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List of works by Erica N Borducchi

Ad26/MVA therapeutic vaccination with TLR7 stimulation in SIV-infected rhesus monkeys

scientific article

Adenovirus Vector-Based Vaccines Confer Maternal-Fetal Protection against Zika Virus Challenge in Pregnant IFN-αβR-/- Mice

scientific article published on 24 October 2019

Adenovirus prime, Env protein boost vaccine protects against neutralization-resistant SIVsmE660 variants in rhesus monkeys

scientific article

Adenovirus serotype 26 and 35 vectors induce simian immunodeficiency virus-specific T lymphocyte responses in foreskin in rhesus monkeys

scientific article published on 15 January 2014

Adenovirus serotype 5 neutralizing antibodies target both hexon and fiber following vaccination and natural infection

scientific article published on 9 November 2011

Adenovirus serotype 5 vaccine vectors trigger IL-27-dependent inhibitory CD4+ T cell responses that impair CD8+ T cell function

scientific article

Adenovirus serotype 5-specific neutralizing antibodies target multiple hexon hypervariable regions

scientific article published on 9 November 2011

Alternative serotype adenovirus vaccine vectors elicit memory T cells with enhanced anamnestic capacity compared to Ad5 vectors

scientific article published on 14 November 2012

An attenuated Listeria monocytogenes vector primes more potent simian immunodeficiency virus-specific mucosal immunity than DNA vaccines in mice

scientific article published on 6 February 2013

Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

scientific article published in Nature

Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus

scientific article published on 18 August 2016

Attenuation of Replication-Competent Adenovirus Serotype 26 Vaccines by Vectorization

scientific article

Augmented replicative capacity of the boosting antigen improves the protective efficacy of heterologous prime-boost vaccine regimens

scientific article

Comparison of shortened mosaic HIV-1 vaccine schedules: a randomised, double-blind, placebo-controlled phase 1 trial (IPCAVD010/HPX1002) and a preclinical study in rhesus monkeys (NHP 17-22)

scientific article published on 17 February 2020

Construction and evaluation of novel rhesus monkey adenovirus vaccine vectors

scientific article

Differential Outcomes Following Optimization of Simian-Human Immunodeficiency Viruses From Clades AE, B and C

scientific article published on 04 March 2020

Durability and correlates of vaccine protection against Zika virus in rhesus monkeys.

scientific article published in December 2017

Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19)

scientific article published in The Lancet

Fetal Neuropathology in Zika Virus-Infected Pregnant Female Rhesus Monkeys

scientific article published on 28 March 2018

First-in-Human Randomized Controlled Trial of Mosaic HIV-1 Immunogens Delivered via a Modified Vaccinia Ankara Vector

scientific article published on 13 April 2018

Hepatitis C genotype 1 mosaic vaccines are immunogenic in mice and induce stronger T-cell responses than natural strains

scientific article published on 5 December 2012

Hexon hypervariable region-modified adenovirus type 5 (Ad5) vectors display reduced hepatotoxicity but induce T lymphocyte phenotypes similar to Ad5 vectors

scientific article

Immediate Dysfunction of Vaccine-Elicited CD8+ T Cells Primed in the Absence of CD4+ T Cells.

scientific article published on 22 July 2016

Lack of therapeutic efficacy of an antibody to α4β7 in SIVmac251-infected rhesus macaques

scientific article published on 05 September 2019

Longitudinal requirement for CD4+ T cell help for adenovirus vector-elicited CD8+ T cell responses

scientific article

Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques.

scientific article published on June 2016

Origin of rebound virus in chronically SIV-infected Rhesus monkeys following treatment discontinuation

scientific article published on 27 October 2020

Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques

scientific article published on 01 October 2020

Protection against a mixed SHIV challenge by a broadly neutralizing antibody cocktail.

scientific article published on September 2017

Protective efficacy of a global HIV-1 mosaic vaccine against heterologous SHIV challenges in rhesus monkeys ⬇️

scientific article published on 24 October 2013

Protective efficacy of adenovirus/protein vaccines against SIV challenges in rhesus monkeys

scientific article

Protective efficacy of multiple vaccine platforms against Zika virus challenge in rhesus monkeys

scientific article

Publisher Correction: Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

scientific article published in Nature

Rapid Cloning of Novel Rhesus Adenoviral Vaccine Vectors

scientific article published on 3 January 2018

Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys

scientific article published on 11 April 2016

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

scientific article

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

scientific article published on 12 May 2022

Safety and immunogenicity of a Zika purified inactivated virus vaccine given via standard, accelerated, or shortened schedules: a single-centre, double-blind, sequential-group, randomised, placebo-controlled, phase 1 trial

scientific article published on 06 May 2020

Safety, pharmacokinetics and antiviral activity of PGT121, a broadly neutralizing monoclonal antibody against HIV-1: a randomized, placebo-controlled, phase 1 clinical trial

scientific article published on 07 October 2021

Similar Epitope Specificities of IgG and IgA Antibodies Elicited by Ad26 Vector Prime, Env Protein Boost Immunizations in Rhesus Monkeys

scientific article published on 17 July 2018

Sustained maternal antibody and cellular immune responses in pregnant women infected with Zika virus and mother to infant transfer of Zika-specific antibodies

scientific article published on 17 June 2020

Therapeutic and protective efficacy of a dengue antibody against Zika infection in rhesus monkeys.

scientific article published on 4 June 2018

Therapeutic efficacy of an Ad26/MVA vaccine with SIV gp140 protein and vesatolimod in ART-suppressed rhesus macaques

scientific article published on 18 May 2022

Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys

scientific article

Transient CD4+ T Cell Depletion Results in Delayed Development of Functional Vaccine-Elicited Antibody Responses

scientific article

Vaccine protection against Zika virus from Brazil

scientific article

Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection

scientific article

Zika Virus Persistence in the Central Nervous System and Lymph Nodes of Rhesus Monkeys

scientific article (publication date: April 2017)

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