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List of works by Kristine M Hujer

"Silent" dissemination of Klebsiella pneumoniae isolates bearing K. pneumoniae carbapenemase in a long-term care facility for children and young adults in Northeast Ohio

scientific article

1348. In vitro Activity of Plazomicin, a Next-Generation Aminoglycoside, Against Carbapenemase-Producing Klebsiella pneumoniae

article published in 2018

1351. In vitro Activity of Cefiderocol (S-649266), a Siderophore Cephalosporin, Against Enterobacteriaceae With Defined Extended-Spectrum Β-Lactamases and Carbapenemases

608Can Rapid Molecular Diagnostics Assist in the Choice of b-Lactam Antibiotics? An Analysis of Data from PRIMERS-II of the Antibiotic Resistance Leadership Group (ARLG).

scientific article published in December 2014

687. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Acinetobacter spp

698. In vitro Activity of a New Generation Oxopyrazole Antibiotic Against Multidrug-Resistant Gram-Negative Bacilli

A Prospective Observational Study of the Epidemiology, Management, and Outcomes of Skin and Soft Tissue Infections Due to Carbapenem-Resistant Enterobacteriaceae

scientific article published on 27 July 2017

A Standard Numbering Scheme for Class C β-Lactamases

scientific article published on 21 February 2020

A clinical strain of Escherichia coli possessing CMY-2 plasmid-mediated amp C beta-lactamase: an emerging concern in pediatrics?

scientific article published in January 2002

A comprehensive and contemporary "snapshot" of β-lactamases in carbapenem resistant Acinetobacter baumannii

scientific article published on 16 October 2020

A γ-Lactam Siderophore Antibiotic Effective Against Multidrug-Resistant Gram-Negative Bacilli

scientific article published on 18 May 2020

ACHN-490, a neoglycoside with potent in vitro activity against multidrug-resistant Klebsiella pneumoniae isolates

scientific article published on October 2009

ARGONAUT II - In vitro activity of plazomicin against carbapenemase-producing Klebsiella pneumoniae

scientific article published on 09 March 2020

ARGONAUT-I: Activity of cefiderocol (S-649266), a siderophore cephalosporin, against Gram-negative bacteria including carbapenem resistant nonfermenters and Enterobacteriaceae with defined extended-spectrum β-lactamases and carbapenemases

scientific article published on 21 December 2018

Acinetobacter baumannii isolates from pets and horses in Switzerland: molecular characterization and clinical data

scientific article

Adjunctive transferrin to reduce the emergence of antibiotic resistance in Gram-negative bacteria

scientific article published on 01 September 2019

Amino acid substitutions at Ambler position Gly238 in the SHV-1 beta-lactamase: exploring sequence requirements for resistance to penicillins and cephalosporins

scientific article

An Analysis of the Epidemic of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae: Convergence of Two Evolutionary Mechanisms Creates the "Perfect Storm".

scientific article published on 27 September 2017

Analysis of antibiotic resistance genes in multidrug-resistant Acinetobacter sp. isolates from military and civilian patients treated at the Walter Reed Army Medical Center

scientific article

Antibiotic resistance determinants in Acinetobacter spp and clinical outcomes in patients from a major military treatment facility

scientific article

Antibiotic resistance in the institutionalized elderly

scientific article published on June 2004

Apotransferrin in Combination with Ciprofloxacin Slows Bacterial Replication, Prevents Resistance Amplification, and Increases Antimicrobial Regimen Effect

scientific article published on 25 April 2019

Are Staphylococcus intermedius Infections in Humans Cases of Mistaken Identity? A Case Series and Literature Review

scientific article

Are we ready for novel detection methods to treat respiratory pathogens in hospital-acquired pneumonia?

scientific article

Benefit-risk Evaluation for Diagnostics: A Framework (BED-FRAME).

scientific article

Can Ceftazidime-Avibactam and Aztreonam Overcome β-Lactam Resistance Conferred by Metallo-β-Lactamases in Enterobacteriaceae?

scientific article

Carbapenem-resistant Acinetobacter baumannii and Klebsiella pneumoniae across a hospital system: impact of post-acute care facilities on dissemination

scientific article

Characterization of blaKPC-containing Klebsiella pneumoniae isolates detected in different institutions in the Eastern USA.

scientific article published on 20 January 2009

Colistin Resistance in Carbapenem-Resistant Klebsiella pneumoniae: Laboratory Detection and Impact on Mortality

scientific article published on 10 December 2016

Comparative genome sequence analysis of multidrug-resistant Acinetobacter baumannii

scientific article published on 17 October 2008

Core genome MLST and resistome analysis of Klebsiella pneumoniae using a clinically amenable workflow

scientific article published on 21 January 2020

Correction for Evans et al., "Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III".

scientific article published on June 2017

Draft Genome Sequence of the Clinical Isolate Acinetobacter nosocomialis Strain M2.

scientific article

Elucidating the role of Trp105 in the KPC-2 β-lactamase

scientific article

Emergence of linezolid-resistant Staphylococcus aureus after prolonged treatment of cystic fibrosis patients in Cleveland, Ohio

scientific article

Erratum for "New Insights into Dissemination and Variation of the Health Care-Associated Pathogen Acinetobacter baumannii from Genomic Analysis".

scientific article published on 4 June 2015

Erratum for Wright et al., Population Structure of KPC-Producing Klebsiella pneumoniae Isolates from Midwestern U.S. Hospitals.

scientific article published in October 2014

Evaluation of Sensititre Broth Microdilution Plate for determining the susceptibility of carbapenem-resistant Klebsiella pneumoniae to polymyxins

scientific article

Evaluation of a commercial microarray system for detection of SHV-, TEM-, CTX-M-, and KPC-type beta-lactamase genes in Gram-negative isolates

scientific article

Evaluation of ceftazidime and NXL104 in two murine models of infection due to KPC-producing Klebsiella pneumoniae

scientific article

Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems

scientific article

Extended-spectrum beta-lactamases in Klebsiella pneumoniae bloodstream isolates from seven countries: dominance and widespread prevalence of SHV- and CTX-M-type beta-lactamases

scientific article

Fibrocystin interacts with CAML, a protein involved in Ca2+ signaling

scientific article

Genome Sequences of Two Klebsiella pneumoniae Isolates from Different Geographical Regions, Argentina (Strain JHCK1) and the United States (Strain VA360)

scientific article published on March 2013

Global challenge of multidrug-resistant Acinetobacter baumannii

scientific article

Host fate is rapidly determined by innate effector-microbial interactions during Acinetobacter baumannii bacteremia

scientific article published on 5 November 2014

Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes

scientific article

In vitro activity of antibiotic combinations against multidrug-resistant strains of Acinetobacter baumannii and the effects of their antibiotic resistance determinants ⬇️

scientific article published on January 6, 2012

In vitro activity of fosfomycin against blaKPC-containing Klebsiella pneumoniae isolates, including those nonsusceptible to tigecycline and/or colistin

scientific article

In vivo and in vitro activity of the siderophore monosulfactam BAL30072 against Acinetobacter baumannii

scientific article published on 13 February 2011

Infections caused by fluoroquinolone-resistant Escherichia coli following transrectal ultrasound-guided biopsy of the prostate

scientific article

Informing Antibiotic Treatment Decisions: Evaluating Rapid Molecular Diagnostics To Identify Susceptibility and Resistance to Carbapenems against Acinetobacter spp. in PRIMERS III.

scientific article published on 26 October 2016

Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis

scientific article

Inhibition of OXA-1 beta-lactamase by penems

scientific article

Initial Assessment of the Molecular Epidemiology of blaNDM-1 in Colombia

scientific article published on 11 April 2016

Interaction of the Ca2+-sensing receptor with the inwardly rectifying potassium channels Kir4.1 and Kir4.2 results in inhibition of channel function

scientific article

Interlaboratory reproducibility of DiversiLab rep-PCR typing and clustering of Acinetobacter baumannii isolates ⬇️

scientific article published on September 8, 2011

Longitudinal analysis of the temporal evolution of Acinetobacter baumannii strains in Ohio, USA, by using rapid automated typing methods

scientific article (publication date: 2012)

Molecular analysis of the simultaneous production of two SHV-type extended-spectrum beta-lactamases in a clinical isolate of Enterobacter cloacae by using single-nucleotide polymorphism genotyping

scientific article published on November 2005

Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study

scientific article published on 06 March 2020

Monoclonal Antibody Protects Against Acinetobacter baumannii Infection by Enhancing Bacterial Clearance and Evading Sepsis

scientific article published in August 2017

Multidrug Resistant Pseudomonas aeruginosa Causing Prosthetic Valve Endocarditis: A Genetic-Based Chronicle of Evolving Antibiotic Resistance

scientific article

NDM-5 and OXA-181 Beta-Lactamases, a Significant Threat Continues To Spread in the Americas

scientific article published on May 2017

New insights into dissemination and variation of the health care-associated pathogen Acinetobacter baumannii from genomic analysis

scientific article published on 21 January 2014

Occupational transmission of Acinetobacter baumannii from a United States serviceman wounded in Iraq to a health care worker

scientific article

Outer membrane protein changes and efflux pump expression together may confer resistance to ertapenem in Enterobacter cloacae

scientific article

Performance of the Phoenix bacterial identification system compared with disc diffusion methods for identifying extended-spectrum beta-lactamase, AmpC and KPC producers

scientific article

Population structure of KPC-producing Klebsiella pneumoniae isolates from midwestern U.S. hospitals

scientific article

Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States

scientific article published on 21 April 2008

Rapid Molecular Diagnostics to Inform Empiric Use of Ceftazidime/Avibactam and Ceftolozane/Tazobactam Against Pseudomonas aeruginosa: PRIMERS IV

scientific article published on 01 May 2019

Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II.

scientific article

Rapid determination of quinolone resistance in Acinetobacter spp.

scientific article published on 18 March 2009

Rapid identification of bla KPC-possessing Enterobacteriaceae by PCR/electrospray ionization-mass spectrometry

scientific article published on 10 June 2010

Role of Asp104 in the SHV beta-lactamase

scientific article

Role of ceramide in Ca2+-sensing receptor-induced apoptosis

scientific article

SHV-type extended-spectrum beta-lactamase production is associated with Reduced cefepime susceptibility in Enterobacter cloacae

scientific article

Silencing of filamin A gene expression inhibits Ca2+ -sensing receptor signaling

scientific article published on 24 February 2006

Spread in an Italian hospital of a clonal Acinetobacter baumannii strain producing the TEM-92 extended-spectrum beta-lactamase

scientific article published on 2 April 2007

Strategic Design of an Effective  -Lactamase Inhibitor: LN-1-255, A 6-ALKYLIDENE-2'-SUBSTITUTED PENICILLIN SULFONE

scientific article

Substrate selectivity and a novel role in inhibitor discrimination by residue 237 in the KPC-2 beta-lactamase

scientific article

Targeting Multidrug-Resistant spp.: Sulbactam and the Diazabicyclooctenone β-Lactamase Inhibitor ETX2514 as a Novel Therapeutic Agent

scientific article published on 12 March 2019

The Ca2+-sensing receptor couples to Galpha12/13 to activate phospholipase D in Madin-Darby canine kidney cells

scientific article published on 3 September 2003

The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant

article

The continuing challenge of ESBLs

scientific article

The role of OXA-1 beta-lactamase Asp(66) in the stabilization of the active-site carbamate group and in substrate turnover

scientific article published on March 2008

The role of a second-shell residue in modifying substrate and inhibitor interactions in the SHV beta-lactamase: a study of ambler position Asn276.

scientific article

Understanding resistance to beta-lactams and beta-lactamase inhibitors in the SHV beta-lactamase: lessons from the mutagenesis of SER-130.

scientific article published on 8 October 2003

Unexpected challenges in treating multidrug-resistant Gram-negative bacteria: resistance to ceftazidime-avibactam in archived isolates of Pseudomonas aeruginosa

scientific article

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