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List of works by Eunice L Kwak

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Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

scientific article
Isolation of rare circulating tumour cells in cancer patients by microchip technology

scientific article
ROS1 rearrangements define a unique molecular class of lung cancers

scientific article
Activity and safety of crizotinib in patients with ALK-positive non-small-cell lung cancer: updated results from a phase 1 study

scientific article published on 04 September 2012
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis

scientific article
Irreversible inhibitors of the EGF receptor may circumvent acquired resistance to gefitinib

scientific article
Crizotinib in ALK-rearranged inflammatory myofibroblastic tumor.

scientific article
Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping

scientific article published on December 16, 2011
Efficacy, safety, and potential biomarkers of sunitinib monotherapy in advanced hepatocellular carcinoma: a phase II study

scientific article
MET amplification identifies a small and aggressive subgroup of esophagogastric adenocarcinoma with evidence of responsiveness to crizotinib

scientific article published on 31 October 2011
Activity of crizotinib (PF02341066), a dual mesenchymal-epithelial transition (MET) and anaplastic lymphoma kinase (ALK) inhibitor, in a non-small cell lung cancer patient with de novo MET amplification

scientific article
Combined BRAF and MEK Inhibition With Dabrafenib and Trametinib in BRAF V600-Mutant Colorectal Cancer.

scientific article
Radiological and surgical implications of neoadjuvant treatment with FOLFIRINOX for locally advanced and borderline resectable pancreatic cancer

scientific article
Phase I Study of RO4929097, a Gamma Secretase Inhibitor of Notch Signaling, in Patients With Refractory Metastatic or Locally Advanced Solid Tumors

scientific article published on April 23, 2012
Tumor Heterogeneity and Lesion-Specific Response to Targeted Therapy in Colorectal Cancer

scientific article
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

scientific article
FOLFIRINOX in Locally Advanced Pancreatic Cancer: The Massachusetts General Hospital Cancer Center Experience

scientific article published on May 8, 2013
Phase 1/2 study of everolimus in advanced hepatocellular carcinoma

scientific article
Multi-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma

scientific article published on December 14, 2015
Epidermal growth factor receptor kinase domain mutations in esophageal and pancreatic adenocarcinomas

scientific article published on July 2006
Dose-painted intensity-modulated radiation therapy for anal cancer: a multi-institutional report of acute toxicity and response to therapy

scientific article
Rapid Radiographic and Clinical Improvement After Treatment of a MET-Amplified Recurrent Glioblastoma With a Mesenchymal-Epithelial Transition Inhibitor

scientific article published on December 12, 2011
Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma

scientific article published on January 29, 2014
Rapid and dramatic radiographic and clinical response to an ALK inhibitor (crizotinib, PF02341066) in an ALK translocation-positive patient with non-small cell lung cancer

scientific article published on December 2010
First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer.

scientific article published on 4 February 2015
Mutational analysis and clinical correlation of metastatic colorectal cancer

scientific article published on February 5, 2014
A Phase 1/2 and Biomarker Study of Preoperative Short Course Chemoradiation With Proton Beam Therapy and Capecitabine Followed By Early Surgery for Resectable Pancreatic Ductal Adenocarcinoma

scientific article published on May 24, 2014
Phase I Safety, Pharmacokinetic, and Pharmacodynamic Study of ENMD-2076, a Novel Angiogenic and Aurora Kinase Inhibitor,in Patients with Advanced Solid Tumors

scientific article published on 03 December 2010
Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma

scientific article published on August 5, 2015
Targeted agents: the rules of combination

scientific article published on September 2007
Multicenter phase II study of tivozanib (AV-951) and everolimus (RAD001) for patients with refractory, metastatic colorectal cancer

scientific article
Potent antitumor activity of cabozantinib, a c-MET and VEGFR2 inhibitor, in a colorectal cancer patient-derived tumor explant model.

scientific article
Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer

scientific article
NCCN Task Force Report: mTOR inhibition in solid tumors.

scientific article published on September 2008
Updated long‐term outcomes and prognostic factors for patients with unresectable locally advanced pancreatic cancer treated with intraoperative radiotherapy at the Massachusetts General Hospital, 1978 to 2010

scientific article published on September 4, 2013
Mammary tumorigenesis following transgenic expression of a dominant negative CHK2 mutant

scientific article
Preoperative Cetuximab, Irinotecan, Cisplatin, and Radiation Therapy for Patients With Locally Advanced Esophageal Cancer

scientific article published on February 21, 2013
Long-term outcomes and toxicities of a large cohort of anal cancer patients treated with dose-painted IMRT per RTOG 0529

scientific article published on 06 February 2017
Hereditary colorectal cancer syndromes: an overview

scientific article published on January 2007
Targeted therapies with chemoradiation in esophageal cancer: development and future directions

scientific article published on January 2013
A phase 1 open-label, sequential dose-escalation study investigating the safety, tolerability, and pharmacokinetics of intravenous TLC388 administered to patients with advanced solid tumors

scientific article
Familial Gastric Cancers

scientific article published on September 30, 2015
Delaying chemoradiation until after completion of adjuvant chemotherapy for pancreatic cancer may not impact local control

scientific article published on 09 August 2013
A phase 2 study of oral MKC-1, an inhibitor of importin-β, tubulin, and the mTOR pathway in patients with unresectable or metastatic pancreatic cancer

scientific article published on 29 July 2011

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