Search filters

List of works by P Patrizia Mangione

A novel mechano-enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

scientific article

A specific nanobody prevents amyloidogenesis of D76N β2-microglobulin in vitro and modifies its tissue distribution in vivo.

scientific article

Amyloid persistence in decellularized liver: biochemical and histopathological characterization.

scientific article published on 8 December 2015

Bifunctional crosslinking ligands for transthyretin

scientific article

Binding of Monovalent and Bivalent Ligands by Transthyretin Causes Different Short- and Long-Distance Conformational Changes

scientific article published on 22 August 2019

Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin.

scientific article published on 7 March 2017

Class I Major Histocompatibility Complex, the Trojan Horse for Secretion of Amyloidogenic β 2 -Microglobulin

scientific article

Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel.

scientific article

Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry: αB-crystallin dissociates β2-microglobulin oligomers.

scientific article published on 03 May 2013

Plasminogen activation triggers transthyretin amyloidogenesis

scientific article published in Journal of Biological Chemistry

Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis

scientific article

Structure, folding dynamics, and amyloidogenesis of D76N β2-microglobulin: roles of shear flow, hydrophobic surfaces, and α-crystallin.

scientific article published on 06 September 2013