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List of works by Darrell R Borger

A Platform for Rapid Detection of Multiple Oncogenic Mutations With Relevance to Targeted Therapy in Non–Small-Cell Lung Cancer ⬇️

scientific article published on December 23, 2010

A phase 1/2 and biomarker study of preoperative short course chemoradiation with proton beam therapy and capecitabine followed by early surgery for resectable pancreatic ductal adenocarcinoma

scientific article published on 24 May 2014

AMP-activated protein kinase is essential for survival in chronic hypoxia

scientific article published on 24 March 2008

Acquired Resistance to Crizotinib in NSCLC with MET Exon 14 Skipping

scientific article published on 22 June 2016

Activation of PI3K Signaling in Merkel Cell Carcinoma ⬇️

scientific article published on January 18, 2012

Activity of IPI-504, a Novel Heat-Shock Protein 90 Inhibitor, in Patients With Molecularly Defined Non–Small-Cell Lung Cancer ⬇️

scientific article published on October 12, 2010

BRAF V600E mutation identifies a subset of low-grade diffusely infiltrating gliomas in adults

scientific article published in April 2013

BRAF V600E mutations are common in pleomorphic xanthoastrocytoma: diagnostic and therapeutic implications

scientific article

Biliary Adenofibroma of Liver: Morphology, Tumor Genetics, and Outcomes in 6 Cases

scientific article published on 6 March 2017

Branched chain in situ hybridization for albumin as a marker of hepatocellular differentiation: evaluation of manual and automated in situ hybridization platforms.

scientific article

Case records of the Massachusetts General Hospital. Case 14-2013. A 70-year-old woman with vaginal bleeding

scientific article published in May 2013

Circulating oncometabolite 2-hydroxyglutarate is a potential surrogate biomarker in patients with isocitrate dehydrogenase-mutant intrahepatic cholangiocarcinoma

scientific article

Clinical Grade "SNaPshot" Genetic Mutation Profiling in Multiple Myeloma

scientific article

Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.

scientific article published on 30 March 2016

Decreased survival in EGFR gene amplified vulvar carcinoma

scientific article published on 3 September 2008

Detection of Dual IDH1 and IDH2 Mutations by Targeted Next-Generation Sequencing in Acute Myeloid Leukemia and Myelodysplastic Syndromes.

scientific article

Detection of novel actionable genetic changes in salivary duct carcinoma helps direct patient treatment

scientific article

Dual HER2 targeting impedes growth of HER2 gene-amplified uterine serous carcinoma xenografts

scientific article

EZH2 codon 641 mutations are common in BCL2-rearranged germinal center B cell lymphomas

scientific article (publication date: 2011)

Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma

scientific article published on February 2016

Epigenetic regulation of CD133 and tumorigenicity of CD133 positive and negative endometrial cancer cells

scientific article

Erratum to: The Ability to Diagnose Intrahepatic Cholangiocarcinoma Definitively Using Novel Branched DNA-Enhanced Albumin RNA In Situ Hybridization Technology

scientific article published on 10 January 2015

Frequent Mutation of Isocitrate Dehydrogenase (IDH)1 and IDH2 in Cholangiocarcinoma Identified Through Broad-Based Tumor Genotyping ⬇️

scientific article published on December 16, 2011

Genomic characterization of human brain metastases identifies drivers of metastatic lung adenocarcinoma

scientific article published on 23 March 2020

Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets

scientific article

HER2 over-expressing high grade endometrial cancer expresses high levels of p95HER2 variant

scientific article

Inactivation of the tumor suppressor WTX in a subset of pediatric tumors

scientific article published on 05 November 2013

Inhibition of Hedgehog signaling antagonizes serous ovarian cancer growth in a primary xenograft model

scientific article (publication date: 2011)

Isocitrate dehydrogenase 1 (IDH1) mutation in breast adenocarcinoma is associated with elevated levels of serum and urine 2-hydroxyglutarate

scientific article

L265P mutation and loss are early mutational events in primary central nervous system diffuse large B-cell lymphomas

scientific article published on 01 February 2019

Microsatellite instability in gallbladder carcinoma

scientific article published on 14 February 2015

Molecular Heterogeneity and Receptor Coamplification Drive Resistance to Targeted Therapy in MET-Amplified Esophagogastric Cancer

scientific article published on 2 October 2015

Mutational analysis and clinical correlation of metastatic colorectal cancer

scientific article

Mutational and clinical predictors of pathologic complete response in the treatment of locally advanced rectal cancer

scientific article

Phase 1/2 study of everolimus in advanced hepatocellular carcinoma

scientific article

Prognosis and Clinicopathologic Features of Patients With Advanced Stage Isocitrate Dehydrogenase (IDH) Mutant and IDH Wild-Type Intrahepatic Cholangiocarcinoma

scientific article

Prospective serial evaluation of 2-hydroxyglutarate, during treatment of newly diagnosed acute myeloid leukemia, to assess disease activity and therapeutic response

scientific article

Prospective, high-throughput molecular profiling of human gliomas ⬇️

scientific article published on July 22, 2012

RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer

scientific article

Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine

scientific article published on May 2010

Ridaforolimus improves the anti-tumor activity of dual HER2 blockade in uterine serous carcinoma in vivo models with HER2 gene amplification and PIK3CA mutation

scientific article

Squamous Cell Carcinoma of the Vulva: A Subclassification of 97 Cases by Clinicopathologic, Immunohistochemical, and Molecular Features (p16, p53, and EGFR).

scientific article published on August 2015

Standardized decision support in next generation sequencing reports of somatic cancer variants

scientific article published on 04 April 2014

Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in liposarcoma

scientific article

Targetable signaling pathway mutations are associated with malignant phenotype in IDH-mutant gliomas.

scientific article

Targeted sequencing of SMO and AKT1 in anterior skull base meningiomas

scientific article published on 25 November 2016

Targeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53

scientific article

The Ability to Diagnose Intrahepatic Cholangiocarcinoma Definitively Using Novel Branched DNA-Enhanced Albumin RNA In Situ Hybridization Technology

scientific article published on 18 December 2014

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