical isolate of Enterobacter cloacae by using single-nucleotide polymorphism genotyping

scientific article published on November 2005

Novel Insights into the Mode of Inhibition of Class A SHV-1  -Lactamases Revealed by Boronic Acid Transition State Inhibitors

scientific article

Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae

scientific article

Penam Sulfones and β-Lactamase Inhibition: SA2-13 and the Importance of the C2 Side Chain Length and Composition

scientific article

Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States

scientific article published on 21 April 2008

Strategic Design of an Effective  -Lactamase Inhibitor: LN-1-255, A 6-ALKYLIDENE-2'-SUBSTITUTED PENICILLIN SULFONE

scientific article

Structures of SHV-1 β-Lactamase with Penem and Penam Sulfone Inhibitors That Form Cyclic Intermediates Stabilized by Carbonyl Conjugation ⬇️

scientific article published on November 8, 2012

β-Lactamase Inhibition by 7-Alkylidenecephalosporin Sulfones: Allylic Transposition and Formation of an Unprecedented Stabilized Acyl-Enzyme

scientific article

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