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List of works by Kirkwood F Adams

Acute heart failure associated with high admission blood pressure - A distinct vascular disorder?

Acute heart failure clinical drug development: from planning to proof of activity to phase III.

scientific article published on 28 September 2010

Acute heart failure syndromes: clinical scenarios and pathophysiologic targets for therapy

scientific article published on June 2007

Admission or changes in renal function during hospitalization for worsening heart failure predict postdischarge survival: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-CH

scientific article published on May 2008

Anemia as a risk factor and therapeutic target in heart failure

scientific article published in September 2004

Assessment of Limitations to Optimization of Guideline-Directed Medical Therapy in Heart Failure From the GUIDE-IT Trial: A Secondary Analysis of a Randomized Clinical Trial

scientific article published on 22 April 2020

Association between adrenergic receptor genotypes and beta-blocker dose in heart failure patients: analysis from the HF-ACTION DNA substudy

scientific article published on 31 October 2012

Beta-blocker use and outcomes among hospitalized heart failure patients

scientific article published in June 2006

Biomarker guided therapy for heart failure: focus on natriuretic peptides

scientific article published on July 2010

Biomarker-guided therapies in heart failure: a forum for unified strategies

scientific article published in August 2013

Biomarkers of myocardial stress and fibrosis as predictors of mode of death in patients with chronic heart failure

scientific article

Blood pressure reactivity to psychological stress is associated with clinical outcomes in patients with heart failure

scientific article published on 12 July 2017

Cardiac Myosin Activation with Omecamtiv Mecarbil in Systolic Heart Failure

scientific article published on 13 November 2020

Characteristics and outcomes of patients hospitalized for heart failure in the United States: rationale, design, and preliminary observations from the first 100,000 cases in the Acute Decompensated Heart Failure National Registry (ADHERE).

scientific article

Charting a roadmap for heart failure biomarker studies

scientific article

Chronic Oral Study of Myosin Activation to Increase Contractility in Heart Failure (COSMIC-HF): a phase 2, pharmacokinetic, randomised, placebo-controlled trial

scientific article published on 30 November 2016

Clinical outcomes in patients on beta-blocker therapy admitted with worsening chronic heart failure

scientific article

Clinical trials of pharmacological therapies in acute heart failure syndromes: lessons learned and directions forward

scientific article published on March 2010

Combination of isosorbide dinitrate and hydralazine in blacks with heart failure

scientific article

Coping Effectively With Heart Failure (COPE-HF): Design and Rationale of a Telephone-Based Coping Skills Intervention ⬇️

scientific article published on January 21, 2011

Coping styles in heart failure patients with depressive symptoms

scientific article published on October 2009

Design considerations and proposed template for clinical trials in hospitalized patients with decompensated chronic heart failure

scientific article published on 01 February 2003

Digoxin and reduction in mortality and hospitalization in heart failure: a comprehensive post hoc analysis of the DIG trial

scientific article

Dissociation between hemodynamic changes and symptom improvement in patients with advanced congestive heart failure

scientific article published in June 2002

Dose Response of β-Blockers in Adrenergic Receptor Polymorphism Genotypes

scientific article published on 01 August 2018

Early worsening heart failure in patients admitted with acute heart failure--a new outcome measure associated with long-term prognosis?

scientific article published on 28 July 2009

Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure

scientific article published on 01 November 2018

Effect of Natriuretic Peptide-Guided Therapy on Hospitalization or Cardiovascular Mortality in High-Risk Patients With Heart Failure and Reduced Ejection Fraction: A Randomized Clinical Trial

scientific article

Effect of oral digoxin in high-risk heart failure patients: a pre-specified subgroup analysis of the DIG trial

scientific article

Effect of serelaxin on cardiac, renal, and hepatic biomarkers in the Relaxin in Acute Heart Failure (RELAX-AHF) development program: correlation with outcomes

scientific article

Effects of Coping Skills Training on Quality of Life, Disease Biomarkers, and Clinical Outcomes in Patients With Heart Failure: A Randomized Clinical Trial

scientific article published on January 2017

Effects of Serelaxin in Patients with Acute Heart Failure

scientific article published on 01 August 2019

Efficacy and Safety of Tolvaptan in Patients Hospitalized With Acute Heart Failure

scientific article published on 13 September 2016

Evaluation of the Incremental Prognostic Utility of Increasingly Complex Testing in Chronic Heart Failure

scientific article published in June 2015

Evolution of natriuretic peptide biomarkers in heart failure: Implications for clinical care and clinical trials

scientific article published on 28 January 2018

Heart failure as an endpoint in heart failure and non-heart failure cardiovascular clinical trials: the need for a consensus definition

scientific article published in February 2008

Heart rate: a prognostic factor and therapeutic target in chronic heart failure. The distinct roles of drugs with heart rate-lowering properties

scientific article published on 03 December 2013

Hyponatraemia in acute heart failure is a marker of increased mortality but not when associated with hyperglycaemia

scientific article

Improvement in hyponatremia during hospitalization for worsening heart failure is associated with improved outcomes: insights from the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) trial

article

Improving cardiovascular clinical trials conduct in the United States: recommendation from clinicians, researchers, sponsors, and regulators

scientific article

In-hospital mortality in patients with acute decompensated heart failure requiring intravenous vasoactive medications: an analysis from the Acute Decompensated Heart Failure National Registry (ADHERE).

scientific article published in July 2005

In-hospital worsening heart failure

scientific article published on 03 August 2015

Long-Chain Omega-3 Fatty Acid Supplements in Depressed Heart Failure Patients: Results of the OCEAN Trial

scientific article published on 08 August 2018

Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: results from the Outcomes of a Prospective Trial of Intravenous Milrinone for Exacerbations of Chronic Heart Failure (OPTIME-

scientific article published on 2 May 2005

N-terminal pro-brain natriuretic peptide and exercise capacity in chronic heart failure: data from the Heart Failure and a Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION) study

scientific article published in October 2009

NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF

scientific article published on 02 January 2019

Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction

scientific article published on 01 September 2019

Omecamtiv Mecarbil in Chronic Heart Failure with Reduced Ejection Fraction, GALACTIC-HF: Baseline Characteristics and Comparison with Contemporary Clinical Trials

scientific article published on 27 September 2020

Phase III clinical trial end points in acute heart failure syndromes: A virtual roundtable with the acute heart failure syndromes international working group

article

Prognostic Value of Blood Urea Nitrogen in Patients Hospitalized With Worsening Heart Failure: Insights From the Acute and Chronic Therapeutic Impact of a Vasopressin Antagonist in Chronic Heart Failure (ACTIV in CHF) Study

article

Prospective assessment of the occurrence of anemia in patients with heart failure: results from the Study of Anemia in a Heart Failure Population (STAMINA-HFP) Registry

scientific article published in May 2009

Prospective evaluation of the association between cardiac troponin T and markers of disturbed erythropoiesis in patients with heart failure

scientific article published in December 2010

Prospective evaluation of the association between hemoglobin concentration and quality of life in patients with heart failure

scientific article published in December 2009

Rapid clinical assessment of patients with acute heart failure: first blood pressure and oxygen saturation--is that all we need?

scientific article published on 17 April 2009

Rationale and design of the GUIDE-IT study: Guiding Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure

scientific article

Reactive hyperemia is associated with adverse clinical outcomes in heart failure

scientific article

Relation between dose of loop diuretics and outcomes in a heart failure population: results of the ESCAPE trial

scientific article

Relationship of depression to death or hospitalization in patients with heart failure

scientific article published in February 2007

Relationship of serum digoxin concentration to mortality and morbidity in women in the digitalis investigation group trial: a retrospective analysis

scientific article published on 01 August 2005

Risk stratification after hospitalization for decompensated heart failure

scientific article published in December 2004

Risk stratification for in-hospital mortality in acutely decompensated heart failure: classification and regression tree analysis

scientific article

Serelaxin, recombinant human relaxin-2, for treatment of acute heart failure (RELAX-AHF): a randomised, placebo-controlled trial

scientific article

Short-term intravenous milrinone for acute exacerbation of chronic heart failure: a randomized controlled trial

scientific article published in March 2002

Site selection in global clinical trials in patients hospitalized for heart failure: perceived problems and potential solutions

scientific article

Soluble ST2 in ambulatory patients with heart failure: Association with functional capacity and long-term outcomes

scientific article

Surrogate end points in heart failure trials

scientific article published in February 2003

Tezosentan in patients with acute heart failure and acute coronary syndromes: results of the Randomized Intravenous TeZosentan Study (RITZ-4).

scientific article published in May 2003

The Pilot Randomized Study of Nesiritide Versus Dobutamine in Heart Failure (PRESERVD-HF).

scientific article published in September 2005

The effects of exercise on cardiovascular biomarkers in patients with chronic heart failure

scientific article

The pathophysiology of acute heart failure--is it all about fluid accumulation?

scientific article published on January 2008

The problem of decompensated heart failure: nomenclature, classification, and risk stratification

scientific article

Tolvaptan in Patients Hospitalized With Acute Heart Failure: Rationale and Design of the TACTICS and the SECRET of CHF Trials

scientific article

Usefulness of anemia as a predictor of death and rehospitalization in patients with decompensated heart failure

scientific article published in September 2003

Utility of Growth Differentiation Factor-15, A Marker of Oxidative Stress and Inflammation, in Chronic Heart Failure: Insights From the HF-ACTION Study

scientific article published in October 2017

Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure.

scientific article published on 29 December 2009

Worsening depressive symptoms are associated with adverse clinical outcomes in patients with heart failure

scientific article published on January 2011

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