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List of works by Raymond Hupperts

A low vitamin D status at diagnosis is associated with an early conversion to secondary progressive multiple sclerosis.

scientific article

Autoantibody profiling in multiple sclerosis reveals novel antigenic candidates

scientific article

Autoantigen induced clonal expansion in immortalized B cells from the peripheral blood of multiple sclerosis patients

scientific article published on 5 June 2013

B Cells Are Multifunctional Players in Multiple Sclerosis Pathogenesis: Insights from Therapeutic Interventions

scientific article

Circulating vitamin D binding protein levels are not associated with relapses or with vitamin D status in multiple sclerosis

scientific article

Comparative effectiveness of glatiramer acetate and interferon beta formulations in relapsing-remitting multiple sclerosis

scientific article published on 5 December 2014

Comparative efficacy of first-line natalizumab vs IFN-β or glatiramer acetate in relapsing MS.

scientific article published on April 2016

Comparative efficacy of switching to natalizumab in active multiple sclerosis

scientific article

Compositional changes of B and T cell subtypes during fingolimod treatment in multiple sclerosis patients: a 12-month follow-up study

scientific article

Compromised CD4+ CD25(high) regulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

scientific article published on 25 September 2007

Contribution of different relapse phenotypes to disability in multiple sclerosis.

scientific article published on 7 April 2016

Defining reliable disability outcomes in multiple sclerosis

scientific article published on 10 September 2015

Defining secondary progressive multiple sclerosis

scientific article published on 7 July 2016

Discontinuing disease-modifying therapy in MS after a prolonged relapse-free period: a propensity score-matched study

scientific article published on 13 June 2016

Drug adherence and multidisciplinary care in patients with multiple sclerosis: Protocol of a prospective, web-based, patient-centred, nation-wide, Dutch cohort study in glatiramer acetate treated patients (CAIR study) ⬇️

scientific article published on March 30, 2011

Effect of vitamin D(3) supplementation on peripheral B cell differentiation and isotype switching in patients with multiple sclerosis

scientific article

Effects of vitamin D on the peripheral adaptive immune system: a review

scientific article published on 18 May 2011

Efficacy of vitamin D3 as add-on therapy in patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon β-1a: a Phase II, multicenter, double-blind, randomized, placebo-controlled trial

scientific article published on 28 May 2011

Evaluating the safety of β-interferons in MS: A series of nested case-control studies

scientific article published on 12 May 2017

Exploring the effect of vitamin D3 supplementation on the anti-EBV antibody response in relapsing-remitting multiple sclerosis.

scientific article

Fatigue and physical disability in patients with multiple sclerosis: a structural equation modeling approach

scientific article

Fingolimod in active multiple sclerosis: an impressive decrease in Gd-enhancing lesions

scientific article

Fluoxetine in progressive multiple sclerosis (FLUOX-PMS): study protocol for a randomized controlled trial.

scientific article published on 25 January 2014

Fok-I vitamin D receptor gene polymorphism (rs10735810) and vitamin D metabolism in multiple sclerosis.

scientific article

Geographical variations in sex ratio trends over time in multiple sclerosis.

scientific article

Highly active immunomodulatory therapy ameliorates accumulation of disability in moderately advanced and advanced multiple sclerosis

scientific article published on 28 September 2016

Illuminating vitamin D effects on B cells--the multiple sclerosis perspective

scientific article published on 30 December 2015

Illuminating vitamin D effects on B-cells - the multiple sclerosis perspective

scientific article published on 05 January 2016

Immune regulatory effects of high dose vitamin D3 supplementation in a randomized controlled trial in relapsing remitting multiple sclerosis patients receiving IFNβ; the SOLARIUM study

scientific article published on 3 October 2016

Increasing age at disability milestones among MS patients in the MSBase Registry

scientific article published on 14 April 2012

Intracellular IL-10 detection in T cells by flowcytometry: the use of protein transport inhibitors revisited

scientific article published on 29 April 2012

Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis

scientific article published on April 2017

Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS

scientific article published on 5 June 2015

Monoclonal antibody therapy in experimental allergic encephalomyelitis and multiple sclerosis

scientific article

Multiple sclerosis in Latin America: A different disease course severity? A collaborative study from the MSBase Registry

scientific article

Network of nuclear receptor ligands in multiple sclerosis: Common pathways and interactions of sex-steroids, corticosteroids and vitamin D3-derived molecules

scientific article

Persistence and adherence in multiple sclerosis patients starting glatiramer acetate treatment: assessment of relationship with care received from multiple disciplines

scientific article published on 24 May 2016

Persistence on therapy and propensity matched outcome comparison of two subcutaneous interferon beta 1a dosages for multiple sclerosis

scientific article

Predictors and dynamics of postpartum relapses in women with multiple sclerosis.

scientific article

Predictors of disability worsening in clinically isolated syndrome.

scientific article published on 27 March 2015

Predictors of relapse and disability progression in MS patients who discontinue disease-modifying therapy

Prevalence of cutaneous adverse events associated with long-term disease-modifying therapy and their impact on health-related quality of life in patients with multiple sclerosis: a cross-sectional study

scientific article

Prolonged-release fampridine and walking and balance in MS: randomised controlled MOBILE trial.

scientific article published on 28 April 2015

Quantifying risk of early relapse in patients with first demyelinating events: Prediction in clinical practice.

scientific article published on 24 November 2016

Reduction in IL-10 producing B cells (Breg) in multiple sclerosis is accompanied by a reduced naïve/memory Breg ratio during a relapse but not in remission

scientific article published on 21 September 2011

Regulatory T cell function correlates with serum 25-hydroxyvitamin D, but not with 1,25-dihydroxyvitamin D, parathyroid hormone and calcium levels in patients with relapsing remitting multiple sclerosis

scientific article published on 6 March 2010

Risk of relapse phenotype recurrence in multiple sclerosis.

scientific article

Safety and T cell modulating effects of high dose vitamin D3 supplementation in multiple sclerosis

scientific article (publication date: 13 December 2010)

Seasonal variation of relapse rate in multiple sclerosis is latitude dependent.

scientific article published on 20 October 2014

Sex as a determinant of relapse incidence and progressive course of multiple sclerosis

scientific article published on 18 October 2013

Th17 expansion in MS patients is counterbalanced by an expanded CD39+ regulatory T cell population during remission but not during relapse

scientific article published on 26 October 2011

The STAR Study: a real-world, international, observational study of the safety and tolerability of, and adherence to, serum-free subcutaneous interferon β-1a in patients with relapsing multiple sclerosis.

scientific article published on 05 May 2014

The effect of oral immunomodulatory therapy on treatment uptake and persistence in multiple sclerosis

scientific article published on 21 July 2015

The effect of postpartum intravenous immunoglobulins on the relapse rate among patients with multiple sclerosis

scientific article

The influence of sex hormones on cytokines in multiple sclerosis and experimental autoimmune encephalomyelitis: a review

scientific article

The psychology of fatigue in patients with multiple sclerosis: a review

scientific article published on 24 September 2008

The relevance of vitamin D receptor gene polymorphisms for vitamin D research in multiple sclerosis

scientific article published on 11 February 2009

Towards personalized therapy for multiple sclerosis: prediction of individual treatment response.

scientific article published in September 2017

Treatment effectiveness of alemtuzumab compared with natalizumab, fingolimod, and interferon beta in relapsing-remitting multiple sclerosis: a cohort study.

scientific article published on 10 February 2017

Vitamin D Status Does Not Affect Disability Progression of Patients with Multiple Sclerosis over Three Year Follow-Up

scientific article

Vitamin D as an immune modulator in multiple sclerosis, a review

scientific article published on 04 January 2008

Vitamin D effects on B cell function in autoimmunity

scientific article published on 24 April 2014

Vitamin D status is positively correlated with regulatory T cell function in patients with multiple sclerosis

scientific article

Vitamin D-related gene expression profiles in immune cells of patients with relapsing remitting multiple sclerosis

scientific article published on 20 April 2011

Vitamin D3 supplementation and the IL-2/IL-2R pathway in multiple sclerosis: Attenuation of progressive disturbances?

scientific article

Vitamin D3 supplementation in multiple sclerosis: Symptoms and biomarkers of depression

scientific article published on 19 April 2017

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